Gene detail

Detailed information of OS493_021117-T1 in Lophelia pertusa

Genomic Location: scaffold_80:288033...297146
NR annotation: KAJ7384488.1, Dual specificity mitogen-activated protein kinase kinase 1 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q90891	Dual specificity mitogen-activated protein kinase kinase 2 OS=Gallus gallus OX=9031 GN=MAP2K2 PE=2 SV=1
Q02750	Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP2K1 PE=1 SV=2
Q01986	Dual specificity mitogen-activated protein kinase kinase 1 OS=Rattus norvegicus OX=10116 GN=Map2k1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001663 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR050915 all species →	Family	MAP kinase kinase	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR47448 all species →	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04368	MAP2K1, MEK1; mitogen-activated protein kinase kinase 1	EC:2.7.12.2	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_021117-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

175.5Max TPM

52.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	45.71	63.62
polyp at pH7 6	18	18	46.10	58.57
coral polyp · control treatment	16	16	72.28	150.00
coral polyp · oil and dispersant treatment	16	16	64.30	175.50
coral polyp · oil treatment	16	16	57.37	92.99
coral polyp · dispersant treatment	16	16	42.18	91.02
Polyp	10	10	28.73	42.91

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	63.62
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	59.81
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	58.45
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	57.24
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	53.43
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	50.35
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	49.71
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	48.30
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	46.36
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	46.02
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	43.84
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	42.55
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	41.27
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	40.08
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	32.31
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	31.17
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	29.72
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	28.47
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	58.57
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	58.36
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	56.28
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	55.79
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	52.68
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	52.56
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	51.74
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	50.53
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	46.39
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	45.26
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	44.51
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	44.41
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	44.25
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	41.13
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	40.47
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	37.35
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	25.85
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	23.65
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	150.00
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	98.30
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	94.60
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	90.61
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	90.38
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	89.05
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	83.93
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	80.18
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	64.16
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	61.49
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	61.38
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	54.27
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	45.10
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	40.85
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	37.91
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.27
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	175.50
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	93.18
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	75.32
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	70.32
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	68.42
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	67.78
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	61.40
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	58.10
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	57.79
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	54.37
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	51.73
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	51.61
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	47.60
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	37.75
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	34.46
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	23.49
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	92.99
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	86.41
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	71.31
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	70.31
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	69.54
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	66.16
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	62.14
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	61.13
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	59.13
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	54.73
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	52.86
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	49.23
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	43.14
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	29.93
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	29.10
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	19.79
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	91.02
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	63.34
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	52.07
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	49.62
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	48.57
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	47.16
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	45.58
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	45.02
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	43.68
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	38.97
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	34.05
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	33.56
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	33.22
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	32.97
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.29
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.75
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	42.91
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	37.02
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	34.74
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	33.49
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	31.69
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	26.98
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	21.47
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	20.95
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	19.50
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	18.57

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.