Gene detail

Detailed information of OS493_037412-T1 in Lophelia pertusa

Genomic Location: scaffold_422:199763...206853
NR annotation: KAJ7382076.1, Mitogen-activated protein kinase kinase kinase 7, partial [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A2VDU3	Mitogen-activated protein kinase kinase kinase 7 OS=Bos taurus OX=9913 GN=MAP3K7 PE=2 SV=1
Q62073	Mitogen-activated protein kinase kinase kinase 7 OS=Mus musculus OX=10090 GN=Map3k7 PE=1 SV=1
O43318	Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003270 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR017421 all species →	Family	Mitogen-activated protein (MAP) kinase kinase kinase 7-like	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46716 all species →	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0000287 all species →	Molecular Function	magnesium ion binding	Interproscan
GO:0004709 all species →	Molecular Function	MAP kinase kinase kinase activity	Interproscan
GO:0006955 all species →	Biological Process	immune response	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0007254 all species →	Biological Process	JNK cascade	Interproscan
GO:0043123 all species →	Biological Process	positive regulation of canonical NF-kappaB signal transduction	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04427	MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7	EC:2.7.11.25	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_037412-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

105TPM > 0

7Conditions

26.8Max TPM

7.9Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	7.03	13.78
polyp at pH7 6	18	16	6.02	13.38
coral polyp · control treatment	16	16	11.89	26.76
coral polyp · oil and dispersant treatment	16	16	10.30	25.98
coral polyp · oil treatment	16	16	9.30	21.66
coral polyp · dispersant treatment	16	15	6.78	13.30
Polyp	10	8	2.23	6.05

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.78
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.81
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.47
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.05
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.07
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.51
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.37
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.28
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.61
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.54
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.77
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.70
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.61
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.89
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.68
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.39
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	2.04
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	0.89
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.38
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.94
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.24
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.68
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.63
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.57
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.95
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.07
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.86
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.85
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.63
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.52
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.75
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.59
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.11
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	2.57
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	0.00
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	26.76
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	24.43
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	22.76
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	19.76
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	18.53
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	16.82
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.38
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.44
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.78
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.30
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.05
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.36
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.65
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.35
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.63
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	1.21
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	25.98
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	20.75
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	15.51
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.74
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.04
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	12.46
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.87
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.64
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.81
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.79
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.23
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.85
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.71
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.54
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.87
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.07
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.66
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.81
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.91
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.09
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.48
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.35
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.88
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.16
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.52
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.28
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.25
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	3.90
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.14
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.11
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.00
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.24
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.30
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.30
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.53
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.14
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	9.77
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	9.37
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.07
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.78
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.87
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.99
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.28
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.70
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.29
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.10
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.06
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.00
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	6.05
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	5.30
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	2.71
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	2.24
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	1.82
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	1.58
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	1.53
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	1.05
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	0.00
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.