Gene detail

Detailed information of OS493_008377-T1 in Lophelia pertusa

Genomic Location: scaffold_19:3073646...3092221
NR annotation: KAJ7393079.1, hypothetical protein OS493_008377 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6XPS3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 OS=Homo sapiens OX=9606 GN=TPTE2 PE=1 SV=2
Q4R6N0	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 OS=Macaca fascicularis OX=9541 GN=TPTE2 PE=2 SV=1
P56180	Putative tyrosine-protein phosphatase TPTE OS=Homo sapiens OX=9606 GN=TPTE PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001557 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF10409 all species →	PTEN_C2	C2 domain of PTEN tumour-suppressor protein	Domain	Interproscan
PF00102 all species →	Y_phosphatase	Protein-tyrosine phosphatase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR029023 all species →	Domain	Tensin-type phosphatase domain	Interproscan
IPR035892 all species →	Homologous_superfamily	C2 domain superfamily	Interproscan
IPR014020 all species →	Domain	Tensin phosphatase, C2 domain	Interproscan
IPR045102 all species →	Domain	TPTE, protein tyrosine phosphatase-like catalytic domain	Interproscan
IPR027359 all species →	Homologous_superfamily	Voltage-dependent channel domain superfamily	Interproscan
IPR029021 all species →	Homologous_superfamily	Protein-tyrosine phosphatase-like	Interproscan
IPR016130 all species →	Active_site	Protein-tyrosine phosphatase, active site	Interproscan
IPR000387 all species →	Domain	Tyrosine-specific protein phosphatases domain	Interproscan
IPR051281 all species →	Family	Dual-specificity lipid and protein phosphatase	Interproscan
IPR000242 all species →	Domain	Tyrosine-specific protein phosphatase, PTPase domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12305 all species →	PHOSPHATASE WITH HOMOLOGY TO TENSIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016311 all species →	Biological Process	dephosphorylation	Interproscan
GO:0004725 all species →	Molecular Function	protein tyrosine phosphatase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006470 all species →	Biological Process	protein dephosphorylation	Interproscan
GO:0008285 all species →	Biological Process	negative regulation of cell population proliferation	Interproscan
GO:0014065 all species →	Biological Process	obsolete phosphatidylinositol 3-kinase signaling	Interproscan
GO:0016314 all species →	Molecular Function	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	Interproscan
GO:0042995 all species →	Cellular Component	cell projection	Interproscan
GO:0046856 all species →	Biological Process	phosphatidylinositol dephosphorylation	Interproscan
GO:0048870 all species →	Biological Process	cell motility	Interproscan
GO:0051896 all species →	Biological Process	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K18079	TPTE, TPIP; PTEN homologous phosphatase	-	Protein phosphatases and associated proteins	ko01009	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_008377-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

30.2Max TPM

11.7Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	10.52	15.21
polyp at pH7 6	18	18	11.51	17.44
coral polyp · control treatment	16	16	15.09	30.16
coral polyp · oil and dispersant treatment	16	16	11.36	18.68
coral polyp · oil treatment	16	16	13.70	21.14
coral polyp · dispersant treatment	16	16	12.34	21.13
Polyp	10	10	5.53	9.92

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.21
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.18
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	14.12
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.49
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.46
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.70
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.66
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.50
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.93
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.06
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.35
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.75
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.85
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.85
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.83
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.73
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.47
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.17
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	17.44
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.66
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.55
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	14.89
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	14.55
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	14.10
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.54
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.28
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	12.57
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.64
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.52
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.30
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.89
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.41
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.37
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.86
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.85
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.78
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	30.16
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	27.41
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	21.84
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	18.10
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.23
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.16
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	16.25
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	15.05
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.52
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.54
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.05
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.28
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	8.94
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.76
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.51
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.62
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	18.68
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	15.59
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.70
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.62
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.80
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.48
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.29
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.05
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	12.00
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.60
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.21
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.39
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.26
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.10
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.73
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.31
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.14
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	19.99
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	19.74
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	19.62
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.86
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.29
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.73
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.51
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	13.67
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.62
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.23
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.01
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.79
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.05
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.83
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.11
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	21.13
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	20.21
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	16.54
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.25
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.22
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.14
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	14.94
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.67
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.75
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.66
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.42
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	9.94
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	9.69
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.49
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.50
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.97
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	9.92
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	8.12
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	6.16
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	5.96
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	5.76
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	5.35
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	5.12
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	4.84
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	3.21
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	0.89

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.