Gene detail

Detailed information of OS493_032659-T1 in Lophelia pertusa

Genomic Location: scaffold_246:266798...283161
NR annotation: KAJ7323088.1, tryptophan 2,3-dioxygenase [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q95NN1	Tryptophan 2,3-dioxygenase OS=Tribolium castaneum OX=7070 PE=2 SV=1
O77457	Tryptophan 2,3-dioxygenase OS=Anopheles gambiae OX=7165 GN=AGAP002721 PE=2 SV=1
Q17P71	Tryptophan 2,3-dioxygenase OS=Aedes aegypti OX=7159 GN=AAEL000428 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003312 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03301 all species →	Trp_dioxygenase	Tryptophan 2,3-dioxygenase	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR037217 all species →	Homologous_superfamily	Tryptophan/Indoleamine 2,3-dioxygenase-like	Interproscan
IPR004981 all species →	Family	Tryptophan 2,3-dioxygenase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10138 all species →	TRYPTOPHAN 2,3-DIOXYGENASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0019441 all species →	Biological Process	tryptophan catabolic process to kynurenine	Interproscan
GO:0020037 all species →	Molecular Function	heme binding	Interproscan
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan
GO:0004833 all species →	Molecular Function	tryptophan 2,3-dioxygenase activity	Interproscan
GO:0019442 all species →	Biological Process	tryptophan catabolic process to acetyl-CoA	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00453	TDO2, kynA; tryptophan 2,3-dioxygenase	EC:1.13.11.11	Tryptophan metabolism	ko00380	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_032659-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

73.4Max TPM

28.6Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	17.61	36.05
polyp at pH7 6	18	18	17.78	34.93
coral polyp · control treatment	16	16	38.96	58.46
coral polyp · oil and dispersant treatment	16	16	42.78	73.44
coral polyp · oil treatment	16	16	29.21	56.28
coral polyp · dispersant treatment	16	16	35.66	55.75
Polyp	10	10	16.18	39.35

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	36.05
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	31.45
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	26.39
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	24.39
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	21.68
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.74
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	18.89
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	18.21
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.60
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.46
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.20
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.95
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.74
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.72
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.97
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.61
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.18
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.70
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	34.93
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	34.19
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	25.51
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	23.83
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	22.64
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.29
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	18.19
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	17.17
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.85
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.82
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.49
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	14.53
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.38
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	12.49
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	12.46
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.18
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.72
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.43
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	58.46
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	54.86
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	54.84
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	50.47
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	43.85
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	43.79
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	42.89
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	40.17
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	39.23
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	37.82
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	35.67
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	31.64
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	28.92
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	23.52
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	19.33
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.92
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	73.44
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	65.56
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	59.29
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	59.18
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	49.03
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	48.91
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	48.80
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	48.02
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	34.93
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	32.85
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	31.17
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	29.99
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	28.08
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	27.37
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	24.43
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	23.42
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	56.28
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	47.70
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	46.45
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	40.57
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	36.91
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	34.40
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	33.13
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	29.72
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	26.04
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	22.54
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.98
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.42
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	17.29
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.59
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.43
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.97
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	55.75
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	53.49
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	52.71
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	51.04
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	48.12
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	46.22
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	44.59
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	40.53
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	36.99
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	35.46
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	26.73
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	25.85
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	25.62
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	19.05
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.40
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.04
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	39.35
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	22.30
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	21.35
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	15.81
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	13.51
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	13.06
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	10.83
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	10.34
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	7.80
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	7.43

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.