Genomic Location: NW_025322773.1:420644...439509
NR annotation: XP_044169176.1, uncharacterized protein LOC114976684 isoform X1 [Acropora millepora]
Species Acropora millepora · all data for this species · gene families
| CDS |
| XP_044169176.1 |
| Protein |
| XP_044169176.1 |
| UniProt accession | Description |
|---|---|
| Q02858 | Angiopoietin-1 receptor OS=Mus musculus OX=10090 GN=Tek PE=1 SV=2 |
| Q91147 | Fibroblast growth factor receptor 2 OS=Notophthalmus viridescens OX=8316 GN=FGFR2 PE=2 SV=1 |
| Q02763 | Angiopoietin-1 receptor OS=Homo sapiens OX=9606 GN=TEK PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001005 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF07714 all species → | PK_Tyr_Ser-Thr | Protein tyrosine and serine/threonine kinase | Domain | Interproscan |
| PF07645 all species → | EGF_CA | Calcium-binding EGF domain | Domain | Interproscan |
| PF01390 all species → | SEA | SEA domain | Family | Interproscan |
| PF13927 all species → | Ig_3 | Immunoglobulin domain | Domain | Interproscan |
| PF00041 all species → | fn3 | Fibronectin type III domain | Domain | Interproscan |
| PF17517 all species → | IgGFc_binding | IgGFc binding protein | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR020635 all species → | Domain | Tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR013783 all species → | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR000082 all species → | Domain | SEA domain | Interproscan |
| IPR007110 all species → | Domain | Immunoglobulin-like domain | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR050122 all species → | Family | Receptor Tyrosine Kinase | Interproscan |
| IPR036364 all species → | Homologous_superfamily | SEA domain superfamily | Interproscan |
| IPR001245 all species → | Domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR049883 all species → | Domain | NOTCH1 EGF-like calcium-binding domain | Interproscan |
| IPR036116 all species → | Homologous_superfamily | Fibronectin type III superfamily | Interproscan |
| IPR000152 all species → | PTM | EGF-type aspartate/asparagine hydroxylation site | Interproscan |
| IPR003961 all species → | Domain | Fibronectin type III | Interproscan |
| IPR003598 all species → | Domain | Immunoglobulin subtype 2 | Interproscan |
| IPR003599 all species → | Domain | Immunoglobulin subtype | Interproscan |
| IPR017441 all species → | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR000742 all species → | Domain | EGF-like domain | Interproscan |
| IPR036179 all species → | Homologous_superfamily | Immunoglobulin-like domain superfamily | Interproscan |
| IPR018097 all species → | Conserved_site | EGF-like calcium-binding, conserved site | Interproscan |
| IPR000719 all species → | Domain | Protein kinase domain | Interproscan |
| IPR001881 all species → | Domain | EGF-like calcium-binding domain | Interproscan |
| IPR035234 all species → | Domain | IgGFc-binding protein, N-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24416 all species → | TYROSINE-PROTEIN KINASE RECEPTOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004713 all species → | Molecular Function | protein tyrosine kinase activity | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| GO:0004714 all species → | Molecular Function | transmembrane receptor protein tyrosine kinase activity | Interproscan |
| GO:0005887 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007169 all species → | Biological Process | cell surface receptor protein tyrosine kinase signaling pathway | Interproscan |
| GO:0007275 all species → | Biological Process | multicellular organism development | Interproscan |
| GO:0033674 all species → | Biological Process | positive regulation of kinase activity | Interproscan |
| GO:0043235 all species → | Cellular Component | receptor complex | Interproscan |
| GO:0004672 all species → | Molecular Function | protein kinase activity | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
XP_044169176.1.Transcript abundance of XP_044169176.1 across 54 RNA-seq samples of Acropora millepora. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole larvae | 30 | 0 | 0.00 | 0.00 | |
| branch | 24 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR1929605 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929606 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929607 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929608 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929609 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929610 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929611 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929612 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929613 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929614 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929615 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929616 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929617 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929618 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929619 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929620 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929621 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929622 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929623 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929624 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929625 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929626 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929627 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929628 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929629 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929630 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929631 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929632 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929633 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929634 | whole larvae | whole larvae | adult | not recorded | SRP056536 | 0.00 |
| SRR1929581 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929582 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929583 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929584 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929585 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929586 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929587 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929588 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929589 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929590 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929591 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929592 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929593 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929594 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929595 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929596 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929597 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929598 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929599 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929600 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929601 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929602 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929603 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
| SRR1929604 | branch | branch | adult | not recorded | SRP056536 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (AMILL_TPM,
StringTie quantification over 54 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora millepora tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Acropora millepora network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora millepora, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
| Dataset | Tissue / stage | Cells | Cell types | This gene | Marker of |
|---|---|---|---|---|---|
| AMILL_whole_adult | Whole adults · Adult tissues/organs | 25,164 | 27 | not in this dataset | – |
A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Sample | Methylation profile |
|---|---|
| planula | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |