Gene detail

Detailed information of OS493_031040-T1 in Lophelia pertusa

Genomic Location: scaffold_208:104110...112251
NR annotation: KAJ7370625.1, Glutamate--cysteine ligase [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P48506	Glutamate--cysteine ligase catalytic subunit OS=Homo sapiens OX=9606 GN=GCLC PE=1 SV=2
P97494	Glutamate--cysteine ligase catalytic subunit OS=Mus musculus OX=10090 GN=Gclc PE=1 SV=4
P19468	Glutamate--cysteine ligase catalytic subunit OS=Rattus norvegicus OX=10116 GN=Gclc PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001812 (this species only)

Pfam domain

No Pfam domain signature was detected for OS493_031040-T1. This gene does have a gene model — the search simply returned no hit.

InterPro

InterPro term	Type	Description	Source
IPR004308 all species →	Family	Glutamate-cysteine ligase catalytic subunit	Interproscan
IPR014746 all species →	Homologous_superfamily	Glutamine synthetase/guanido kinase, catalytic domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11164 all species →	GLUTAMATE CYSTEINE LIGASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004357 all species →	Molecular Function	glutamate-cysteine ligase activity	Interproscan
GO:0006750 all species →	Biological Process	glutathione biosynthetic process	Interproscan
GO:0017109 all species →	Cellular Component	glutamate-cysteine ligase complex	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for OS493_031040-T1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_031040-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

138.9Max TPM

30.9Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	21.76	37.60
polyp at pH7 6	18	18	22.36	35.35
coral polyp · control treatment	16	16	38.15	76.58
coral polyp · oil and dispersant treatment	16	16	46.75	138.89
coral polyp · oil treatment	16	16	30.43	51.60
coral polyp · dispersant treatment	16	16	41.51	111.53
Polyp	10	10	9.69	24.30

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	37.60
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	34.80
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	29.73
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	29.09
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	28.03
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	27.21
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	26.27
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	25.59
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	21.22
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	18.19
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.53
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.40
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.33
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.19
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.57
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.46
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.76
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.62
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	35.35
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	30.04
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	29.62
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	28.80
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	26.42
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	25.67
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	25.46
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	22.73
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	21.54
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	21.18
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	21.11
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.93
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.57
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.97
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.80
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.39
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.32
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.61
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	76.58
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	60.46
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	56.60
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	51.17
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	46.19
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	43.35
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	43.19
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	43.13
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	42.00
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	36.94
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	34.46
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	26.01
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	15.03
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.71
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.64
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.00
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	138.89
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	75.92
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	56.82
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	56.74
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	49.95
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	49.22
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	46.15
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	46.13
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	43.41
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	40.91
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	37.65
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	36.95
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	32.67
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	17.65
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.28
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.65
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	51.60
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	48.60
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	45.75
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	43.32
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	38.55
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	38.15
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	36.49
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	29.80
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	27.13
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	25.92
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	25.30
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	19.49
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	17.75
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	16.42
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.75
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.82
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	111.53
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	63.62
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	58.56
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	46.53
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	46.01
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	43.15
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	39.18
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	36.85
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	36.49
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	36.45
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	36.32
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	33.83
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	33.70
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	32.66
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.79
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.52
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	24.30
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	13.73
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	11.10
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	10.83
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	9.23
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	9.19
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	8.17
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	4.69
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	3.18
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	2.49

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.