Gene detail

Detailed information of XP_044170959.1 in Acropora millepora

Genomic Location: NC_058067.1:6278739...6307378
NR annotation: XP_044170959.1, disintegrin and metalloproteinase domain-containing protein 12-like [Acropora millepora]
Species Acropora millepora · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_044170959.1

ATGAGGGCGGCCAAGAACAGGCTGTTGGGCGCTTTTGTCTTTTGTGTTGTGATCTGTTTCTTCACAATTGTTGTTGGAGCATTGGATGGTAATCAAATAACTTATCCAGAACGAATTGATGGAAAACGACCGAGAAGTGACCTATCGACGTCTGGAAAGGGAGGTCACGTGCATGACGTTTCGTACCGATTGACAGCTTTTGACAAGGATTGGACTCTGGATTTAAAGAACAACAAGAAAATTATTTCGCCGTCATTTGCTATGCGTACGTTTGATGAAAACGGCTTAGAAAACATAGAAGAGGCTGTTTACGATGACTGTCATTATCAAGGGACCATTCGTGGAGTAAAGGATTCCAGTGTTGTCCTCAATACCTGTAAAGGACTAAGGGGAGTTCTTGACGATGGTAAAGATACCTTCCATATTGAACCTGTGTCAGGCTACAAGAATGGAGCCCACAGCGTTTTTCAAACCAAAGAACAGGACTCAAGCGACGTCTACAAAGGCTGTGGAAATGAAGATGTCTTCACAGAATATCATGTTTCTGAGGACACTTTTGGACACTTTTCCACGATTCGACGAGGTATCTCAAACATGGATGATTTCTATAGACCATACATGACGACCAATGAAACACGATACAACGAACTTGTCTTGGTAGCAGATCATCGAATGTACCTCGAGCACAACAATGATACTGCCACCATCAAAGACAGAGTTATTACATTGGTGAATGCTGTTGATGCGATTTATCAGCGAATCAACATCAGGGTTGTTCTCAAGGCACTAGAGATCTGGACAAATGGTGATCCATACGAGCGAGAGATCAAAGGAGGACCTGATCTTGTCAAGTTCAATAGCTATCGTAACGCGCATCTTCAAGACAAATTTCCTCATGATAACGCCCAGTTGTTAAGCCAATGGGCGTGGTCGGACTGTGCAGGCATGGCTTTCGTAAGATCAATGTGTGGTCGCCATTCAGCTGGTGTCAACAGGTGGAGTATGAGAAGCATCATTGGTCCTTATGTTACGGTTGCTCACGAAATGGGCCACAACTTCGGATTCAATCATGACTCGGGAAATTGCAAATGTTTAACACCCCGAGGATGCATCATGGGTGGACACAAAACGAGGGTTCCAGGATTTTCGAACTGTAGCTTGGCTTCTCTAAAGAAGATCAATGACAAGTGTCTTTTCAACGTTCCAACATACCAGGCTCTAAACAGTTACTGTGGCAACGGCATCCGAGAAGAGGGAGAGGAATGCGATTGCGGTACACCTGAGATTTGTAAAGCTAAAGATCATTGTTGTGAGCCTCATAACTGTGTTCTTAAGAGTAGCTCTCAATGCAGTGATTTACACCACGGATGCTGCGAGAACTGTCTGTTTAAGAAACAAGGTACCTTATGTCGAGGAGTCAAAACTGATTGTGATGTACCTGAATACTGCACCGGAGGTTCTAGAGATTGCCCAGCAGATAGCTATATTTATGATGGATTCCAATGCAATCAAACTAAAACGGTTGTCCAAGGAAGTATCAATTACAATAGCGTGTTTAAAAGGCAGTTGAATCCAAGACCTAACACTCGATATCTTCGCCTCAGTCCTCAATACTGGCACGGTTGGCCTTGTTTAAGAGTTGACTTTCTGGGGTGCTCTAAAGACGAAGTCCATCCAACCGCTCCAACACCACTCAAATCTTACCAACTCAATGATCTCTGCCTCACACCCTCCAACAAGACCTGTTCGCCGAATGATAATGAAAATATCATTTATGCACGGGGTGACAAGTGTGATGGAAAACATTTCCAGTTCACATTGGAGTCAAATGGTGTGTTACGTCACAGCTGCAGTGGAAAGATGGTTTGTCCCACAGGAAGTGGAAATGGTGCGAACCTTGTCGTCAGCAGTAGCTGCCTAACAAGTAACTCCAAATTTGAGAGGACTCAGGGGCACTCACTGAAGCACTTGAAAACGGGAAAATGCATCCACACACATGGTGGATGGCCTGGGGAAGACAAAAAGATGGTACTATGGTCTCTTTGTGATGAAACGAGGCTGGAAATATGGTTTGTGAAACAAGATTGCGTGGATCGCCTAGGAATGGAAAGTGGTTACATTTTAGACAATCAGATCACGGCAAGCTCCTATCGACCTGCAGATTTACCACAATATGGAAGGCTACACAATAATAAGTATTGGTGCGCTGGCAAAAACAGTAAAGATGAATATTTTCAAGTAGATCTTGGCCAGGAAAAAACTGTCAATGAGATCTTGATTCAAGGACGCTCAAACTGGTATAACTGGGTGACTGGATTTCACCTCTACTTCAGTGACGATGGACATCAATGGACTGGCTACTCGCGAAGTGGAGATAAAAATCATTCCAACTCTGTATGTTACCTTGGCGAATGCAGCGAGATTCATGAAACTCAATGCAAAGATCTCTGGGGATCAGCTGCAAGAAATGCCGATCAAGGATGTTATACAAAACTTAATACCGAATTATCCGGGTATGGGACATGTGATCCAACGACAAATATATCATGCGCTTTGAGGGACGTTTTATGTGGCCAGCTGCAATGCGAAGACAAAGCAAATTCACCTGTTGCTGATTATGGGTGGAGTTACAAGAAGATCATCTTGGACAACGGAAAAATGTGCAATACCGCCACCTTAAAATCTAGTGACTCCACTGGACTGGGAATGGTCAGAGATGGAACAAAATGCGACACTAATAAGATTTGTGTTAATTTCAAGTGCCAGAGTTATGATCAGCTCAATATAAGCAAATGTCCTTCAGTAGCTGGTGAAGAATGCGGGGGCAGAGGGGTCTGTACAAATGAAGGGAAATGTTACTGCGAAGACGGATTTGATCCAAAGGATTCTTGTTCTTCTGTGACCGTGCCTCGAGATGGAGCATGGGGAGAGTGGTCTTCTTGGACTGTGTGTGACAAAGGTTGCGGAAGTGGAAAACGGGAAAGACATCGCTTTTGCGACAATCCGTTTCCTTTGCATGGAGGAAAGGATTGTCCAGGTCATCGACAGGAAACGGAAGATTGCAATACAGAAAACTGCCCAGTTGGGATTTCATGCCGACACTTGCAACAGATCGGCCAAGAAAAGAACCGTGATTATCCTGATGGCGTCTACAAGATAAATCCGACAGGCTCTGAAGAAATTTCAACTTATTGTGACATGTCACGTGACGGTGGCGGATGGACGCTATTAGTGGCTAGTCATACTAATTCCTGGACTAAACGTAATGTGTATTTAAGGAACGAAAACACCCCAACATTGAATGATGACTTCTCCATTCTCGAGCACGCAGACAACATCAAGAATAACATCAACGTTGCTGGATCAAGGTTTGAATATCGATTGGAAGCGCAAAAGCCAGGTACTAATTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A3R0T9	Zinc metalloproteinase-disintegrin-like ohanin OS=Ophiophagus hannah OX=8665 PE=1 SV=1
Q61824	Disintegrin and metalloproteinase domain-containing protein 12 OS=Mus musculus OX=10090 GN=Adam12 PE=1 SV=2
Q2UXQ5	Zinc metalloproteinase-disintegrin-like EoVMP2 OS=Echis ocellatus OX=99586 GN=Svmp3-Eoc22 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000540 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01421 all species →	Reprolysin	Reprolysin (M12B) family zinc metalloprotease	Domain	Interproscan
PF00754 all species →	F5_F8_type_C	F5/8 type C domain	Domain	Interproscan
PF08516 all species →	ADAM_CR	ADAM cysteine-rich	Family	Interproscan
PF01562 all species →	Pep_M12B_propep	Reprolysin family propeptide	Family	Interproscan
PF00200 all species →	Disintegrin	Disintegrin	Domain	Interproscan
PF00090 all species →	TSP_1	Thrombospondin type 1 domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001590 all species →	Domain	Peptidase M12B, ADAM/reprolysin	Interproscan
IPR008979 all species →	Homologous_superfamily	Galactose-binding-like domain superfamily	Interproscan
IPR034027 all species →	Domain	Reprolysin domain, adamalysin-type	Interproscan
IPR000421 all species →	Domain	Coagulation factor 5/8 C-terminal domain	Interproscan
IPR035992 all species →	Homologous_superfamily	Ricin B-like lectins	Interproscan
IPR006586 all species →	Domain	ADAM, cysteine-rich domain	Interproscan
IPR036056 all species →	Homologous_superfamily	Fibrinogen-like, C-terminal	Interproscan
IPR000884 all species →	Repeat	Thrombospondin type-1 (TSP1) repeat	Interproscan
IPR036383 all species →	Homologous_superfamily	Thrombospondin type-1 (TSP1) repeat superfamily	Interproscan
IPR024079 all species →	Homologous_superfamily	Metallopeptidase, catalytic domain superfamily	Interproscan
IPR001762 all species →	Domain	Disintegrin domain	Interproscan
IPR002181 all species →	Domain	Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain	Interproscan
IPR014716 all species →	Homologous_superfamily	Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1	Interproscan
IPR002870 all species →	Domain	Peptidase M12B, propeptide	Interproscan
IPR000742 all species →	Domain	EGF-like domain	Interproscan
IPR036436 all species →	Homologous_superfamily	Disintegrin domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11905 all species →	ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004222 all species →	Molecular Function	metalloendopeptidase activity	Interproscan
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0008237 all species →	Molecular Function	metallopeptidase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for XP_044170959.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_044170959.1 across 54 RNA-seq samples of Acropora millepora. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

54Samples

4TPM > 0

2Conditions

25.7Max TPM

1.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
whole larvae	30	3	1.75	25.68
branch	24	1	0.15	3.72

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR1929618	whole larvae	whole larvae	adult	not recorded	SRP056536	25.68
SRR1929633	whole larvae	whole larvae	adult	not recorded	SRP056536	20.93
SRR1929606	whole larvae	whole larvae	adult	not recorded	SRP056536	5.85
SRR1929605	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929607	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929608	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929609	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929610	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929611	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929612	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929613	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929614	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929615	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929616	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929617	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929619	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929620	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929621	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929622	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929623	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929624	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929625	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929626	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929627	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929628	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929629	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929630	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929631	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929632	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929634	whole larvae	whole larvae	adult	not recorded	SRP056536	0.00
SRR1929599	branch	branch	adult	not recorded	SRP056536	3.72
SRR1929581	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929582	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929583	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929584	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929585	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929586	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929587	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929588	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929589	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929590	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929591	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929592	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929593	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929594	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929595	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929596	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929597	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929598	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929600	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929601	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929602	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929603	branch	branch	adult	not recorded	SRP056536	0.00
SRR1929604	branch	branch	adult	not recorded	SRP056536	0.00

Source: CnidoSite RNA-seq expression matrices (AMILL_TPM, StringTie quantification over 54 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.