Gene detail

Detailed information of OS493_010042-T1 in Lophelia pertusa

Genomic Location: scaffold_24:2173209...2180547
NR annotation: KAJ7337186.1, putative aminopeptidase npepl1 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8NDH3	Probable aminopeptidase NPEPL1 OS=Homo sapiens OX=9606 GN=NPEPL1 PE=1 SV=3
Q5R7G6	Probable aminopeptidase NPEPL1 OS=Pongo abelii OX=9601 GN=NPEPL1 PE=3 SV=2
Q6NSR8	Probable aminopeptidase NPEPL1 OS=Mus musculus OX=10090 GN=Npepl1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007136 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF18295 all species →	Pdase_M17_N2	M17 aminopeptidase N-terminal domain 2	Domain	Interproscan
PF00883 all species →	Peptidase_M17	Cytosol aminopeptidase family, catalytic domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011356 all species →	Family	Peptidase M17, leucine aminopeptidase/peptidase B	Interproscan
IPR041417 all species →	Domain	Probable aminopeptidase NPEPL1, N-terminal	Interproscan
IPR000819 all species →	Domain	Peptidase M17, leucyl aminopeptidase, C-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11963 all species →	LEUCINE AMINOPEPTIDASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0019538 all species →	Biological Process	protein metabolic process	Interproscan
GO:0030145 all species →	Molecular Function	manganese ion binding	Interproscan
GO:0070006 all species →	Molecular Function	metalloaminopeptidase activity	Interproscan
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0008233 all species →	Molecular Function	peptidase activity	Interproscan
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K09611	NPEPL1; probable aminopeptidase NPEPL1	EC:3.4.11.-	Peptidases and inhibitors	ko01002	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_010042-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

80.3Max TPM

42.2Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	52.46	80.29
polyp at pH7 6	18	18	51.35	79.89
coral polyp · control treatment	16	16	44.84	62.96
coral polyp · oil and dispersant treatment	16	16	38.52	53.07
coral polyp · oil treatment	16	16	42.14	60.18
coral polyp · dispersant treatment	16	16	23.28	43.76
Polyp	10	10	38.75	52.31

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	80.29
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	79.02
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	78.44
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	77.21
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	77.13
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	76.45
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	49.68
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	48.16
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	46.58
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	45.06
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	43.97
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	40.07
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	36.33
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	36.33
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	35.32
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	33.40
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	30.56
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	30.29
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	79.89
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	79.88
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	77.89
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	72.46
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	52.08
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	51.69
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	51.48
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	49.51
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	48.02
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	47.98
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	45.77
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	45.25
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	42.29
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	41.99
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	37.39
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	36.66
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	33.28
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	30.82
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	62.96
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	60.20
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	56.28
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	54.90
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	52.73
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	50.44
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	49.52
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	46.35
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	43.16
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	42.99
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	42.90
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	39.97
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	36.26
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	27.83
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	25.84
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	25.14
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	53.07
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	50.37
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	48.61
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	45.88
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	45.35
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	45.13
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	45.06
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	41.76
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	38.09
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	35.71
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	34.88
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	32.54
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	28.67
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	25.14
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	24.53
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	21.46
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	60.18
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	51.27
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	50.01
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	49.85
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	48.73
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	47.65
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	47.50
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	46.57
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	44.76
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	43.53
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	41.49
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	40.39
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	30.83
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	26.36
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	26.17
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.96
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	43.76
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	41.40
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	30.73
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	24.89
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	24.73
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	24.19
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	20.70
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	20.41
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	20.32
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	20.24
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	19.54
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	18.64
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	16.75
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	16.70
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.20
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	14.23
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	52.31
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	42.79
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	42.06
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	41.63
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	38.85
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	37.57
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	37.26
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	35.53
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	30.74
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	28.76

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.