Detailed information of OS493_009855-T1 in Lophelia pertusa

Genomic Location: scaffold_23:3376025...3401605
NR annotation: KAJ7363692.1, Mitogen-activated protein kinase kinase kinase 4 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP3K4 PE=1 SV=2
O08648Mitogen-activated protein kinase kinase kinase 4 OS=Mus musculus OX=10090 GN=Map3k4 PE=1 SV=2
O14299MAP kinase kinase kinase wis4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=wis4 PE=3 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004248 (this species only)

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF19431
all species →
MEKK4_NMEKK4 N-terminalFamilyInterproscan
PF00069
all species →
PkinaseProtein kinase domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR008271
all species →
Active_siteSerine/threonine-protein kinase, active siteInterproscan
IPR011009
all species →
Homologous_superfamilyProtein kinase-like domain superfamilyInterproscan
IPR000719
all species →
DomainProtein kinase domainInterproscan
IPR050538
all species →
FamilyMitogen-activated protein kinase kinase kinaseInterproscan
IPR045801
all species →
DomainMitogen-activated protein kinase kinase kinase, N-terminalInterproscan
IPR017441
all species →
Binding_siteProtein kinase, ATP binding siteInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR48016
all species →
MAP KINASE KINASE KINASE SSK2-RELATED-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004672
all species →
Molecular Functionprotein kinase activityInterproscan
GO:0006468
all species →
Biological Processprotein phosphorylationInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0000165
all species →
Biological ProcessMAPK cascadeInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K04428MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4EC:2.7.11.25
Protein kinasesko01001deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_009855-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples
110TPM > 0
7Conditions
21.9Max TPM
11.3Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
polyp at pH7 9 18 18 14.66 21.88
polyp at pH7 6 18 18 14.27 20.23
coral polyp · control treatment 16 16 12.60 19.76
coral polyp · oil and dispersant treatment 16 16 8.79 15.79
coral polyp · oil treatment 16 16 12.00 19.36
coral polyp · dispersant treatment 16 16 8.92 14.86
Polyp 10 10 4.69 8.81

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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