Gene detail

Detailed information of OS493_014862-T1 in Lophelia pertusa

Genomic Location: scaffold_42:2265913...2272026
NR annotation: KAJ7334538.1, Cell division control protein 7 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O00311	Cell division cycle 7-related protein kinase OS=Homo sapiens OX=9606 GN=CDC7 PE=1 SV=1
Q9Z0H0	Cell division cycle 7-related protein kinase OS=Mus musculus OX=10090 GN=Cdc7 PE=1 SV=2
Q9W3Y1	non-specific serine/threonine protein kinase Cdc7 OS=Drosophila melanogaster OX=7227 GN=Cdc7 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0008255 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR44167 all species →	OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0044773 all species →	Biological Process	mitotic DNA damage checkpoint signaling	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K02214	CDC7; cell division control protein 7	EC:2.7.11.1	DNA replication proteins	ko03032	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_014862-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

85TPM > 0

7Conditions

25.2Max TPM

0.6Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	14	0.39	0.78
polyp at pH7 6	18	10	0.23	0.69
coral polyp · control treatment	16	13	1.92	25.24
coral polyp · oil and dispersant treatment	16	12	0.95	12.54
coral polyp · oil treatment	16	14	0.37	1.46
coral polyp · dispersant treatment	16	15	0.30	0.70
Polyp	10	7	0.16	0.43

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.78
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.76
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.73
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.66
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.61
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.58
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.49
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.45
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.42
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.39
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.38
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.33
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.29
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.15
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.00
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.00
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.00
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.00
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.69
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.55
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.52
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.49
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.49
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.37
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.35
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.35
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.26
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.08
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	25.24
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.07
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.83
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.57
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.54
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.48
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.40
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.39
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.33
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.25
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.24
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.24
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.06
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.00
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.00
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.00
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	12.54
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.60
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.37
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.28
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.23
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.21
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.20
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.18
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.18
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.15
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.13
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.12
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.00
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.00
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.00
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.00
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.46
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.76
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.75
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.61
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.48
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.33
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.29
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.24
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.20
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.19
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.19
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.18
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.17
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.13
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.00
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.00
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.70
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.62
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.45
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.39
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.39
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.37
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.37
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.30
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.28
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.27
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.26
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.20
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.09
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.08
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.06
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.00
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	0.43
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	0.31
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	0.26
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	0.24
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	0.12
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	0.11
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	0.10
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	0.00
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	0.00
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.