Gene detail

Detailed information of OS493_022689-T1 in Lophelia pertusa

Genomic Location: scaffold_96:20274...50814
NR annotation: KAJ7330170.1, hypothetical protein OS493_022689 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q2KIH7	Phenylalanine-4-hydroxylase OS=Bos taurus OX=9913 GN=PAH PE=2 SV=1
P16331	Phenylalanine-4-hydroxylase OS=Mus musculus OX=10090 GN=Pah PE=1 SV=4
P04176	Phenylalanine-4-hydroxylase OS=Rattus norvegicus OX=10116 GN=Pah PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002500 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00351 all species →	Biopterin_H	Biopterin-dependent aromatic amino acid hydroxylase	Domain	Interproscan
PF01842 all species →	ACT	ACT domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR019774 all species →	Domain	Aromatic amino acid hydroxylase, C-terminal	Interproscan
IPR036329 all species →	Homologous_superfamily	Aromatic amino acid monoxygenase, C-terminal domain superfamily	Interproscan
IPR001273 all species →	Family	Aromatic amino acid hydroxylase	Interproscan
IPR018301 all species →	Binding_site	Aromatic amino acid hydroxylase, iron/copper binding site	Interproscan
IPR005961 all species →	Family	Phenylalanine-4-hydroxylase, tetrameric form	Interproscan
IPR019773 all species →	Family	Tyrosine 3-monooxygenase-like	Interproscan
IPR045865 all species →	Homologous_superfamily	ACT-like domain	Interproscan
IPR041912 all species →	Domain	Eukaryotic phenylalanine-4-hydroxylase, catalytic domain	Interproscan
IPR002912 all species →	Domain	ACT domain	Interproscan
IPR036951 all species →	Homologous_superfamily	Aromatic amino acid hydroxylase superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11473 all species →	AROMATIC AMINO ACID HYDROXYLASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016714 all species →	Molecular Function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	Interproscan
GO:0004497 all species →	Molecular Function	monooxygenase activity	Interproscan
GO:0005506 all species →	Molecular Function	iron ion binding	Interproscan
GO:0009072 all species →	Biological Process	aromatic amino acid metabolic process	Interproscan
GO:0004505 all species →	Molecular Function	phenylalanine 4-monooxygenase activity	Interproscan
GO:0006559 all species →	Biological Process	L-phenylalanine catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00500	phhA, PAH; phenylalanine-4-hydroxylase	EC:1.14.16.1	Folate biosynthesis	ko00790	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_022689-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

162.1Max TPM

73.6Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	100.68	162.08
polyp at pH7 6	18	18	88.06	140.96
coral polyp · control treatment	16	16	77.68	139.44
coral polyp · oil and dispersant treatment	16	16	52.23	101.31
coral polyp · oil treatment	16	16	75.97	158.91
coral polyp · dispersant treatment	16	16	51.41	108.36
Polyp	10	10	58.08	103.47

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	162.08
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	155.61
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	154.99
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	153.81
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	153.34
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	145.55
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	109.03
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	106.56
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	86.68
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	86.39
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	83.41
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	78.76
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	68.91
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	64.49
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	61.43
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	57.87
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	41.87
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	41.51
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	140.96
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	136.97
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	134.67
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	127.21
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	110.14
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	108.59
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	89.38
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	87.98
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	82.82
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	77.96
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	76.78
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	75.37
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	75.26
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	70.67
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	58.33
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	52.81
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	42.50
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	36.69
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	139.44
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	131.39
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	121.02
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	110.36
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	90.12
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	83.17
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	82.13
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	71.30
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	67.81
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	66.64
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	61.11
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	53.83
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	44.57
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	41.79
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	41.63
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	36.61
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	101.31
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	87.62
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	87.62
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	74.78
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	71.83
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	56.32
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	49.34
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	41.89
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	41.84
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	40.86
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	37.83
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	35.01
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	30.74
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	30.11
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	27.82
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	20.83
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	158.91
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	130.90
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	118.57
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	109.94
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	100.07
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	88.88
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	85.95
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	63.82
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	56.81
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	53.96
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	53.33
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	49.67
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	43.79
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	41.78
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	34.73
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	24.42
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	108.36
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	86.74
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	84.40
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	83.00
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	82.38
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	70.92
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	54.18
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	49.25
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	39.53
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	35.80
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	27.40
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	25.02
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	23.33
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	17.65
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	17.44
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	17.08
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	103.47
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	91.51
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	77.61
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	64.28
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	62.82
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	51.73
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	33.91
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	32.38
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	32.28
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	30.80

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.