Genomic Location: NC_058078.1:3088741...3096714
NR annotation: XP_029207418.1, eukaryotic translation initiation factor 5-like [Acropora millepora]
Species Acropora millepora · all data for this species · gene families
| CDS |
| XP_029207418.1 |
| Protein |
| XP_029207418.1 |
| UniProt accession | Description |
|---|---|
| P59325 | Eukaryotic translation initiation factor 5 OS=Mus musculus OX=10090 GN=Eif5 PE=1 SV=1 |
| Q07205 | Eukaryotic translation initiation factor 5 OS=Rattus norvegicus OX=10116 GN=Eif5 PE=1 SV=1 |
| P55010 | Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0008031 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01873 all species → | eIF-5_eIF-2B | Domain found in IF2B/IF5 | Family | Interproscan |
| PF02020 all species → | W2 | eIF4-gamma/eIF5/eIF2-epsilon | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002735 all species → | Domain | Translation initiation factor IF2/IF5 domain | Interproscan |
| IPR045196 all species → | Family | Translation initiation factor IF2/IF5 | Interproscan |
| IPR003307 all species → | Domain | W2 domain | Interproscan |
| IPR016190 all species → | Homologous_superfamily | Translation initiation factor IF2/IF5, zinc-binding | Interproscan |
| IPR016189 all species → | Homologous_superfamily | Translation initiation factor IF2/IF5, N-terminal | Interproscan |
| IPR016024 all species → | Homologous_superfamily | Armadillo-type fold | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23001 all species → | EUKARYOTIC TRANSLATION INITIATION FACTOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003743 all species → | Molecular Function | translation initiation factor activity | Interproscan |
| GO:0006413 all species → | Biological Process | translational initiation | Interproscan |
| GO:0001731 all species → | Biological Process | formation of translation preinitiation complex | Interproscan |
| GO:0001732 all species → | Biological Process | formation of cytoplasmic translation initiation complex | Interproscan |
| GO:0005092 all species → | Molecular Function | GDP-dissociation inhibitor activity | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0071074 all species → | Molecular Function | eukaryotic initiation factor eIF2 binding | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K03262 | EIF5; translation initiation factor 5 | - | Translation factors | ko03012 | deepkoala |
Transcript abundance of XP_029207418.1 across 54 RNA-seq samples of Acropora millepora. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole larvae | 30 | 0 | 0.00 | 0.00 | |
| branch | 24 | 1 | 14.84 | 356.16 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR1929605 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929606 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929607 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929608 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929609 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929610 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929611 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929612 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929613 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929614 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929615 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929616 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929617 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929618 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929619 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929620 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929621 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929622 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929623 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929624 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929625 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929626 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929627 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929628 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929629 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929630 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929631 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929632 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929633 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929634 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929602 | branch | branch | adult | not recorded | SRP056536 | 356.16 |
| SRR1929581 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929582 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929583 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929584 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929585 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929586 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929587 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929588 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929589 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929590 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929591 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929592 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929593 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929594 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929595 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929596 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929597 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929598 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929599 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929600 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929601 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929603 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929604 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (AMILL_TPM,
StringTie quantification over 54 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora millepora tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 121 | XP_044171719.1 | 1 |
| Negatively correlated | 3 | XP_044182638.1 | -0.254739898889763 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora millepora, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
| Dataset | Tissue / stage | Cells | Cell types | This gene | Marker of |
|---|---|---|---|---|---|
| AMILL_whole_adult | Whole adults · Adult tissues/organs | 25,164 | 27 | not in this dataset | – |
A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Sample | Methylation profile |
|---|---|
| planula | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
