Gene detail

Detailed information of OS493_022690-T1 in Lophelia pertusa

Genomic Location: scaffold_96:55023...72668
NR annotation: KAJ7330171.1, hypothetical protein OS493_022690 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q2KIH7	Phenylalanine-4-hydroxylase OS=Bos taurus OX=9913 GN=PAH PE=2 SV=1
P16331	Phenylalanine-4-hydroxylase OS=Mus musculus OX=10090 GN=Pah PE=1 SV=4
P04176	Phenylalanine-4-hydroxylase OS=Rattus norvegicus OX=10116 GN=Pah PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002500 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01842 all species →	ACT	ACT domain	Domain	Interproscan
PF00351 all species →	Biopterin_H	Biopterin-dependent aromatic amino acid hydroxylase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002912 all species →	Domain	ACT domain	Interproscan
IPR019774 all species →	Domain	Aromatic amino acid hydroxylase, C-terminal	Interproscan
IPR001273 all species →	Family	Aromatic amino acid hydroxylase	Interproscan
IPR019773 all species →	Family	Tyrosine 3-monooxygenase-like	Interproscan
IPR045865 all species →	Homologous_superfamily	ACT-like domain	Interproscan
IPR036951 all species →	Homologous_superfamily	Aromatic amino acid hydroxylase superfamily	Interproscan
IPR018301 all species →	Binding_site	Aromatic amino acid hydroxylase, iron/copper binding site	Interproscan
IPR041912 all species →	Domain	Eukaryotic phenylalanine-4-hydroxylase, catalytic domain	Interproscan
IPR005961 all species →	Family	Phenylalanine-4-hydroxylase, tetrameric form	Interproscan
IPR036329 all species →	Homologous_superfamily	Aromatic amino acid monoxygenase, C-terminal domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11473 all species →	AROMATIC AMINO ACID HYDROXYLASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016714 all species →	Molecular Function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	Interproscan
GO:0004497 all species →	Molecular Function	monooxygenase activity	Interproscan
GO:0005506 all species →	Molecular Function	iron ion binding	Interproscan
GO:0009072 all species →	Biological Process	aromatic amino acid metabolic process	Interproscan
GO:0004505 all species →	Molecular Function	phenylalanine 4-monooxygenase activity	Interproscan
GO:0006559 all species →	Biological Process	L-phenylalanine catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00500	phhA, PAH; phenylalanine-4-hydroxylase	EC:1.14.16.1	Folate biosynthesis	ko00790	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_022690-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

324.7Max TPM

157.7Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	173.09	324.73
polyp at pH7 6	18	18	151.39	253.01
coral polyp · control treatment	16	16	177.76	263.45
coral polyp · oil and dispersant treatment	16	16	133.83	179.36
coral polyp · oil treatment	16	16	173.67	322.68
coral polyp · dispersant treatment	16	16	127.96	215.22
Polyp	10	10	169.82	261.81

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	324.73
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	323.35
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	211.30
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	202.55
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	201.13
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	200.62
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	199.78
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	199.67
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	199.07
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	183.71
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	128.84
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	126.26
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	111.50
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	105.73
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	100.91
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	100.74
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	98.14
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	97.53
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	253.01
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	244.69
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	196.09
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	191.44
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	188.08
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	186.65
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	185.13
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	183.10
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	168.55
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	167.86
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	122.59
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	122.49
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	113.15
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	108.29
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	86.67
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	82.34
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	62.96
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	61.91
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	263.45
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	236.16
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	235.20
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	221.76
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	215.82
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	204.38
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	195.26
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	191.28
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	172.14
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	163.76
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	155.08
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	154.23
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	144.44
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	124.81
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	105.62
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	60.71
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	179.36
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	174.46
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	174.42
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	169.25
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	161.42
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	150.80
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	147.33
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	135.73
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	131.58
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	131.52
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	119.00
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	113.55
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	102.37
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	85.63
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	82.45
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	82.43
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	322.68
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	250.03
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	235.01
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	229.20
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	212.42
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	199.19
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	169.12
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	168.49
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	160.01
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	157.65
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	140.80
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	139.25
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	112.16
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	101.10
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	101.10
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	80.50
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	215.22
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	194.16
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	184.18
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	182.74
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	167.05
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	159.89
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	145.46
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	135.93
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	135.34
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	94.15
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	84.70
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	75.73
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	70.62
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	68.56
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	67.71
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	65.97
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	261.81
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	244.22
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	238.44
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	235.69
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	204.48
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	120.43
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	119.36
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	101.85
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	88.29
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	83.63

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.