Gene detail

Detailed information of OS493_029251-T1 in Lophelia pertusa

Genomic Location: scaffold_176:215148...219312
NR annotation: KAJ7383286.1, Prostaglandin E synthase 2 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9N0A4	Prostaglandin E synthase 2 OS=Macaca fascicularis OX=9541 GN=PTGES2 PE=1 SV=1
Q66LN0	Prostaglandin E synthase 2 OS=Bos taurus OX=9913 GN=PTGES2 PE=1 SV=3
Q9H7Z7	Prostaglandin E synthase 2 OS=Homo sapiens OX=9606 GN=PTGES2 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006610 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13417 all species →	GST_N_3	Glutathione S-transferase, N-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR034335 all species →	Domain	Prostaglandin E synthase 2, C-terminal	Interproscan
IPR004045 all species →	Domain	Glutathione S-transferase, N-terminal	Interproscan
IPR040079 all species →	Family	Glutathione transferase family	Interproscan
IPR034334 all species →	Family	Prostaglandin E synthase 2	Interproscan
IPR011767 all species →	Active_site	Glutaredoxin active site	Interproscan
IPR036249 all species →	Homologous_superfamily	Thioredoxin-like superfamily	Interproscan
IPR036282 all species →	Homologous_superfamily	Glutathione S-transferase, C-terminal domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12782 all species →	MICROSOMAL PROSTAGLANDIN E SYNTHASE-2	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0050220 all species →	Molecular Function	prostaglandin-E synthase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05309	PTGES2; microsomal prostaglandin-E synthase 2	EC:5.3.99.3	Arachidonic acid metabolism	ko00590	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_029251-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

108TPM > 0

7Conditions

9.9Max TPM

3.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	3.23	4.50
polyp at pH7 6	18	17	3.73	6.58
coral polyp · control treatment	16	16	4.49	7.35
coral polyp · oil and dispersant treatment	16	16	3.12	9.88
coral polyp · oil treatment	16	16	3.70	7.34
coral polyp · dispersant treatment	16	16	2.61	6.42
Polyp	10	9	2.63	6.54

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.50
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.23
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.20
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.16
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.11
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.81
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.69
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.69
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.26
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.15
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.09
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.98
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.86
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.66
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.62
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.99
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.67
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.46
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.58
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.05
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.48
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.17
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.86
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.70
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.13
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.05
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.81
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.72
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.32
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.25
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.85
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.85
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.30
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.03
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.98
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.35
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.81
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.10
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.80
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.58
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.42
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.00
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.73
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.64
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.63
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.39
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.36
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.83
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.81
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.93
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.44
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.88
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.61
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.32
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.26
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.18
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.12
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.93
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.51
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.27
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.16
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.12
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.90
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.64
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.40
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.29
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.25
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.34
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.66
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.53
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.18
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.85
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.84
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.81
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.40
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.07
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.04
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.02
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.95
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.29
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.10
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.04
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.15
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.42
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.36
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.69
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.35
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.34
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.12
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.56
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.29
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.94
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.90
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.78
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.49
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.46
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.35
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.34
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.30
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	6.54
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	5.28
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	3.33
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	3.02
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	2.95
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	2.18
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	1.29
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	1.19
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	0.55
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.