Gene detail

Detailed information of OS493_033176-T1 in Lophelia pertusa

Genomic Location: scaffold_257:495534...503363
NR annotation: KAJ7352909.1, Leukotriene A-4 hydrolase [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P30349	Leukotriene A-4 hydrolase OS=Rattus norvegicus OX=10116 GN=Lta4h PE=1 SV=3
P09960	Leukotriene A-4 hydrolase OS=Homo sapiens OX=9606 GN=LTA4H PE=1 SV=2
P24527	Leukotriene A-4 hydrolase OS=Mus musculus OX=10090 GN=Lta4h PE=1 SV=4

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004401 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01433 all species →	Peptidase_M1	Peptidase family M1 domain	Domain	Interproscan
PF09127 all species →	Leuk-A4-hydro_C	Leukotriene A4 hydrolase, C-terminal	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR015211 all species →	Domain	Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR038502 all species →	Homologous_superfamily	Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily	Interproscan
IPR014782 all species →	Domain	Peptidase M1, membrane alanine aminopeptidase	Interproscan
IPR034015 all species →	Family	Aminopeptidase, leukotriene A4 hydrolase-like	Interproscan
IPR027268 all species →	Homologous_superfamily	Peptidase M4/M1, CTD superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45726 all species →	LEUKOTRIENE A-4 HYDROLASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0008237 all species →	Molecular Function	metallopeptidase activity	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0004177 all species →	Molecular Function	aminopeptidase activity	Interproscan
GO:0004301 all species →	Molecular Function	epoxide hydrolase activity	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0043171 all species →	Biological Process	peptide catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for OS493_033176-T1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_033176-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

191.1Max TPM

99.6Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	102.13	121.09
polyp at pH7 6	18	18	91.63	120.43
coral polyp · control treatment	16	16	121.55	189.64
coral polyp · oil and dispersant treatment	16	16	91.25	144.51
coral polyp · oil treatment	16	16	123.96	191.14
coral polyp · dispersant treatment	16	16	77.06	114.17
Polyp	10	10	85.07	145.28

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	121.09
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	117.81
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	113.42
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	110.30
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	108.13
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	106.86
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	104.52
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	100.82
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	98.86
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	98.39
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	96.69
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	96.56
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	96.26
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	96.09
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	95.10
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	94.53
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	92.91
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	89.99
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	120.43
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	110.96
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	108.64
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	107.85
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	107.43
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	99.47
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	98.05
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	96.65
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	94.51
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	92.85
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	83.37
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	80.65
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	77.86
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	77.62
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	76.59
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	75.85
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	72.96
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	67.60
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	189.64
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	166.78
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	165.08
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	149.09
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	146.75
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	142.22
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	129.16
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	129.01
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	125.49
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	118.98
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	115.10
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	113.26
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	98.08
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	60.74
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	52.30
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	43.17
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	144.51
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	118.81
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	111.28
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	108.80
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	103.12
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	101.82
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	100.74
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	99.94
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	96.59
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	90.45
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	87.26
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	86.96
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	71.78
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	49.30
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	48.62
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	40.09
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	191.14
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	177.59
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	157.31
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	144.82
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	136.97
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	136.96
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	130.99
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	129.67
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	126.05
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	121.28
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	104.69
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	102.47
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	92.94
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	90.41
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	88.37
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	51.65
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	114.17
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	111.77
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	103.74
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	101.37
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	89.50
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	79.18
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	73.70
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	73.27
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	72.86
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	70.90
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	65.57
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	62.85
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	57.81
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	57.71
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	51.46
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	47.09
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	145.28
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	129.92
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	105.89
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	94.66
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	82.61
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	77.80
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	62.94
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	57.73
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	57.05
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	36.83

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.