Gene detail

Detailed information of OS493_026639-T1 in Lophelia pertusa

Genomic Location: scaffold_138:838948...842344
NR annotation: KAJ7327760.1, trans-synaptic signaling by soluble gas, modulating synaptic transmission [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P16068	Guanylate cyclase soluble subunit beta-1 OS=Bos taurus OX=9913 GN=GUCY1B1 PE=1 SV=1
Q02153	Guanylate cyclase soluble subunit beta-1 OS=Homo sapiens OX=9606 GN=GUCY1B1 PE=1 SV=1
Q4ZHR9	Guanylate cyclase soluble subunit beta-1 OS=Canis lupus familiaris OX=9615 GN=GUCY1B1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001319 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF07700 all species →	HNOB	Haem-NO-binding	Domain	Interproscan
PF00211 all species →	Guanylate_cyc	Adenylate and Guanylate cyclase catalytic domain	Domain	Interproscan
PF07701 all species →	HNOBA	Heme NO binding associated	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001054 all species →	Domain	Adenylyl cyclase class-3/4/guanylyl cyclase	Interproscan
IPR042463 all species →	Homologous_superfamily	Haem NO binding associated domain superfamily	Interproscan
IPR029787 all species →	Homologous_superfamily	Nucleotide cyclase	Interproscan
IPR011644 all species →	Domain	Heme NO-binding	Interproscan
IPR038158 all species →	Homologous_superfamily	H-NOX domain superfamily	Interproscan
IPR024096 all species →	Homologous_superfamily	NO signalling/Golgi transport ligand-binding domain superfamily	Interproscan
IPR011645 all species →	Domain	Haem NO binding associated	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45655 all species →	GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0009190 all species →	Biological Process	cyclic nucleotide biosynthetic process	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0004383 all species →	Molecular Function	guanylate cyclase activity	Interproscan
GO:0006182 all species →	Biological Process	cGMP biosynthetic process	Interproscan
GO:0008074 all species →	Cellular Component	guanylate cyclase complex, soluble	Interproscan
GO:0019934 all species →	Biological Process	cGMP-mediated signaling	Interproscan
GO:0070482 all species →	Biological Process	response to oxygen levels	Interproscan
GO:0020037 all species →	Molecular Function	heme binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K12319	GUCY1B; guanylate cyclase soluble subunit beta	EC:4.6.1.2	Circadian entrainment	ko04713	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_026639-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

107TPM > 0

7Conditions

7.5Max TPM

1.9Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	2.89	5.78
polyp at pH7 6	18	17	2.39	5.46
coral polyp · control treatment	16	16	1.30	3.25
coral polyp · oil and dispersant treatment	16	15	1.02	2.20
coral polyp · oil treatment	16	16	1.85	3.71
coral polyp · dispersant treatment	16	15	0.86	1.92
Polyp	10	10	2.94	7.54

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.78
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.28
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.23
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.39
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.22
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.07
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.92
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.79
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.63
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.57
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.32
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.22
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.13
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.06
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.01
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.97
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.74
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.70
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.46
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.64
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.40
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.07
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.04
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.99
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.84
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.84
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.76
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.54
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.16
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.15
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.52
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.35
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.26
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.24
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.73
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.25
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.08
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.84
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.62
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.62
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.37
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.29
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.26
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.04
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.02
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.01
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.92
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.89
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.86
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.56
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.22
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.20
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.96
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.60
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.51
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.29
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.22
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.10
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.96
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.88
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.87
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.84
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.79
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.46
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.40
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.23
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.00
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.71
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.62
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.40
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.34
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.33
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.33
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.21
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.17
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.95
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.52
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.42
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.19
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.12
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.91
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.91
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.47
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.92
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.60
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.56
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.51
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.46
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.03
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.92
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.68
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.58
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.57
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.52
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.50
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.50
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.29
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.14
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.00
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	7.54
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	7.41
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	4.26
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	3.81
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	1.63
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	1.33
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	0.97
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	0.90
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	0.84
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	0.66

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.