Gene detail

Detailed information of OS493_033943-T1 in Lophelia pertusa

Genomic Location: scaffold_278:31107...35763
NR annotation: KAJ7382586.1, Sphingosine kinase 1 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9JIA7	Sphingosine kinase 2 OS=Mus musculus OX=10090 GN=Sphk2 PE=1 SV=2
Q9NRA0	Sphingosine kinase 2 OS=Homo sapiens OX=9606 GN=SPHK2 PE=1 SV=2
Q8CI15	Sphingosine kinase 1 OS=Mus musculus OX=10090 GN=Sphk1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007569 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00781 all species →	DAGK_cat	Diacylglycerol kinase catalytic domain	Family	Interproscan
PF19279 all species →	YegS_C	YegS C-terminal NAD kinase beta sandwich-like domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR016064 all species →	Homologous_superfamily	NAD kinase/diacylglycerol kinase-like domain superfamily	Interproscan
IPR050187 all species →	Family	Lipid Phosphate Formation and Regulation	Interproscan
IPR017438 all species →	Homologous_superfamily	Inorganic polyphosphate/ATP-NAD kinase, N-terminal	Interproscan
IPR001206 all species →	Domain	Diacylglycerol kinase, catalytic domain	Interproscan
IPR045540 all species →	Domain	YegS/DAGK, C-terminal domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12358 all species →	SPHINGOSINE KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0001727 all species →	Molecular Function	lipid kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006665 all species →	Biological Process	sphingolipid metabolic process	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0016310 all species →	Biological Process	phosphorylation	Interproscan
GO:0017050 all species →	Molecular Function	D-erythro-sphingosine kinase activity	Interproscan
GO:0043231 all species →	Cellular Component	intracellular membrane-bounded organelle	Interproscan
GO:0046512 all species →	Biological Process	sphingosine biosynthetic process	Interproscan
GO:0016301 all species →	Molecular Function	kinase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04718	SPHK; sphingosine kinase	EC:2.7.1.91	Tuberculosis	ko05152	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_033943-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

18.1Max TPM

9.5Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	7.25	10.07
polyp at pH7 6	18	18	7.20	10.54
coral polyp · control treatment	16	16	12.99	17.62
coral polyp · oil and dispersant treatment	16	16	13.16	18.13
coral polyp · oil treatment	16	16	10.83	17.13
coral polyp · dispersant treatment	16	16	9.01	16.28
Polyp	10	10	4.65	8.73

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.07
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.83
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.24
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.32
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.22
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.13
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.01
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.88
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.52
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.96
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.75
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.73
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.60
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.24
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.98
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.25
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.61
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.07
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.54
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.72
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.67
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.48
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.31
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.18
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.13
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.44
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.44
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.95
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.85
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.81
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.17
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.88
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.39
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.93
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.88
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.86
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.62
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.00
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	16.39
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	16.25
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	15.61
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	15.52
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	15.45
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.67
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.47
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.05
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.82
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.88
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.73
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.71
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.72
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.92
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	18.13
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	17.53
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	16.54
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	15.93
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	15.62
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	15.27
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.45
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.54
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.00
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	12.24
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.59
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.43
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.26
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.43
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.47
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.11
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	17.13
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.05
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	13.37
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	13.33
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.54
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.60
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.60
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.32
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.13
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.11
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.45
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.41
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.21
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.59
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.86
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.64
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	16.28
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.19
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.79
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.67
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.89
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.55
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.20
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.16
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	9.12
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.69
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.19
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.99
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.54
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.25
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.12
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.57
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	8.73
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	7.14
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	5.69
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	5.18
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	4.07
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	4.06
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	4.06
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	3.53
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	2.34
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	1.76

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.