Gene detail

Detailed information of OS493_033981-T1 in Lophelia pertusa

Genomic Location: scaffold_278:441040...459855
NR annotation: KAJ7382623.1, Indoleamine 2,3-dioxygenase 2 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6ZQW0	Indoleamine 2,3-dioxygenase 2 OS=Homo sapiens OX=9606 GN=IDO2 PE=1 SV=5
F1LV46	Indoleamine 2,3-dioxygenase 2 OS=Rattus norvegicus OX=10116 GN=Ido2 PE=2 SV=4
P14902	Indoleamine 2,3-dioxygenase 1 OS=Homo sapiens OX=9606 GN=IDO1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002752 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01231 all species →	IDO	Indoleamine 2,3-dioxygenase	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR037217 all species →	Homologous_superfamily	Tryptophan/Indoleamine 2,3-dioxygenase-like	Interproscan
IPR000898 all species →	Family	Indoleamine 2,3-dioxygenase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR28657 all species →	INDOLEAMINE 2,3-DIOXYGENASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0019441 all species →	Biological Process	tryptophan catabolic process to kynurenine	Interproscan
GO:0020037 all species →	Molecular Function	heme binding	Interproscan
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan
GO:0004833 all species →	Molecular Function	tryptophan 2,3-dioxygenase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0033754 all species →	Molecular Function	indoleamine 2,3-dioxygenase activity	Interproscan
GO:0034354 all species →	Biological Process	'de novo' NAD biosynthetic process from tryptophan	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00463	IDO, INDO; indoleamine 2,3-dioxygenase	EC:1.13.11.52	African trypanosomiasis	ko05143	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_033981-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

108TPM > 0

7Conditions

29.9Max TPM

7.8Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	7.90	17.22
polyp at pH7 6	18	18	7.66	18.68
coral polyp · control treatment	16	16	8.94	23.51
coral polyp · oil and dispersant treatment	16	16	7.46	18.71
coral polyp · oil treatment	16	16	9.72	21.30
coral polyp · dispersant treatment	16	16	4.28	8.72
Polyp	10	8	8.74	29.89

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.22
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.88
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.56
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.48
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.70
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.27
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.57
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.55
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.92
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.11
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.47
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.98
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.81
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.56
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.00
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.90
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.90
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.36
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	18.68
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	16.57
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.70
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.19
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.38
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.60
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.27
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.14
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.12
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.75
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.58
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.94
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.37
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.64
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.25
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.23
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.04
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.35
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	23.51
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.75
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.90
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.00
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.98
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.65
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.26
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	8.43
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.75
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.94
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.59
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.16
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.04
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.35
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.07
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.66
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	18.71
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.25
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.67
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.72
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.09
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.96
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.62
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.42
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.29
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.93
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.88
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.77
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.11
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.73
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.24
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.97
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.30
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.26
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.16
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.70
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.43
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	13.22
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.48
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.59
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.26
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.25
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.91
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.58
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.53
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.19
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.93
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.68
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.72
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.49
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.06
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.88
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.60
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.44
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.33
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.25
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.19
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.18
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.79
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.32
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.90
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.40
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.23
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.66
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	29.89
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	26.77
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	12.13
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	5.61
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	5.13
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	4.19
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	2.98
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	0.71
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	0.00
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.