Gene detail

Detailed information of OS493_017793-T1 in Lophelia pertusa

Genomic Location: scaffold_57:1938793...1940337
NR annotation: KAJ7379280.1, 7-dehydrocholesterol reductase [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5E9J5	7-dehydrocholesterol reductase OS=Bos taurus OX=9913 GN=DHCR7 PE=2 SV=1
O88455	7-dehydrocholesterol reductase OS=Mus musculus OX=10090 GN=Dhcr7 PE=1 SV=1
Q7ZXH1	7-dehydrocholesterol reductase OS=Xenopus laevis OX=8355 GN=dhcr7 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001865 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01222 all species →	ERG4_ERG24	Ergosterol biosynthesis ERG4/ERG24 family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001171 all species →	Family	Sterol biosynthesis ERG24/DHCR-like	Interproscan
IPR018083 all species →	Conserved_site	Sterol reductase, conserved site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR21257 all species →	DELTA(14)-STEROL REDUCTASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006695 all species →	Biological Process	cholesterol biosynthetic process	Interproscan
GO:0009918 all species →	Molecular Function	obsolete sterol delta7 reductase activity	Interproscan
GO:0016126 all species →	Biological Process	sterol biosynthetic process	Interproscan
GO:0016132 all species →	Biological Process	brassinosteroid biosynthetic process	Interproscan
GO:0016627 all species →	Molecular Function	oxidoreductase activity, acting on the CH-CH group of donors	Interproscan
GO:0030176 all species →	Cellular Component	obsolete integral component of endoplasmic reticulum membrane	Interproscan
GO:0047598 all species →	Molecular Function	7-dehydrocholesterol reductase activity	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0016628 all species →	Molecular Function	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00213	DHCR7; 7-dehydrocholesterol reductase	EC:1.3.1.21	Steroid biosynthesis	ko00100	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_017793-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

15.7Max TPM

5.9Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	6.37	10.55
polyp at pH7 6	18	18	6.31	10.02
coral polyp · control treatment	16	16	6.32	12.71
coral polyp · oil and dispersant treatment	16	16	4.75	9.39
coral polyp · oil treatment	16	16	4.97	9.68
coral polyp · dispersant treatment	16	16	6.87	15.74
Polyp	10	10	5.08	15.26

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.55
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.62
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.13
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.89
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.20
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.66
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.62
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.42
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.15
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.80
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.36
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.28
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.89
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.88
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.66
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.34
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.22
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.96
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.02
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.37
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.36
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.98
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.95
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.87
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.44
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.20
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.29
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.85
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.83
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.48
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.87
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.80
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.30
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.86
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.61
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.52
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.71
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.77
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.75
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.79
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.11
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.64
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.54
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.10
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.84
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.66
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.25
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.92
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.66
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.15
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.40
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.82
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.39
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.48
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.26
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.07
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.37
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.93
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.72
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.27
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.86
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.44
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.25
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.13
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.86
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.66
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.54
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.84
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.68
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.49
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.54
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.22
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.12
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.37
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.08
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.93
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.61
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.45
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.41
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.01
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.66
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.15
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.32
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.49
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.74
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	14.07
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.23
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	9.39
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.99
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.38
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.22
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.11
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.79
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.20
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.15
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.77
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.66
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.56
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.44
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.23
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	15.26
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	8.32
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	5.91
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	4.52
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	4.49
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	4.19
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	2.98
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	2.43
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	1.40
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	1.30

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.