Genomic Location: scaffold_247:436282...439188
NR annotation: KAJ7389251.1, Protein Wnt-6 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families
| CDS |
| OS493_032719-T1 |
| Transcript |
| OS493_032719-T1 |
| Protein |
| OS493_032719-T1 |
| UniProt accession | Description |
|---|---|
| Q9Y6F9 | Protein Wnt-6 OS=Homo sapiens OX=9606 GN=WNT6 PE=1 SV=2 |
| P22727 | Protein Wnt-6 OS=Mus musculus OX=10090 GN=Wnt6 PE=1 SV=2 |
| Q98SN7 | Protein Wnt-2b OS=Gallus gallus OX=9031 GN=WNT2B PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000203 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00110 all species → | wnt | wnt family | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR005817 all species → | Family | Wnt | Interproscan |
| IPR009143 all species → | Family | Wnt-6 protein | Interproscan |
| IPR043158 all species → | Homologous_superfamily | Wnt, C-terminal domain | Interproscan |
| IPR018161 all species → | Conserved_site | Wnt protein, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12027 all species → | WNT RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005102 all species → | Molecular Function | signaling receptor binding | Interproscan |
| GO:0005576 all species → | Cellular Component | extracellular region | Interproscan |
| GO:0007275 all species → | Biological Process | multicellular organism development | Interproscan |
| GO:0016055 all species → | Biological Process | Wnt signaling pathway | Interproscan |
| GO:0005109 all species → | Molecular Function | frizzled binding | Interproscan |
| GO:0005125 all species → | Molecular Function | cytokine activity | Interproscan |
| GO:0005615 all species → | Cellular Component | extracellular space | Interproscan |
| GO:0030182 all species → | Biological Process | neuron differentiation | Interproscan |
| GO:0045165 all species → | Biological Process | cell fate commitment | Interproscan |
| GO:0060070 all species → | Biological Process | canonical Wnt signaling pathway | Interproscan |
OS493_032719-T1.Transcript abundance of OS493_032719-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| polyp at pH7 9 | 18 | 18 | 7.27 | 10.92 | |
| polyp at pH7 6 | 18 | 18 | 6.20 | 11.79 | |
| coral polyp · control treatment | 16 | 16 | 7.72 | 14.78 | |
| coral polyp · oil and dispersant treatment | 16 | 15 | 2.56 | 5.10 | |
| coral polyp · oil treatment | 16 | 16 | 4.72 | 8.46 | |
| coral polyp · dispersant treatment | 16 | 15 | 3.46 | 7.13 | |
| Polyp | 10 | 10 | 5.43 | 13.37 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR11359519 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 10.92 |
| SRR11359522 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 10.17 |
| SRR11359518 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 9.40 |
| SRR11359523 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 8.85 |
| SRR11359520 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 8.68 |
| SRR11359509 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 8.41 |
| SRR11359508 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 8.33 |
| SRR11359497 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 8.02 |
| SRR11359496 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 7.29 |
| SRR11359521 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 7.09 |
| SRR11359495 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 6.84 |
| SRR11359511 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 6.80 |
| SRR11359498 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 6.76 |
| SRR11359499 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 6.53 |
| SRR11359494 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 6.34 |
| SRR11359510 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 5.51 |
| SRR11359506 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 2.71 |
| SRR11359507 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 2.27 |
| SRR11359515 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 11.79 |
| SRR11359514 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 10.46 |
| SRR11359527 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 8.00 |
| SRR11359526 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 7.80 |
| SRR11359528 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 7.72 |
| SRR11359504 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 6.93 |
| SRR11359505 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 6.65 |
| SRR11359529 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 6.56 |
| SRR11359503 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 6.08 |
| SRR11359502 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 5.89 |
| SRR11359501 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 5.79 |
| SRR11359512 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 5.30 |
| SRR11359516 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 4.60 |
| SRR11359517 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 4.41 |
| SRR11359513 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 3.93 |
| SRR11359525 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 3.59 |
| SRR11359500 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 3.44 |
| SRR11359524 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 2.62 |
| SRR16705974 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 14.78 |
| SRR16705942 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 14.34 |
| SRR16705972 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 12.63 |
| SRR16705960 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 10.78 |
| SRR16705971 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 9.91 |
| SRR16705946 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 8.75 |
| SRR16705943 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 7.51 |
| SRR16705965 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 7.22 |
| SRR16705975 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 7.20 |
| SRR16705991 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 6.60 |
| SRR16705992 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 5.26 |
| SRR16705970 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 4.76 |
| SRR16705973 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 4.48 |
| SRR16705990 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 3.99 |
| SRR16705989 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 3.78 |
| SRR16705957 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 1.46 |
| SRR16705945 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 5.10 |
| SRR16705978 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 3.99 |
| SRR16705982 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 3.57 |
| SRR16705995 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 3.57 |
| SRR16705976 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 3.51 |
| SRR16705996 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 2.97 |
| SRR16706004 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 2.32 |
| SRR16705979 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 2.32 |
| SRR16705944 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 2.17 |
| SRR16705948 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 2.16 |
| SRR16705993 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 2.15 |
| SRR16705947 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 2.05 |
| SRR16705997 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 2.03 |
| SRR16705994 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 1.62 |
| SRR16706005 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 1.37 |
| SRR16705977 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 0.00 |
| SRR16705998 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 8.46 |
| SRR16705983 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 6.74 |
| SRR16705999 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 6.72 |
| SRR16706000 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 5.99 |
| SRR16706001 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 5.86 |
| SRR16705952 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 5.84 |
| SRR16705981 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 5.74 |
| SRR16705980 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 5.17 |
| SRR16705951 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 4.79 |
| SRR16705984 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 3.51 |
| SRR16705949 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 3.42 |
| SRR16705950 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 3.40 |
| SRR16705961 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 3.29 |
| SRR16705964 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 3.01 |
| SRR16705963 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 2.66 |
| SRR16705962 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 0.92 |
| SRR16705959 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 7.13 |
| SRR16705954 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 6.53 |
| SRR16705955 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 6.09 |
| SRR16705956 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 5.76 |
| SRR16705958 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 5.64 |
| SRR16706003 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 4.08 |
| SRR16705988 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 3.59 |
| SRR16706002 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 2.96 |
| SRR16705986 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 2.77 |
| SRR16705967 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 2.62 |
| SRR16705966 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 2.51 |
| SRR16705969 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 1.86 |
| SRR16705985 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 1.84 |
| SRR16705968 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 1.42 |
| SRR16705987 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 0.50 |
| SRR16705953 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 0.00 |
| SRR23025713 | Polyp | not recorded | not recorded | not recorded | - | 13.37 |
| SRR23025711 | Polyp | not recorded | not recorded | not recorded | - | 9.10 |
| SRR23025710 | Polyp | not recorded | not recorded | not recorded | - | 6.90 |
| SRR23025712 | Polyp | not recorded | not recorded | not recorded | - | 6.87 |
| SRR7746666 | Polyp | not recorded | not recorded | not recorded | - | 5.18 |
| SRR23025708 | Polyp | not recorded | not recorded | not recorded | - | 3.81 |
| SRR23025709 | Polyp | not recorded | not recorded | not recorded | - | 3.51 |
| SRR7746669 | Polyp | not recorded | not recorded | not recorded | - | 2.28 |
| SRR7746667 | Polyp | not recorded | not recorded | not recorded | - | 1.66 |
| SRR7746668 | Polyp | not recorded | not recorded | not recorded | - | 1.59 |
Source: CnidoSite RNA-seq expression matrices (LPERT_TPM,
StringTie quantification over 110 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Lophelia pertusa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 24 | OS493_017856-T1 | 0.794340519717371 |
| Negatively correlated | 3 | OS493_021965-T1 | -0.55470868685775 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Lophelia pertusa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |