Gene detail

Detailed information of OS493_023464-T1 in Lophelia pertusa

Genomic Location: scaffold_104:522475...528167
NR annotation: KAJ7384136.1, DNA damage checkpoint control protein [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8BQY8	Checkpoint protein HUS1 OS=Mus musculus OX=10090 GN=Hus1 PE=2 SV=1
O60921	Checkpoint protein HUS1 OS=Homo sapiens OX=9606 GN=HUS1 PE=1 SV=1
Q8K572	Checkpoint protein HUS1B OS=Mus musculus OX=10090 GN=Hus1b PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005604 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF04005 all species →	Hus1	Hus1-like protein	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR007150 all species →	Family	Checkpoint protein Hus1/Mec3	Interproscan
IPR016580 all species →	Family	Cell cycle checkpoint, Hus1	Interproscan
IPR046938 all species →	Homologous_superfamily	DNA clamp superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12900 all species →	MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000077 all species →	Biological Process	DNA damage checkpoint signaling	Interproscan
GO:0030896 all species →	Cellular Component	checkpoint clamp complex	Interproscan
GO:0005730 all species →	Cellular Component	nucleolus	Interproscan
GO:0000723 all species →	Biological Process	telomere maintenance	Interproscan
GO:0000724 all species →	Biological Process	double-strand break repair via homologous recombination	Interproscan
GO:0006289 all species →	Biological Process	nucleotide-excision repair	Interproscan
GO:0031573 all species →	Biological Process	mitotic intra-S DNA damage checkpoint signaling	Interproscan
GO:0033314 all species →	Biological Process	mitotic DNA replication checkpoint signaling	Interproscan
GO:0035861 all species →	Cellular Component	site of double-strand break	Interproscan
GO:0044778 all species →	Biological Process	meiotic DNA integrity checkpoint signaling	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10903	HUS1; HUS1 checkpoint protein	-	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_023464-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

103TPM > 0

7Conditions

27.9Max TPM

2.7Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	2.28	4.28
polyp at pH7 6	18	15	2.28	3.98
coral polyp · control treatment	16	16	4.10	23.53
coral polyp · oil and dispersant treatment	16	16	3.53	27.93
coral polyp · oil treatment	16	16	2.85	5.50
coral polyp · dispersant treatment	16	15	1.70	5.63
Polyp	10	7	1.59	4.04

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.28
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.55
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.07
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.69
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.68
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.40
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.34
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.11
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.10
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.05
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.05
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.03
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.88
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.80
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.78
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.49
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.40
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.30
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.98
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.88
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.49
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.37
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.32
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.21
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.89
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.76
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.72
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.41
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.29
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.99
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.79
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.64
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.30
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	23.53
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.61
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.89
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.94
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.43
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.30
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.14
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.89
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.75
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.99
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.41
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.27
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.23
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.04
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.01
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.13
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	27.93
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.61
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.33
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.76
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.60
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.22
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.06
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.05
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.88
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.85
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.83
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.12
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.90
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.63
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.42
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.25
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.50
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.15
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.14
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.19
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.62
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.24
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.02
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.98
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.84
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.70
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.87
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.52
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.19
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.15
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.94
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.55
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.63
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.55
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.46
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.28
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.03
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.99
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.91
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.74
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.34
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.21
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.02
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.78
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.61
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.55
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.07
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.00
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	4.04
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	3.49
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	2.44
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	2.06
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	1.49
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	1.20
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	1.15
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	0.00
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	0.00
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.