Genomic Location: scaffold_131:1106451...1118441
NR annotation: KAJ7356286.1, E3 ubiquitin-protein ligase sh3rf3 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families
| CDS |
| OS493_026045-T1 |
| Transcript |
| OS493_026045-T1 |
| Protein |
| OS493_026045-T1 |
| UniProt accession | Description |
|---|---|
| Q8TEJ3 | E3 ubiquitin-protein ligase SH3RF3 OS=Homo sapiens OX=9606 GN=SH3RF3 PE=1 SV=2 |
| Q6NRD3 | E3 ubiquitin-protein ligase SH3RF1 OS=Xenopus laevis OX=8355 GN=sh3rf1 PE=1 SV=1 |
| Q28E95 | E3 ubiquitin-protein ligase SH3RF1 OS=Xenopus tropicalis OX=8364 GN=sh3rf1 PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0006413 (this species only) · gene tree & orthology |
| Ubiquitin family | E3|E3 activity RING|RING · all ubiquitin genes in this species |
| Ubiquitin family | UBD|Other|SH3 · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF14604 all species → | SH3_9 | Variant SH3 domain | Domain | Interproscan |
| PF00097 all species → | zf-C3HC4 | Zinc finger, C3HC4 type (RING finger) | Domain | Interproscan |
| PF00018 all species → | SH3_1 | SH3 domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001452 all species → | Domain | SH3 domain | Interproscan |
| IPR017907 all species → | Conserved_site | Zinc finger, RING-type, conserved site | Interproscan |
| IPR036028 all species → | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR001841 all species → | Domain | Zinc finger, RING-type | Interproscan |
| IPR018957 all species → | Domain | Zinc finger, C3HC4 RING-type | Interproscan |
| IPR035816 all species → | Domain | SH3RF1/SH3RF3, fourth SH3 domain | Interproscan |
| IPR050384 all species → | Family | Endophilin/SH3RF | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR028502 all species → | Domain | E3 ubiquitin-protein ligase SH3RF3, RING finger, HC subclass | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR14167 all species → | SH3 DOMAIN-CONTAINING | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0046872 all species → | Molecular Function | metal ion binding | Interproscan |
| GO:0016567 all species → | Biological Process | protein ubiquitination | Interproscan |
| GO:0032436 all species → | Biological Process | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0046330 all species → | Biological Process | positive regulation of JNK cascade | Interproscan |
| GO:0061630 all species → | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K12171 | SH3RF, POSH; E3 ubiquitin-protein ligase SH3RF | EC:2.3.2.27 | Ubiquitin system | ko04121 | deepkoala |
Transcript abundance of OS493_026045-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| polyp at pH7 9 | 18 | 18 | 10.43 | 18.57 | |
| polyp at pH7 6 | 18 | 18 | 11.92 | 16.94 | |
| coral polyp · control treatment | 16 | 16 | 18.74 | 31.01 | |
| coral polyp · oil and dispersant treatment | 16 | 16 | 31.97 | 57.36 | |
| coral polyp · oil treatment | 16 | 16 | 16.35 | 24.79 | |
| coral polyp · dispersant treatment | 16 | 16 | 19.94 | 49.88 | |
| Polyp | 10 | 10 | 6.14 | 8.40 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR11359523 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 18.57 |
| SRR11359519 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 17.97 |
| SRR11359522 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 17.92 |
| SRR11359518 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 15.33 |
| SRR11359520 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 14.33 |
| SRR11359521 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 13.96 |
| SRR11359497 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 10.71 |
| SRR11359498 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 9.95 |
| SRR11359496 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 9.54 |
| SRR11359510 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 9.23 |
| SRR11359511 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 8.26 |
| SRR11359499 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 8.01 |
| SRR11359495 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 7.28 |
| SRR11359508 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 6.80 |
| SRR11359494 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 6.57 |
| SRR11359509 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 5.56 |
| SRR11359507 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 4.73 |
| SRR11359506 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 3.08 |
| SRR11359524 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 16.94 |
| SRR11359527 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 16.90 |
| SRR11359525 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 16.59 |
| SRR11359526 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 16.07 |
| SRR11359515 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 13.50 |
| SRR11359504 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 12.27 |
| SRR11359505 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 11.92 |
| SRR11359514 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 11.82 |
| SRR11359528 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 11.72 |
| SRR11359529 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 11.69 |
| SRR11359517 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 11.50 |
| SRR11359513 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 10.79 |
| SRR11359516 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 10.36 |
| SRR11359512 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 9.56 |
| SRR11359500 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 9.06 |
| SRR11359501 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 8.69 |
| SRR11359502 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 7.74 |
| SRR11359503 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 7.37 |
| SRR16705990 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 31.01 |
| SRR16705972 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 28.00 |
| SRR16705974 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 24.13 |
| SRR16705965 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 23.77 |
| SRR16705960 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 20.48 |
| SRR16705942 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 18.83 |
| SRR16705943 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 18.20 |
| SRR16705957 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 17.99 |
| SRR16705971 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 17.55 |
| SRR16705946 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 16.95 |
| SRR16705989 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 16.29 |
| SRR16705973 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 15.15 |
| SRR16705991 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 13.97 |
| SRR16705975 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 13.69 |
| SRR16705970 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 12.29 |
| SRR16705992 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 11.59 |
| SRR16705996 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 57.36 |
| SRR16705978 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 52.72 |
| SRR16705979 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 43.91 |
| SRR16705945 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 40.21 |
| SRR16705995 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 39.00 |
| SRR16706004 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 36.96 |
| SRR16705993 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 33.18 |
| SRR16705947 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 33.05 |
| SRR16705944 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 32.29 |
| SRR16705982 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 27.38 |
| SRR16705976 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 22.83 |
| SRR16706005 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 22.40 |
| SRR16705977 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 19.67 |
| SRR16705994 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 19.10 |
| SRR16705948 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 18.55 |
| SRR16705997 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 12.94 |
| SRR16705981 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 24.79 |
| SRR16705983 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 24.32 |
| SRR16705999 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 22.22 |
| SRR16705984 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 19.20 |
| SRR16705949 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 18.39 |
| SRR16705952 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 17.95 |
| SRR16705963 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 17.39 |
| SRR16705961 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 16.63 |
| SRR16706000 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 16.28 |
| SRR16705998 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 16.08 |
| SRR16706001 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 15.55 |
| SRR16705980 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 15.50 |
| SRR16705951 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 14.91 |
| SRR16705962 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 8.63 |
| SRR16705950 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 8.34 |
| SRR16705964 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 5.48 |
| SRR16705987 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 49.88 |
| SRR16705968 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 29.65 |
| SRR16706002 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 26.17 |
| SRR16705955 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 24.03 |
| SRR16705969 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 23.41 |
| SRR16705959 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 22.26 |
| SRR16705988 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 21.98 |
| SRR16705966 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 20.84 |
| SRR16705958 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 18.43 |
| SRR16705967 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 17.28 |
| SRR16706003 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 16.99 |
| SRR16705956 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 16.75 |
| SRR16705954 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 14.41 |
| SRR16705986 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 11.50 |
| SRR16705985 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 4.04 |
| SRR16705953 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 1.46 |
| SRR23025713 | Polyp | not recorded | not recorded | not recorded | - | 8.40 |
| SRR23025710 | Polyp | not recorded | not recorded | not recorded | - | 8.33 |
| SRR23025711 | Polyp | not recorded | not recorded | not recorded | - | 7.99 |
| SRR23025708 | Polyp | not recorded | not recorded | not recorded | - | 7.88 |
| SRR23025712 | Polyp | not recorded | not recorded | not recorded | - | 5.66 |
| SRR7746667 | Polyp | not recorded | not recorded | not recorded | - | 5.25 |
| SRR7746666 | Polyp | not recorded | not recorded | not recorded | - | 5.04 |
| SRR23025709 | Polyp | not recorded | not recorded | not recorded | - | 4.73 |
| SRR7746668 | Polyp | not recorded | not recorded | not recorded | - | 4.59 |
| SRR7746669 | Polyp | not recorded | not recorded | not recorded | - | 3.50 |
Source: CnidoSite RNA-seq expression matrices (LPERT_TPM,
StringTie quantification over 110 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.