Genomic Location: scaffold_134:961943...966584
NR annotation: KAJ7383795.1, hypothetical protein OS493_026329 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families
| CDS |
| OS493_026329-T1 |
| Transcript |
| OS493_026329-T1 |
| Protein |
| OS493_026329-T1 |
| UniProt accession | Description |
|---|---|
| Q9HC07 | Putative divalent cation/proton antiporter TMEM165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 |
| P52875 | Putative divalent cation/proton antiporter TMEM165 OS=Mus musculus OX=10090 GN=Tmem165 PE=1 SV=2 |
| Q4V899 | Putative divalent cation/proton antiporter TMEM165 OS=Rattus norvegicus OX=10116 GN=Tmem165 PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0006997 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01169 all species → | UPF0016 | Uncharacterized protein family UPF0016 | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR049555 all species → | Conserved_site | GDT1-like, conserved site | Interproscan |
| IPR001727 all species → | Family | GDT1-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12608 all species → | TRANSMEMBRANE PROTEIN HTP-1 RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005384 all species → | Molecular Function | manganese ion transmembrane transporter activity | Interproscan |
| GO:0005794 all species → | Cellular Component | Golgi apparatus | Interproscan |
| GO:0015085 all species → | Molecular Function | calcium ion transmembrane transporter activity | Interproscan |
| GO:0032468 all species → | Biological Process | Golgi calcium ion homeostasis | Interproscan |
| GO:0032472 all species → | Biological Process | Golgi calcium ion transport | Interproscan |
| GO:0046873 all species → | Molecular Function | metal ion transmembrane transporter activity | Interproscan |
| GO:0070588 all species → | Biological Process | calcium ion transmembrane transport | Interproscan |
| GO:0071421 all species → | Biological Process | manganese ion transmembrane transport | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K23541 | TMEM165, GDT1; Ca2+/H+ antiporter, TMEM165/GDT1 family | - | Transporters | ko02000 | deepkoala |
Transcript abundance of OS493_026329-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| polyp at pH7 9 | 18 | 18 | 6.55 | 10.62 | |
| polyp at pH7 6 | 18 | 17 | 7.69 | 13.94 | |
| coral polyp · control treatment | 16 | 16 | 15.98 | 30.03 | |
| coral polyp · oil and dispersant treatment | 16 | 16 | 18.39 | 33.50 | |
| coral polyp · oil treatment | 16 | 16 | 12.74 | 24.42 | |
| coral polyp · dispersant treatment | 16 | 15 | 11.29 | 22.07 | |
| Polyp | 10 | 10 | 4.77 | 8.24 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR11359522 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 10.62 |
| SRR11359511 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 10.43 |
| SRR11359510 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 9.40 |
| SRR11359523 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 9.17 |
| SRR11359495 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 7.19 |
| SRR11359494 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 7.15 |
| SRR11359496 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 6.79 |
| SRR11359518 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 6.65 |
| SRR11359520 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 6.25 |
| SRR11359509 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 5.89 |
| SRR11359498 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 5.54 |
| SRR11359508 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 5.33 |
| SRR11359499 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 5.19 |
| SRR11359519 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 5.16 |
| SRR11359497 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 5.15 |
| SRR11359506 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 4.84 |
| SRR11359521 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 4.45 |
| SRR11359507 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 2.75 |
| SRR11359528 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 13.94 |
| SRR11359529 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 13.39 |
| SRR11359515 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 11.27 |
| SRR11359504 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 10.68 |
| SRR11359505 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 10.29 |
| SRR11359512 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 9.90 |
| SRR11359514 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 9.35 |
| SRR11359526 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 8.12 |
| SRR11359527 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 8.11 |
| SRR11359513 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 7.44 |
| SRR11359503 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 6.57 |
| SRR11359501 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 6.28 |
| SRR11359502 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 5.63 |
| SRR11359524 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 5.33 |
| SRR11359517 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 4.83 |
| SRR11359525 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 4.02 |
| SRR11359516 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 3.22 |
| SRR11359500 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 0.00 |
| SRR16705973 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 30.03 |
| SRR16705990 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 27.27 |
| SRR16705972 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 23.61 |
| SRR16705965 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 23.19 |
| SRR16705960 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 22.62 |
| SRR16705957 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 19.01 |
| SRR16705975 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 18.01 |
| SRR16705971 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 16.45 |
| SRR16705943 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 15.58 |
| SRR16705974 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 12.98 |
| SRR16705946 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 10.12 |
| SRR16705970 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 8.51 |
| SRR16705989 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 8.38 |
| SRR16705942 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 8.37 |
| SRR16705991 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 6.70 |
| SRR16705992 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 4.83 |
| SRR16705979 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 33.50 |
| SRR16705995 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 29.63 |
| SRR16705944 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 24.41 |
| SRR16705993 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 23.00 |
| SRR16705945 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 22.53 |
| SRR16705997 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 22.23 |
| SRR16705976 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 19.62 |
| SRR16705948 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 18.70 |
| SRR16706005 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 18.60 |
| SRR16705977 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 18.37 |
| SRR16705978 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 16.70 |
| SRR16706004 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 14.74 |
| SRR16705982 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 11.02 |
| SRR16705947 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 8.45 |
| SRR16705996 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 6.98 |
| SRR16705994 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 5.72 |
| SRR16705999 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 24.42 |
| SRR16706001 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 21.89 |
| SRR16705981 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 20.55 |
| SRR16705952 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 18.32 |
| SRR16705984 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 17.20 |
| SRR16705950 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 13.79 |
| SRR16705998 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 13.04 |
| SRR16705961 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 12.11 |
| SRR16705983 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 11.88 |
| SRR16705949 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 10.89 |
| SRR16706000 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 10.71 |
| SRR16705964 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 9.25 |
| SRR16705951 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 8.15 |
| SRR16705980 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 6.23 |
| SRR16705963 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 3.88 |
| SRR16705962 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 1.54 |
| SRR16705969 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 22.07 |
| SRR16705959 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 16.77 |
| SRR16705988 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 14.81 |
| SRR16705956 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 13.84 |
| SRR16705954 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 13.58 |
| SRR16705987 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 13.45 |
| SRR16706002 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 12.54 |
| SRR16706003 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 12.51 |
| SRR16705967 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 11.33 |
| SRR16705968 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 10.32 |
| SRR16705958 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 10.03 |
| SRR16705966 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 9.86 |
| SRR16705955 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 9.05 |
| SRR16705986 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 8.02 |
| SRR16705985 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 2.51 |
| SRR16705953 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 0.00 |
| SRR23025710 | Polyp | not recorded | not recorded | not recorded | - | 8.24 |
| SRR7746669 | Polyp | not recorded | not recorded | not recorded | - | 8.08 |
| SRR23025711 | Polyp | not recorded | not recorded | not recorded | - | 5.87 |
| SRR23025708 | Polyp | not recorded | not recorded | not recorded | - | 5.61 |
| SRR23025713 | Polyp | not recorded | not recorded | not recorded | - | 5.47 |
| SRR23025712 | Polyp | not recorded | not recorded | not recorded | - | 4.59 |
| SRR23025709 | Polyp | not recorded | not recorded | not recorded | - | 4.58 |
| SRR7746666 | Polyp | not recorded | not recorded | not recorded | - | 2.11 |
| SRR7746668 | Polyp | not recorded | not recorded | not recorded | - | 1.98 |
| SRR7746667 | Polyp | not recorded | not recorded | not recorded | - | 1.11 |
Source: CnidoSite RNA-seq expression matrices (LPERT_TPM,
StringTie quantification over 110 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Lophelia pertusa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 26 | OS493_033550-T1 | 0.881011622459644 |
| Negatively correlated | 3 | OS493_019578-T1 | -0.746101540408491 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Lophelia pertusa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |