Gene detail

Detailed information of OS493_031365-T1 in Lophelia pertusa

Genomic Location: scaffold_215:419261...435506
NR annotation: KAJ7353918.1, DNA replication initiation factor cdc45 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9YHZ6	Cell division control protein 45 homolog OS=Xenopus laevis OX=8355 GN=cdc45 PE=1 SV=2
O75419	Cell division control protein 45 homolog OS=Homo sapiens OX=9606 GN=CDC45 PE=1 SV=1
Q9Z1X9	Cell division control protein 45 homolog OS=Mus musculus OX=10090 GN=Cdc45 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005311 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02724 all species →	CDC45	CDC45-like protein	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR003874 all species →	Family	CDC45 family	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10507 all species →	CDC45-RELATED PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000727 all species →	Biological Process	double-strand break repair via break-induced replication	Interproscan
GO:0003682 all species →	Molecular Function	chromatin binding	Interproscan
GO:0003688 all species →	Molecular Function	DNA replication origin binding	Interproscan
GO:0003697 all species →	Molecular Function	single-stranded DNA binding	Interproscan
GO:0006270 all species →	Biological Process	DNA replication initiation	Interproscan
GO:0031261 all species →	Cellular Component	DNA replication preinitiation complex	Interproscan
GO:1902977 all species →	Biological Process	mitotic DNA replication preinitiation complex assembly	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K06628	CDC45; cell division control protein 45	-	DNA replication proteins	ko03032	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_031365-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

101TPM > 0

7Conditions

87.0Max TPM

3.6Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	3.00	5.85
polyp at pH7 6	18	14	2.22	5.63
coral polyp · control treatment	16	16	6.66	75.90
coral polyp · oil and dispersant treatment	16	16	6.83	87.04
coral polyp · oil treatment	16	16	2.36	6.06
coral polyp · dispersant treatment	16	14	1.92	4.58
Polyp	10	7	2.21	7.36

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.85
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.22
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.15
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.10
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.76
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.50
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.41
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.13
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.82
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.64
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.60
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.58
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.37
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.20
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.11
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.00
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.29
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.26
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.63
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.10
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.08
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.75
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.49
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.26
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.18
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.14
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.41
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.97
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.62
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.41
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.08
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.91
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	75.90
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.42
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.18
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.73
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.25
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.56
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.36
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.03
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.64
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.48
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.26
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.01
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.90
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.78
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.62
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.43
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	87.04
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.27
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.94
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.90
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.85
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.52
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.51
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.19
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.18
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.11
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.01
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.83
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.77
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.44
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.38
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.37
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.06
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.66
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.93
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.48
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.79
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.76
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.24
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.01
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.00
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.59
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.25
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.12
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.06
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.01
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.44
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.44
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.58
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.48
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.98
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.49
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.49
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.21
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.10
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.94
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.79
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.71
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.71
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.12
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.11
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.02
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.00
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.00
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	7.36
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	4.21
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	2.60
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	2.54
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	2.46
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	1.60
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	1.34
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	0.00
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	0.00
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.