Genomic Location: scaffold_219:561852...585892
NR annotation: KAJ7376946.1, Cilia- and flagella-associated protein 43 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families
| CDS |
| OS493_031542-T1 |
| Transcript |
| OS493_031542-T1 |
| Protein |
| OS493_031542-T1 |
| UniProt accession | Description |
|---|---|
| A0A1L8GXY4 | Cilia- and flagella-associated protein 43 OS=Xenopus laevis OX=8355 GN=cfap43 PE=2 SV=1 |
| E9Q7R9 | Cilia- and flagella-associated protein 43 OS=Mus musculus OX=10090 GN=Cfap43 PE=1 SV=1 |
| Q9JID1 | Programmed cell death protein 4 OS=Rattus norvegicus OX=10116 GN=Pdcd4 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003706 (this species only) · gene tree & orthology |
| Ubiquitin family | UBD|Other|Beta-prp · all ubiquitin genes in this species |
| Ubiquitin family | E3|E3 adaptor Cullin RING|DWD · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02847 all species → | MA3 | MA3 domain | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR015943 all species → | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR003891 all species → | Domain | Initiation factor eIF-4 gamma, MA3 | Interproscan |
| IPR001680 all species → | Repeat | WD40 repeat | Interproscan |
| IPR036322 all species → | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR016024 all species → | Homologous_superfamily | Armadillo-type fold | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR14885 all species → | UNCHARACTERIZED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005930 all species → | Cellular Component | axoneme | Interproscan |
| GO:0060271 all species → | Biological Process | cilium assembly | Interproscan |
OS493_031542-T1.Transcript abundance of OS493_031542-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| polyp at pH7 9 | 18 | 18 | 20.76 | 34.57 | |
| polyp at pH7 6 | 18 | 18 | 23.07 | 35.68 | |
| coral polyp · control treatment | 16 | 16 | 35.82 | 77.48 | |
| coral polyp · oil and dispersant treatment | 16 | 16 | 36.38 | 58.68 | |
| coral polyp · oil treatment | 16 | 16 | 33.33 | 49.72 | |
| coral polyp · dispersant treatment | 16 | 16 | 44.91 | 84.75 | |
| Polyp | 10 | 10 | 13.01 | 20.86 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR11359523 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 34.57 |
| SRR11359522 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 33.14 |
| SRR11359518 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 25.98 |
| SRR11359510 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 25.64 |
| SRR11359520 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 25.47 |
| SRR11359519 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 24.82 |
| SRR11359511 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 24.48 |
| SRR11359521 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 23.68 |
| SRR11359494 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 20.34 |
| SRR11359495 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 19.25 |
| SRR11359499 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 17.28 |
| SRR11359509 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 16.96 |
| SRR11359498 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 16.66 |
| SRR11359508 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 16.08 |
| SRR11359497 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 14.21 |
| SRR11359496 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 13.69 |
| SRR11359507 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 12.09 |
| SRR11359506 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 9.27 |
| SRR11359529 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 35.68 |
| SRR11359528 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 34.65 |
| SRR11359515 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 31.08 |
| SRR11359505 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 30.65 |
| SRR11359504 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 28.69 |
| SRR11359527 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 28.64 |
| SRR11359526 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 28.23 |
| SRR11359514 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 27.26 |
| SRR11359502 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 23.09 |
| SRR11359503 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 22.47 |
| SRR11359500 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 20.02 |
| SRR11359501 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 17.84 |
| SRR11359516 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 17.76 |
| SRR11359517 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 16.76 |
| SRR11359513 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 15.42 |
| SRR11359525 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 13.56 |
| SRR11359512 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 12.52 |
| SRR11359524 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 10.93 |
| SRR16705990 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 77.48 |
| SRR16705973 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 74.08 |
| SRR16705960 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 46.43 |
| SRR16705971 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 39.63 |
| SRR16705965 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 35.26 |
| SRR16705957 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 32.85 |
| SRR16705991 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 32.41 |
| SRR16705974 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 31.59 |
| SRR16705942 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 30.71 |
| SRR16705972 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 29.31 |
| SRR16705989 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 27.56 |
| SRR16705975 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 26.16 |
| SRR16705992 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 24.82 |
| SRR16705943 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 24.37 |
| SRR16705946 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 22.31 |
| SRR16705970 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 18.19 |
| SRR16705977 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 58.68 |
| SRR16705997 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 57.33 |
| SRR16705948 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 42.29 |
| SRR16705979 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 41.58 |
| SRR16705978 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 41.55 |
| SRR16705982 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 40.85 |
| SRR16705945 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 40.73 |
| SRR16705993 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 39.54 |
| SRR16705976 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 33.10 |
| SRR16705995 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 32.85 |
| SRR16706004 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 31.98 |
| SRR16706005 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 31.79 |
| SRR16705944 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 29.19 |
| SRR16705996 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 24.73 |
| SRR16705947 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 23.92 |
| SRR16705994 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 12.03 |
| SRR16705951 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 49.72 |
| SRR16705998 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 47.45 |
| SRR16705984 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 45.37 |
| SRR16705983 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 41.21 |
| SRR16705981 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 38.84 |
| SRR16705999 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 38.33 |
| SRR16705952 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 37.97 |
| SRR16706000 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 33.96 |
| SRR16705949 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 33.81 |
| SRR16706001 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 33.64 |
| SRR16705950 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 28.50 |
| SRR16705961 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 26.18 |
| SRR16705963 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 25.22 |
| SRR16705964 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 18.61 |
| SRR16705962 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 18.04 |
| SRR16705980 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 16.35 |
| SRR16705968 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 84.75 |
| SRR16705969 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 67.55 |
| SRR16705955 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 58.59 |
| SRR16705987 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 57.51 |
| SRR16705967 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 52.05 |
| SRR16705988 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 51.59 |
| SRR16706002 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 50.91 |
| SRR16705966 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 49.67 |
| SRR16705954 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 48.34 |
| SRR16705958 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 45.22 |
| SRR16705956 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 36.80 |
| SRR16706003 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 35.81 |
| SRR16705959 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 32.04 |
| SRR16705986 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 30.03 |
| SRR16705985 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 9.38 |
| SRR16705953 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 8.23 |
| SRR23025709 | Polyp | not recorded | not recorded | not recorded | - | 20.86 |
| SRR23025708 | Polyp | not recorded | not recorded | not recorded | - | 18.87 |
| SRR23025711 | Polyp | not recorded | not recorded | not recorded | - | 17.79 |
| SRR23025710 | Polyp | not recorded | not recorded | not recorded | - | 17.70 |
| SRR23025713 | Polyp | not recorded | not recorded | not recorded | - | 15.47 |
| SRR7746669 | Polyp | not recorded | not recorded | not recorded | - | 11.88 |
| SRR7746668 | Polyp | not recorded | not recorded | not recorded | - | 8.61 |
| SRR7746666 | Polyp | not recorded | not recorded | not recorded | - | 8.18 |
| SRR23025712 | Polyp | not recorded | not recorded | not recorded | - | 6.15 |
| SRR7746667 | Polyp | not recorded | not recorded | not recorded | - | 4.54 |
Source: CnidoSite RNA-seq expression matrices (LPERT_TPM,
StringTie quantification over 110 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Lophelia pertusa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 12 | OS493_031544-T1 | 0.916985997665001 |
| Negatively correlated | 5 | OS493_013112-T1 | -0.84077146275587 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Lophelia pertusa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |