Gene detail

Detailed information of OS493_021561-T1 in Lophelia pertusa

Genomic Location: scaffold_83:770571...778009
NR annotation: KAJ7358782.1, diphthine synthase [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9H2P9	Diphthine methyl ester synthase OS=Homo sapiens OX=9606 GN=DPH5 PE=1 SV=2
Q9CWQ0	Diphthine methyl ester synthase OS=Mus musculus OX=10090 GN=Dph5 PE=1 SV=2
Q5E982	Diphthine methyl ester synthase OS=Bos taurus OX=9913 GN=DPH5 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003840 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00590 all species →	TP_methylase	Tetrapyrrole (Corrin/Porphyrin) Methylases	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR004551 all species →	Family	Diphthine synthase	Interproscan
IPR035996 all species →	Homologous_superfamily	Tetrapyrrole methylase superfamily	Interproscan
IPR014776 all species →	Homologous_superfamily	Tetrapyrrole methylase, subdomain 2	Interproscan
IPR000878 all species →	Domain	Tetrapyrrole methylase	Interproscan
IPR014777 all species →	Homologous_superfamily	Tetrapyrrole methylase, subdomain 1	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10882 all species →	DIPHTHINE SYNTHASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004164 all species →	Molecular Function	diphthine synthase activity	Interproscan
GO:0017183 all species →	Biological Process	protein histidyl modification to diphthamide	Interproscan
GO:0008168 all species →	Molecular Function	methyltransferase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00586	DPH5; diphthine methyl ester synthase	EC:2.1.1.314	Translation factors	ko03012	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_021561-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

36.2Max TPM

19.3Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	18.56	28.75
polyp at pH7 6	18	18	20.90	32.52
coral polyp · control treatment	16	16	22.75	31.69
coral polyp · oil and dispersant treatment	16	16	19.63	29.88
coral polyp · oil treatment	16	16	24.92	36.16
coral polyp · dispersant treatment	16	16	11.04	24.87
Polyp	10	10	15.64	18.45

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	28.75
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	24.38
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	21.45
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	21.40
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.69
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.19
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.18
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.03
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	19.81
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.40
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.04
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.42
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.47
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.36
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.26
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.06
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.99
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.16
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	32.52
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	28.17
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	26.27
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	25.98
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	24.04
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	23.84
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.79
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.71
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.53
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.98
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.95
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.36
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	17.25
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	16.99
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	16.29
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.46
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.29
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	12.85
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	31.69
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	30.57
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	27.65
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	26.93
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	25.98
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	25.77
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	25.27
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	24.46
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	22.91
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	21.86
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	19.23
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.41
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.02
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	16.81
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	16.19
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.31
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	29.88
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	26.07
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	24.52
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	24.48
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	23.98
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	22.79
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	21.86
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	21.43
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	18.99
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	18.82
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	17.05
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	16.03
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.52
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.76
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.23
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.62
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	36.16
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	33.69
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	30.68
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	30.32
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	29.41
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	28.68
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	27.11
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	26.64
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	26.04
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	22.96
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	22.10
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.43
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	20.61
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	17.53
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.80
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.54
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	24.87
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	21.54
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	18.11
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	14.72
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.25
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.03
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.70
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	9.92
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.87
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.81
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.95
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.29
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.18
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.14
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.92
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.32
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	18.45
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	18.12
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	17.79
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	17.71
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	17.11
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	16.34
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	15.90
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	15.88
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	14.71
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	4.35

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.