Gene detail

Detailed information of OS493_012761-T1 in Lophelia pertusa

Genomic Location: scaffold_33:2715052...2720920
NR annotation: KAJ7379999.1, GTP cyclohydrolase 1 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P22288	GTP cyclohydrolase 1 OS=Rattus norvegicus OX=10116 GN=Gch1 PE=1 SV=1
P30793	GTP cyclohydrolase 1 OS=Homo sapiens OX=9606 GN=GCH1 PE=1 SV=1
Q05915	GTP cyclohydrolase 1 OS=Mus musculus OX=10090 GN=Gch1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003703 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01227 all species →	GTP_cyclohydroI	GTP cyclohydrolase I	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001474 all species →	Family	GTP cyclohydrolase I	Interproscan
IPR018234 all species →	Conserved_site	GTP cyclohydrolase I, conserved site	Interproscan
IPR043133 all species →	Homologous_superfamily	GTP cyclohydrolase I, C-terminal/NADPH-dependent 7-cyano-7-deazaguanine reductase	Interproscan
IPR020602 all species →	Domain	GTP cyclohydrolase I domain	Interproscan
IPR043134 all species →	Homologous_superfamily	GTP cyclohydrolase I, N-terminal domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11109 all species →	GTP CYCLOHYDROLASE I	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003934 all species →	Molecular Function	GTP cyclohydrolase I activity	Interproscan
GO:0046654 all species →	Biological Process	tetrahydrofolate biosynthetic process	Interproscan
GO:0005525 all species →	Molecular Function	GTP binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006729 all species →	Biological Process	tetrahydrobiopterin biosynthetic process	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01495	GCH1, folE; GTP cyclohydrolase IA	EC:3.5.4.16	Folate biosynthesis	ko00790	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_012761-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

108TPM > 0

7Conditions

21.7Max TPM

8.3Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	6.49	10.64
polyp at pH7 6	18	17	8.37	13.45
coral polyp · control treatment	16	16	9.88	20.09
coral polyp · oil and dispersant treatment	16	15	7.50	14.76
coral polyp · oil treatment	16	16	9.61	21.71
coral polyp · dispersant treatment	16	16	7.14	21.59
Polyp	10	10	9.95	18.30

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.64
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.02
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.64
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.58
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.45
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.37
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.24
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.03
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.59
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.24
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.82
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.65
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.21
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.16
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.07
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.71
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.70
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.64
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.45
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.69
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.37
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.72
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.61
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.02
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.62
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.49
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.70
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.02
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.47
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.24
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.11
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.61
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.38
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.20
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.93
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	20.09
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.92
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.92
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.43
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.43
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.39
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.57
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.01
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	8.65
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.44
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.37
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.32
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.30
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.27
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.57
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.39
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.76
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.84
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.65
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.72
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.48
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.23
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.55
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.40
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.25
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.88
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.75
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.87
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.23
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.91
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.44
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.00
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.71
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.25
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.17
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.12
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.41
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.25
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.53
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.90
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.38
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.37
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.91
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.05
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.00
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.86
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.37
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.53
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	21.59
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.78
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.50
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.09
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.40
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.25
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.73
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.62
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.18
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.78
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.61
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.46
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.01
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.98
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.24
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.06
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	18.30
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	16.88
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	13.79
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	12.25
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	9.53
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	6.68
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	5.93
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	5.72
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	5.43
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	5.03

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.