Gene detail

Detailed information of OS493_026521-T1 in Lophelia pertusa

Genomic Location: scaffold_137:570036...574545
NR annotation: KAJ7356138.1, Histone-lysine N-methyltransferase, H3 lysine-79 specific [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8TEK3	Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3
Q8INR6	Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Drosophila melanogaster OX=7227 GN=gpp PE=1 SV=2
Q6AW06	Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Caenorhabditis elegans OX=6239 GN=dot-1.1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005416 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08123 all species →	DOT1	Histone methylation protein DOT1	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR029063 all species →	Homologous_superfamily	S-adenosyl-L-methionine-dependent methyltransferase superfamily	Interproscan
IPR025789 all species →	Domain	Histone-lysine N-methyltransferase DOT1 domain	Interproscan
IPR030445 all species →	Family	Histone H3-K79 methyltransferase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR21451 all species →	HISTONE H3 METHYLTRANSFERASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0031151 all species →	Molecular Function	histone H3K79 methyltransferase activity	Interproscan
GO:0000077 all species →	Biological Process	DNA damage checkpoint signaling	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006281 all species →	Biological Process	DNA repair	Interproscan
GO:0051726 all species →	Biological Process	regulation of cell cycle	Interproscan
GO:2000677 all species →	Biological Process	regulation of transcription regulatory region DNA binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for OS493_026521-T1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_026521-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

108TPM > 0

7Conditions

186.0Max TPM

34.6Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	17.88	36.11
polyp at pH7 6	18	17	16.29	30.54
coral polyp · control treatment	16	16	40.20	104.96
coral polyp · oil and dispersant treatment	16	16	50.72	101.34
coral polyp · oil treatment	16	16	26.27	51.78
coral polyp · dispersant treatment	16	16	79.19	186.03
Polyp	10	9	4.52	12.20

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	36.11
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	35.95
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	25.22
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	24.39
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	22.41
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	19.60
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	18.95
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	18.04
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.78
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.38
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.32
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.62
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.33
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.49
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.10
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.25
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.73
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.16
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	30.54
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	28.85
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	26.32
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	23.07
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	21.32
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.23
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.08
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.03
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	18.83
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	18.81
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	16.61
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.56
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.36
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.14
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.76
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.22
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.42
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	104.96
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	71.16
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	49.66
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	46.61
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	46.38
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	44.08
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	41.63
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	39.42
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	34.50
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	31.66
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	31.61
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	30.49
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	26.40
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	20.54
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.78
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.27
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	101.34
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	95.77
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	73.59
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	70.99
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	63.65
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	60.16
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	59.75
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	56.89
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	38.33
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	35.81
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	35.62
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	30.90
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	27.98
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	26.65
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	23.57
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.61
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	51.78
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	50.75
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	40.69
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	32.14
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	29.98
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	27.83
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	27.77
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	25.12
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	23.47
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.63
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.18
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.75
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	16.28
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	16.05
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.36
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.55
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	186.03
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	154.42
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	144.75
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	141.88
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	102.15
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	94.49
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	85.20
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	74.08
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	60.14
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	56.54
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	45.26
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	40.17
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	33.30
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	30.25
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.20
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.23
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	12.20
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	8.21
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	7.41
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	4.53
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	3.82
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	2.94
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	2.79
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	1.91
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	1.41
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.