Gene detail

Detailed information of OS493_017985-T1 in Lophelia pertusa

Genomic Location: scaffold_58:1463481...1466481
NR annotation: KAJ7372711.1, Endonuclease III-like protein 1 [Desmophyllum pertusum]
Species abbreviation LPERT · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A7M7B9	Endonuclease III-like protein 1 OS=Gallus gallus OX=9031 GN=NTHL1 PE=2 SV=1
Q2KID2	Endonuclease III-like protein 1 OS=Bos taurus OX=9913 GN=NTHL1 PE=2 SV=1
O35980	Endonuclease III-like protein 1 OS=Mus musculus OX=10090 GN=Nthl1 PE=2 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007382 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00633 all species →	HHH	Helix-hairpin-helix motif	Motif	Interproscan
PF00730 all species →	HhH-GPD	HhH-GPD superfamily base excision DNA repair protein	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000445 all species →	Conserved_site	Helix-hairpin-helix motif	Interproscan
IPR023170 all species →	Homologous_superfamily	Helix-hairpin-helix, base-excision DNA repair, C-terminal	Interproscan
IPR030841 all species →	Family	Endonuclease III-like protein 1	Interproscan
IPR004036 all species →	Conserved_site	Endonuclease III-like, conserved site-2	Interproscan
IPR011257 all species →	Homologous_superfamily	DNA glycosylase	Interproscan
IPR003265 all species →	Domain	HhH-GPD domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43286 all species →	ENDONUCLEASE III-LIKE PROTEIN 1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0003906 all species →	Molecular Function	DNA-(apurinic or apyrimidinic site) endonuclease activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006281 all species →	Biological Process	DNA repair	Interproscan
GO:0006285 all species →	Biological Process	base-excision repair, AP site formation	Interproscan
GO:0019104 all species →	Molecular Function	DNA N-glycosylase activity	Interproscan
GO:0000703 all species →	Molecular Function	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity	Interproscan
GO:0006296 all species →	Biological Process	obsolete nucleotide-excision repair, DNA incision, 5'-to lesion	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0006284 all species →	Biological Process	base-excision repair	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10773	NTHL1, nth; endonuclease III	EC:3.2.2.- EC:4.2.99.18	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern

Expression trend for OS493_017985-T1 global co-expression network