Gene detail

Detailed information of OS493_012706-T1 in Lophelia pertusa

Genomic Location: scaffold_33:2178555...2183961
NR annotation: KAJ7379944.1, hypothetical protein OS493_012706 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8HXY4	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Macaca fascicularis OX=9541 GN=BCKDHA PE=2 SV=1
P12694	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHA PE=1 SV=2
P11178	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Bos taurus OX=9913 GN=BCKDHA PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003055 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00676 all species →	E1_dh	Dehydrogenase E1 component	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001017 all species →	Domain	Dehydrogenase, E1 component	Interproscan
IPR029061 all species →	Homologous_superfamily	Thiamin diphosphate-binding fold	Interproscan
IPR050771 all species →	Family	Alpha-ketoacid dehydrogenase complex E1 component	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43380 all species →	2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016624 all species →	Molecular Function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	Interproscan
GO:0005947 all species →	Cellular Component	obsolete mitochondrial alpha-ketoglutarate dehydrogenase complex	Interproscan
GO:0009083 all species →	Biological Process	branched-chain amino acid catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00166	BCKDHA, bkdA1; 2-oxoisovalerate dehydrogenase E1 component subunit alpha	EC:1.2.4.4	Lipoic acid metabolism	ko00785	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_012706-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

26.2Max TPM

9.5Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	7.25	13.03
polyp at pH7 6	18	18	7.14	12.09
coral polyp · control treatment	16	16	15.12	23.46
coral polyp · oil and dispersant treatment	16	16	9.07	14.32
coral polyp · oil treatment	16	16	11.29	20.66
coral polyp · dispersant treatment	16	16	9.80	26.18
Polyp	10	10	5.64	14.28

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.03
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.78
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.59
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.19
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.34
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.51
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.91
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.58
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.54
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.46
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.26
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.25
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.24
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.76
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.64
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.42
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.26
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.80
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	12.09
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.22
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.64
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.37
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.16
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.32
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.04
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.04
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.96
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.83
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.10
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.71
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.60
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.51
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.31
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.11
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.92
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.69
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	23.46
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	23.39
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	21.71
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	21.30
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	21.23
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	20.61
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	19.74
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	16.38
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.98
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.36
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.46
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.31
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.57
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.30
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.46
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.70
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.32
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.19
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	12.60
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.51
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.24
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.09
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.91
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.72
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.41
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.36
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.07
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.00
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.40
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.71
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.98
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.66
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	20.66
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	20.66
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	17.10
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.73
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.23
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.87
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.91
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.87
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.66
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.62
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.28
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.32
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.61
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.87
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.66
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.51
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	26.18
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.81
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.69
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.02
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.09
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.86
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.65
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.17
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	9.47
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	9.04
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.15
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.83
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.67
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.37
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.62
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.22
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	14.28
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	11.79
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	6.84
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	5.07
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	4.04
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	3.49
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	3.22
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	2.97
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	2.85
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	1.89

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.