Gene detail

Detailed information of OS493_025391-T1 in Lophelia pertusa

Genomic Location: scaffold_124:874461...888552
NR annotation: KAJ7371490.1, NPC intracellular cholesterol transporter 1 [Desmophyllum pertusum]
Species abbreviation LPERT · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

OS493_025391-T1

ATGGCCTGGGAAAAGGCATTCTTAGAATACATGAAACATTATGTCAACAACAGCGCCAATGCCAATCTTACCATCAGTTACACAGCAGAGCGCGCTATTCAAGATGAACTGGACCGCGAGAGCGACACTGACATCATCACCATTCTTGTGAGCTACATGATCATGTTTCTGTACATCACTGTGGCTCTTGGACAAGTCAAGAGTTGCAGCAGAATTATGATTGACTCCAAAATTACTCTGGGGTTCAGTGGTATCCTTATAGTGTTATTCTCAGTCGTGGCATCGCTTGGTTTTTGGAGCTACATCGGTGAACCAGCAACCCTTATCATCATTGAGGTTGTGCCATTTCTCGTCTTGGCAGTGGGTGTGGACAACATCTTCATCCTAGTACAGGCATACCAGCGTCAGGACCTTTACGCTGATGAGGATGTCCCTCATAAGGTTGGCCGTGTGTTAGGTGAAGTAGCTCCGAGCATGCTTTTAACTTCTCTGTCGGAGTCTGTCGCATTTGCACTGGGTGCCATGTCAACTATGCCAGCAGTGAGGATATTCTCCTTGTATGCCGCAGCAGCAGTTTTCTTCGACTTTCTGCTACAGATTACAGCTTTCGTGGCAATTCTGTCTCTAGATTCCAAACGTCAAGAAAACAACCGCTTGGACGTTCTTTGTTGCATCAAGGAGCCGAAGTACAACAGCACAGGAGATCAATTGACTTGCGTGTATACTTTCATGAAGAACTACTTTGCTGAAGCTCTGCTTTCTGATTATGTTAGGCCTGTAGTGATTGCCCTTTTCACCGCTTTGCTGTTTTCAAGCATTGCTGTCATACCAAAGATTGATGTAGGCCTGGATCAAGAACTTGCTCTACCCAAGGACTCATACTTACTCAACTGGTTCGCAGACATGAAAGACTACCTACATGTTGGTCCTCCTGTATACTTTGTGGTAAATGAGGGTTATGATTATGAACATACCAAAGGACAGAACAAGATATGCGCCTCGGCTGGGTGTGACTCAAATTCATTGGTGCAGCAAATCTACGTTGCTTCACTGAGGCCTGAGCAGACCAAGATAGCCATGTCAGCGTCTTCTTGGTTAGACGACTACTTCAGCTGGCTTGAACCCAGTGGGCAAGACGCATGTTGCCGTATGAAGTACACCAGCAATGAAACATGCTTTCAATCAACAGTCAAGCCACCTAATTCAACAACTCCGGTGCCCAAAGTCATCTGTTACAACACCACCCTGCCTGTCGTCCCTCCTGTCTTCTGTAACGCTACAGTTGATGACCCTATGTGTTTTCCATGTATGAATATCAGCCAGAAGGGGGAGAGACCAACTCCAAAGCAGTTTGATAAATTCCTGCCGTTTTACCTCAAAGACAACCCAGAGACAAAGTGTACTAAAGGTGGCCATGCAGCTTATGGTGGTGCCCTAAAGTTCGGTGACCCTAAAGACAAACATCTTGTTCAAGCCTCCTACTTTATGTCTTACCACTCAATCCTCAAGACATCTCCCGAGTACACAGCAGCTCTGAAGAATGCGCGTGAGATCGCTAAAAATATCTCGGATACAATTGGTGTTGAGGTGTTCCCATACAGTATATTCTATGTTTTCTATGAACAGTACCTCACGGTGGTGAGGGATACATGGGAGAATCTTTTGTATTGTGCTGCCGCCATTTTTGTCGTGACTTTTGTTCTCCTGGGATTCAACTTGAGTATCGCCCTTATAGTGACCTTTACAGTGGCCATCATTATTGTCAACTTGTTGGGCCTCATGTACCTATGGAATATTTCTCTCAACGCAGTGTCGCTGGTCAACCTTGTTATGGCCGTTGGTATATCAGTAGAATTTTGCTCGCACATTGCACGGTCTTTCACTGTGAACAGACAACACTCTAGAGTAGAAAGAGCTAAAGAAGCTCTAGCAAAAATGGGAAGCTCTGTGTTGAGTGGAATCACGCTAACAAAGTTTTCTGGAATCTTAGTACTTTACTTTTCAAAGTCTCAAATATTTCAGGTTTTCTACTTCCGTATGTATGTTGGCATTGTAATATTAGGGGCTCTACATGGGCTGTTATTTCTACCGATCCTTTTAAGTTACGTTGGCCCTGCCCCCAACAAAGCAACTCCCGTAACCTCGCCTGCTGGCTCTTCCAACAATTCCAATTCCGAGCGTACTCCTTTGATAAGCGCGTAA

Transcript

OS493_025391-T1

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O15118	NPC intracellular cholesterol transporter 1 OS=Homo sapiens OX=9606 GN=NPC1 PE=1 SV=2
O35604	NPC intracellular cholesterol transporter 1 OS=Mus musculus OX=10090 GN=Npc1 PE=1 SV=2
P56941	NPC intracellular cholesterol transporter 1 OS=Sus scrofa OX=9823 GN=NPC1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001652 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF12349 all species →	Sterol-sensing	Sterol-sensing domain of SREBP cleavage-activation	Family	Interproscan
PF02460 all species →	Patched	Patched family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000731 all species →	Domain	Sterol-sensing domain	Interproscan
IPR003392 all species →	Family	Protein patched/dispatched	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45727 all species →	NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0015918 all species →	Biological Process	sterol transport	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0032934 all species →	Molecular Function	sterol binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K12385	NPC1; Niemann-Pick C1 protein	-	Transporters	ko02000	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern

Expression trend for OS493_025391-T1 global co-expression network