Gene detail

Detailed information of OS493_016314-T1 in Lophelia pertusa

Genomic Location: scaffold_50:169279...183415
NR annotation: KAJ7385245.1, Phosphatidylinositol 3-kinase catalytic subunit type 3 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6AZN6	Phosphatidylinositol 3-kinase catalytic subunit type 3 OS=Xenopus laevis OX=8355 GN=pik3c3 PE=2 SV=1
Q6PF93	Phosphatidylinositol 3-kinase catalytic subunit type 3 OS=Mus musculus OX=10090 GN=Pik3c3 PE=1 SV=1
Q8NEB9	Phosphatidylinositol 3-kinase catalytic subunit type 3 OS=Homo sapiens OX=9606 GN=PIK3C3 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003109 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00613 all species →	PI3Ka	Phosphoinositide 3-kinase family, accessory domain (PIK domain)	Repeat	Interproscan
PF00454 all species →	PI3_PI4_kinase	Phosphatidylinositol 3- and 4-kinase	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036940 all species →	Homologous_superfamily	Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR001263 all species →	Domain	Phosphoinositide 3-kinase, accessory (PIK) domain	Interproscan
IPR000403 all species →	Domain	Phosphatidylinositol 3-/4-kinase, catalytic domain	Interproscan
IPR018936 all species →	Conserved_site	Phosphatidylinositol 3/4-kinase, conserved site	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR015433 all species →	Family	Phosphatidylinositol kinase	Interproscan
IPR042236 all species →	Homologous_superfamily	Phosphoinositide 3-kinase, accessory (PIK) domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10048 all species →	PHOSPHATIDYLINOSITOL KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016301 all species →	Molecular Function	kinase activity	Interproscan
GO:0000045 all species →	Biological Process	autophagosome assembly	Interproscan
GO:0000407 all species →	Cellular Component	phagophore assembly site	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005768 all species →	Cellular Component	endosome	Interproscan
GO:0005777 all species →	Cellular Component	peroxisome	Interproscan
GO:0006897 all species →	Biological Process	endocytosis	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0016303 all species →	Molecular Function	1-phosphatidylinositol-3-kinase activity	Interproscan
GO:0030242 all species →	Biological Process	autophagy of peroxisome	Interproscan
GO:0034271 all species →	Cellular Component	phosphatidylinositol 3-kinase complex, class III, type I	Interproscan
GO:0034272 all species →	Cellular Component	phosphatidylinositol 3-kinase complex, class III, type II	Interproscan
GO:0036092 all species →	Biological Process	phosphatidylinositol-3-phosphate biosynthetic process	Interproscan
GO:0046854 all species →	Biological Process	phosphatidylinositol phosphate biosynthetic process	Interproscan
GO:0048015 all species →	Biological Process	phosphatidylinositol-mediated signaling	Interproscan
GO:0052742 all species →	Molecular Function	phosphatidylinositol kinase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for OS493_016314-T1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_016314-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

40.8Max TPM

18.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	21.27	30.95
polyp at pH7 6	18	18	21.10	34.84
coral polyp · control treatment	16	16	19.50	28.09
coral polyp · oil and dispersant treatment	16	16	15.66	23.87
coral polyp · oil treatment	16	16	18.88	24.37
coral polyp · dispersant treatment	16	16	12.46	21.57
Polyp	10	10	19.46	40.78

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	30.95
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	29.35
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	24.42
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	23.34
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	22.42
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	22.22
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	22.13
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	21.82
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.57
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.30
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.29
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.14
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	19.67
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	19.07
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	18.50
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.21
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.26
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.23
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	34.84
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	34.53
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	26.48
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	26.18
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	24.67
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	22.86
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	21.75
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	21.14
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.54
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.11
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.51
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.20
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	18.77
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.64
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.37
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	14.66
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	12.49
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.94
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	28.09
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	26.00
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	24.51
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	23.14
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	22.42
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	21.92
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	20.90
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	20.27
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	19.18
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.92
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.30
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.04
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	16.92
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	15.43
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.53
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	8.41
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	23.87
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	20.98
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	20.88
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	17.79
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	16.51
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	16.31
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	16.31
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	15.42
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.80
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.71
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.64
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.97
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.02
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.63
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.20
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.53
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	24.37
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	23.45
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	22.72
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	22.57
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.58
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	20.69
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	19.27
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.95
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.81
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.74
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.55
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	16.57
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.82
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.19
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	13.83
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.92
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	21.57
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	18.02
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	17.55
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.52
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.29
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	14.82
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.85
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.67
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.11
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.11
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.17
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.00
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.65
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.19
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.14
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.75
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	40.78
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	37.56
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	33.60
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	24.43
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	19.64
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	10.99
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	8.37
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	7.86
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	7.73
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	3.62

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.