Gene detail

Detailed information of OS493_026637-T1 in Lophelia pertusa

Genomic Location: scaffold_138:823359...828423
NR annotation: KAJ7327758.1, trans-synaptic signaling by soluble gas, modulating synaptic transmission [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q4ZHR9	Guanylate cyclase soluble subunit beta-1 OS=Canis lupus familiaris OX=9615 GN=GUCY1B1 PE=2 SV=1
Q02153	Guanylate cyclase soluble subunit beta-1 OS=Homo sapiens OX=9606 GN=GUCY1B1 PE=1 SV=1
O54865	Guanylate cyclase soluble subunit beta-1 OS=Mus musculus OX=10090 GN=Gucy1b1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001319 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00211 all species →	Guanylate_cyc	Adenylate and Guanylate cyclase catalytic domain	Domain	Interproscan
PF07701 all species →	HNOBA	Heme NO binding associated	Domain	Interproscan
PF07700 all species →	HNOB	Haem-NO-binding	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001054 all species →	Domain	Adenylyl cyclase class-3/4/guanylyl cyclase	Interproscan
IPR011645 all species →	Domain	Haem NO binding associated	Interproscan
IPR029787 all species →	Homologous_superfamily	Nucleotide cyclase	Interproscan
IPR011644 all species →	Domain	Heme NO-binding	Interproscan
IPR042463 all species →	Homologous_superfamily	Haem NO binding associated domain superfamily	Interproscan
IPR018297 all species →	Conserved_site	Adenylyl cyclase class-4/guanylyl cyclase, conserved site	Interproscan
IPR038158 all species →	Homologous_superfamily	H-NOX domain superfamily	Interproscan
IPR024096 all species →	Homologous_superfamily	NO signalling/Golgi transport ligand-binding domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45655 all species →	GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0009190 all species →	Biological Process	cyclic nucleotide biosynthetic process	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0004383 all species →	Molecular Function	guanylate cyclase activity	Interproscan
GO:0006182 all species →	Biological Process	cGMP biosynthetic process	Interproscan
GO:0020037 all species →	Molecular Function	heme binding	Interproscan
GO:0008074 all species →	Cellular Component	guanylate cyclase complex, soluble	Interproscan
GO:0019934 all species →	Biological Process	cGMP-mediated signaling	Interproscan
GO:0070482 all species →	Biological Process	response to oxygen levels	Interproscan
GO:0016849 all species →	Molecular Function	phosphorus-oxygen lyase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K12319	GUCY1B; guanylate cyclase soluble subunit beta	EC:4.6.1.2	Circadian entrainment	ko04713	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_026637-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

31.7Max TPM

11.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	17.01	25.78
polyp at pH7 6	18	18	15.21	20.19
coral polyp · control treatment	16	16	10.52	28.94
coral polyp · oil and dispersant treatment	16	16	6.60	31.70
coral polyp · oil treatment	16	16	10.65	18.80
coral polyp · dispersant treatment	16	16	5.14	11.36
Polyp	10	10	11.71	28.45

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	25.78
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	25.72
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	25.42
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	23.58
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	21.23
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.01
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.64
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.03
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.94
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.48
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.35
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	14.71
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	14.09
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.73
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.73
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.13
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.10
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.60
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.19
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	18.70
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	18.70
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	18.51
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	17.87
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	17.44
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	17.05
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	16.61
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	16.10
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.70
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.18
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	14.44
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.24
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.72
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.54
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.52
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.79
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.49
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	28.94
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.53
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.26
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.62
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.38
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.61
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.68
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.12
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.96
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.83
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.61
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.55
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.57
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.27
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.76
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.57
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	31.70
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.71
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.70
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.96
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.21
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.78
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.54
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.03
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.89
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.54
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.70
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.58
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.55
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.20
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.96
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.57
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.80
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	16.03
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.87
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.52
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.47
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.32
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.45
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.99
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.40
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.24
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.79
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.01
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.53
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.68
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.39
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.86
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.36
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	9.08
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.61
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.17
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.22
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.80
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.21
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.12
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.93
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.12
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.97
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.35
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.22
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.90
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.44
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.71
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	28.45
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	22.83
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	17.98
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	10.71
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	10.30
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	8.89
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	7.20
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	5.92
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	2.65
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	2.13

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.