Gene detail

Detailed information of OS493_038261-T1 in Lophelia pertusa

Genomic Location: scaffold_542:44907...56039
NR annotation: KAJ7381928.1, Nitrogen permease regulator-like 2 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5E9U9	GATOR1 complex protein NPRL2 OS=Bos taurus OX=9913 GN=NPRL2 PE=2 SV=1
Q9WUE4	GATOR1 complex protein NPRL2 OS=Mus musculus OX=10090 GN=Nprl2 PE=1 SV=1
Q8WTW4	GATOR1 complex protein NPRL2 OS=Homo sapiens OX=9606 GN=NPRL2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004186 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF06218 all species →	NPR2	Nitrogen permease regulator 2	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR009348 all species →	Family	Nitrogen permease regulator 2-like	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12991 all species →	NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005096 all species →	Molecular Function	GTPase activator activity	Interproscan
GO:0005774 all species →	Cellular Component	vacuolar membrane	Interproscan
GO:0010508 all species →	Biological Process	positive regulation of autophagy	Interproscan
GO:0034198 all species →	Biological Process	cellular response to amino acid starvation	Interproscan
GO:1904262 all species →	Biological Process	negative regulation of TORC1 signaling	Interproscan
GO:1990130 all species →	Cellular Component	GATOR1 complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K20405	NPRL2, NPR2; nitrogen permease regulator 2	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_038261-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

109TPM > 0

7Conditions

37.4Max TPM

10.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	11.25	16.00
polyp at pH7 6	18	18	12.54	16.20
coral polyp · control treatment	16	16	12.87	37.37
coral polyp · oil and dispersant treatment	16	16	9.29	35.12
coral polyp · oil treatment	16	16	10.93	20.00
coral polyp · dispersant treatment	16	16	6.90	12.07
Polyp	10	9	7.79	24.71

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.00
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.12
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.86
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.84
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.12
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.64
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.02
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	11.19
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.83
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.73
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.35
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.11
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.97
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.23
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.95
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.78
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.63
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.10
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	16.20
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.18
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	14.61
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	14.40
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.95
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.82
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.71
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.68
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.53
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	12.37
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	12.07
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.69
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.12
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.99
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.07
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.07
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.87
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.38
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	37.37
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	22.10
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	19.42
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	16.28
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.07
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.52
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.01
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.68
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.45
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.09
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.78
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.54
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.86
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.74
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.08
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	3.99
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	35.12
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	14.88
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	12.65
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.23
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.67
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.92
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.92
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.95
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.87
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.47
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.20
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.06
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.51
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.86
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.82
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.60
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	20.00
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	19.89
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	19.66
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.97
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.93
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.18
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.41
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.18
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.56
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.51
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.27
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.43
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.31
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.83
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.57
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.17
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.07
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.85
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.08
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.03
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.75
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.60
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.60
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.53
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.13
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.98
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.89
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.38
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.51
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.90
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	2.49
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.56
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	24.71
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	9.36
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	9.28
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	7.79
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	7.11
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	5.44
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	5.22
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	5.17
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	3.85
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.