Gene detail

Detailed information of OS493_036793-T1 in Lophelia pertusa

Genomic Location: scaffold_384:34431...39969
NR annotation: KAJ7318921.1, hypothetical protein OS493_036793 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q2KHZ8	Lysosomal acid glucosylceramidase OS=Bos taurus OX=9913 GN=GBA1 PE=2 SV=1
P17439	Lysosomal acid glucosylceramidase OS=Mus musculus OX=10090 GN=Gba1 PE=1 SV=1
P04062	Lysosomal acid glucosylceramidase OS=Homo sapiens OX=9606 GN=GBA1 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003972 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02055 all species →	Glyco_hydro_30	Glycosyl hydrolase family 30 TIM-barrel domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR017853 all species →	Homologous_superfamily	Glycoside hydrolase superfamily	Interproscan
IPR001139 all species →	Family	Glycoside hydrolase family 30	Interproscan
IPR033453 all species →	Domain	Glycosyl hydrolase family 30, TIM-barrel domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11069 all species →	GLUCOSYLCERAMIDASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004348 all species →	Molecular Function	glucosylceramidase activity	Interproscan
GO:0006665 all species →	Biological Process	sphingolipid metabolic process	Interproscan
GO:0006680 all species →	Biological Process	glucosylceramide catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01201	GBA, srfJ; glucosylceramidase	EC:3.2.1.45	Lysosome	ko04142	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_036793-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

105TPM > 0

7Conditions

6.9Max TPM

2.3Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	1.89	3.84
polyp at pH7 6	18	16	1.63	2.37
coral polyp · control treatment	16	16	3.49	5.92
coral polyp · oil and dispersant treatment	16	15	2.18	4.51
coral polyp · oil treatment	16	16	3.26	6.88
coral polyp · dispersant treatment	16	15	2.21	4.66
Polyp	10	9	1.00	2.31

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.84
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.20
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.50
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.37
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.21
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.15
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.06
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.01
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.97
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.94
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.91
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.57
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.53
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.17
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	1.10
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.91
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.90
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.73
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.37
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.32
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.19
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.07
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.05
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.04
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.04
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.00
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.98
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.90
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.86
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.85
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.82
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	1.44
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.76
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.72
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.92
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.91
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.73
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.56
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.67
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.51
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.07
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.64
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.09
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.78
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.68
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.64
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.87
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.14
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.10
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	0.53
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.51
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.34
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.92
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.88
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.53
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.32
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.16
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.84
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.81
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.73
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.72
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.25
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.14
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	1.08
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.63
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	0.00
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.88
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.84
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.58
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.25
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.21
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.31
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.31
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.97
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.60
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.52
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.26
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.25
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.51
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.25
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.77
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.62
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.66
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.15
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.56
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.26
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.24
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.00
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.86
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.19
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.96
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.77
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.20
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.16
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.08
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.82
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.38
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.00
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	2.31
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	1.70
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	1.46
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	1.31
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	1.29
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	0.74
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	0.59
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	0.37
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	0.27
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.