Gene detail

Detailed information of OS493_025786-T1 in Lophelia pertusa

Genomic Location: scaffold_129:418259...428119
NR annotation: KAJ7377892.1, 5-aminolevulinate synthase, nonspecific, mitochondrial [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P43091	5-aminolevulinate synthase, non-specific, mitochondrial OS=Opsanus tau OX=8068 GN=alas1 PE=2 SV=1
P13195	5-aminolevulinate synthase, non-specific, mitochondrial OS=Rattus norvegicus OX=10116 GN=Alas1 PE=2 SV=2
P43090	5-aminolevulinate synthase, erythroid-specific, mitochondrial OS=Opsanus tau OX=8068 GN=alas2 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004074 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF09029 all species →	Preseq_ALAS	5-aminolevulinate synthase presequence	Domain	Interproscan
PF00155 all species →	Aminotran_1_2	Aminotransferase class I and II	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR015424 all species →	Homologous_superfamily	Pyridoxal phosphate-dependent transferase	Interproscan
IPR010961 all species →	Domain	Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase	Interproscan
IPR001917 all species →	Binding_site	Aminotransferase, class-II, pyridoxal-phosphate binding site	Interproscan
IPR015421 all species →	Homologous_superfamily	Pyridoxal phosphate-dependent transferase, major domain	Interproscan
IPR015118 all species →	Domain	5-aminolevulinate synthase presequence	Interproscan
IPR050087 all species →	Family	8-amino-7-oxononanoate synthase class-II	Interproscan
IPR004839 all species →	Domain	Aminotransferase, class I/classII	Interproscan
IPR015422 all species →	Homologous_superfamily	Pyridoxal phosphate-dependent transferase, small domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13693 all species →	CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003870 all species →	Molecular Function	5-aminolevulinate synthase activity	Interproscan
GO:0030170 all species →	Molecular Function	pyridoxal phosphate binding	Interproscan
GO:0033014 all species →	Biological Process	tetrapyrrole biosynthetic process	Interproscan
GO:0016740 all species →	Molecular Function	transferase activity	Interproscan
GO:0005759 all species →	Cellular Component	mitochondrial matrix	Interproscan
GO:0006778 all species →	Biological Process	porphyrin-containing compound metabolic process	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0006783 all species →	Biological Process	heme biosynthetic process	Interproscan
GO:0009058 all species →	Biological Process	biosynthetic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00643	E2.3.1.37, ALAS; 5-aminolevulinate synthase	EC:2.3.1.37	Amino acid related enzymes	ko01007	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_025786-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

1,992.2Max TPM

378.7Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	109.83	193.07
polyp at pH7 6	18	18	191.73	436.29
coral polyp · control treatment	16	16	375.12	1,348.40
coral polyp · oil and dispersant treatment	16	16	722.83	1,992.17
coral polyp · oil treatment	16	16	329.35	641.18
coral polyp · dispersant treatment	16	16	558.44	1,269.59
Polyp	10	10	445.69	1,655.46

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	193.07
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	188.87
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	136.39
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	133.38
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	133.22
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	129.43
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	105.61
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	103.88
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	100.10
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	98.57
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	97.37
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	94.07
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	92.04
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	83.02
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	82.41
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	80.35
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	63.27
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	61.88
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	436.29
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	428.65
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	293.45
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	292.65
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	290.10
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	285.00
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	174.45
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	170.54
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	132.05
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	131.75
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	127.91
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	127.62
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	103.04
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	102.97
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	92.60
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	90.30
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	89.39
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	82.41
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1,348.40
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	613.07
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	589.01
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	567.84
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	399.48
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	321.94
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	319.03
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	315.61
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	293.97
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	278.33
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	250.49
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	215.81
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	184.21
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	107.62
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	102.91
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	94.24
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1,992.17
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1,389.87
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1,114.04
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	830.20
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	790.12
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	776.12
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	760.42
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	698.29
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	643.29
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	596.89
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	504.51
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	375.19
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	343.12
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	302.17
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	228.81
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	220.08
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	641.18
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	605.83
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	543.36
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	422.58
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	410.64
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	387.33
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	360.88
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	331.18
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	316.19
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	286.98
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	247.64
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	204.73
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	202.82
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	164.12
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	100.55
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	43.57
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1,269.59
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1,194.97
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1,022.95
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	585.01
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	548.04
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	511.73
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	503.74
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	477.24
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	450.82
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	430.60
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	414.03
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	412.14
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	341.67
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	294.64
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	279.20
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	198.67
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	1,655.46
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	944.53
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	771.15
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	385.21
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	241.90
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	146.56
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	113.81
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	77.94
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	73.51
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	46.81

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.