Genomic Location: NC_058071.1:3795519...3843199
NR annotation: XP_029194003.1, serine/threonine-protein kinase mTOR-like [Acropora millepora]
Species Acropora millepora · all data for this species · gene families
| CDS |
| XP_029194003.1 |
| Protein |
| XP_029194003.1 |
| UniProt accession | Description |
|---|---|
| P42345 | Serine/threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 |
| P42346 | Serine/threonine-protein kinase mTOR OS=Rattus norvegicus OX=10116 GN=Mtor PE=1 SV=1 |
| Q9JLN9 | Serine/threonine-protein kinase mTOR OS=Mus musculus OX=10090 GN=Mtor PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003065 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02259 all species → | FAT | FAT domain | Repeat | Interproscan |
| PF02260 all species → | FATC | FATC domain | Family | Interproscan |
| PF08771 all species → | FRB_dom | FKBP12-rapamycin binding domain | Domain | Interproscan |
| PF00454 all species → | PI3_PI4_kinase | Phosphatidylinositol 3- and 4-kinase | Family | Interproscan |
| PF11865 all species → | DUF3385 | Domain of unknown function (DUF3385) | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003152 all species → | Domain | FATC domain | Interproscan |
| IPR036940 all species → | Homologous_superfamily | Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily | Interproscan |
| IPR011989 all species → | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR000403 all species → | Domain | Phosphatidylinositol 3-/4-kinase, catalytic domain | Interproscan |
| IPR016024 all species → | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR003151 all species → | Domain | PIK-related kinase, FAT | Interproscan |
| IPR018936 all species → | Conserved_site | Phosphatidylinositol 3/4-kinase, conserved site | Interproscan |
| IPR014009 all species → | Domain | PIK-related kinase | Interproscan |
| IPR021133 all species → | Repeat | HEAT, type 2 | Interproscan |
| IPR050517 all species → | Family | DNA Damage Response and Repair Kinase | Interproscan |
| IPR009076 all species → | Domain | FKBP12-rapamycin binding domain | Interproscan |
| IPR024585 all species → | Domain | Serine/threonine-protein kinase mTOR domain | Interproscan |
| IPR036738 all species → | Homologous_superfamily | FKBP12-rapamycin binding domain superfamily | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR026683 all species → | Domain | Serine/threonine-protein kinase TOR, catalytic domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11139 all species → | ATAXIA TELANGIECTASIA MUTATED ATM -RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0016301 all species → | Molecular Function | kinase activity | Interproscan |
| GO:0004674 all species → | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| GO:0016242 all species → | Biological Process | negative regulation of macroautophagy | Interproscan |
| GO:0031929 all species → | Biological Process | TOR signaling | Interproscan |
| GO:0031931 all species → | Cellular Component | TORC1 complex | Interproscan |
| GO:0031932 all species → | Cellular Component | TORC2 complex | Interproscan |
| GO:0044877 all species → | Molecular Function | protein-containing complex binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K07203 | MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR | EC:2.7.11.1 | Membrane trafficking | ko04131 | deepkoala |
Transcript abundance of XP_029194003.1 across 54 RNA-seq samples of Acropora millepora. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole larvae | 30 | 0 | 0.00 | 0.00 | |
| branch | 24 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR1929605 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929606 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929607 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929608 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929609 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929610 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929611 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929612 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929613 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929614 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929615 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929616 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929617 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929618 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929619 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929620 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929621 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929622 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929623 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929624 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929625 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929626 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929627 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929628 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929629 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929630 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929631 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929632 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929633 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929634 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929581 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929582 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929583 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929584 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929585 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929586 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929587 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929588 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929589 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929590 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929591 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929592 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929593 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929594 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929595 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929596 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929597 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929598 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929599 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929600 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929601 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929602 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929603 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929604 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (AMILL_TPM,
StringTie quantification over 54 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora millepora tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Acropora millepora network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora millepora, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
| Dataset | Tissue / stage | Cells | Cell types | This gene | Marker of |
|---|---|---|---|---|---|
| AMILL_whole_adult | Whole adults · Adult tissues/organs | 25,164 | 27 | not in this dataset | – |
A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Sample | Methylation profile |
|---|---|
| planula | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
