Gene detail

Detailed information of XP_044173236.1 in Acropora millepora

Genomic Location: NC_058067.1:32673869...32699295
NR annotation: XP_044173236.1, eukaryotic translation initiation factor 2-alpha kinase 3-like [Acropora millepora]
Species Acropora millepora · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_044173236.1

ATGAACATTTTCCATGCCACGGTACTGACTAAGTTGGTCGCTTTTATGGCGGCGTTAGTCTTTGTTGACGGAGAGTTGGAGGGCACCAAGCCAAGCGATCTGCCCTCTCGGAGAAGCTCATGTTCTTTGGTTGTTGTGAGTACACTGGATGGCAAAGTTAGCGCTTTGGACACAAAAGACAATGGCAAACTACTTTGGACTCTACCCCCTTTTCACGGTCCACTGTTGTCATCGAGTCTTAGTTCAATTCAGATGGCAAAGCATGTTGGCCTGATTCCGTCACTTGATGGTGGACTTTATCAATTTGATGGGGACAAAGTAGAGCCCATTCCTTTCACTGCTGAATCACTTCTTGGCTCATTTTACAAACTCCCAGATGGATCTATCTTGGTTGGTGGCAAGGAGGCAACCTCTTGTGGAATTAGTCCTTCTTCTGGAACAGTGCGTTATGTGTGTTCTGCTGATGGTTGTCAATTGGCAAAGCCTGAGGAAAGCAGCATCAACAATGACCAAGTTCTAGTGCTCAAACGCATACAGCAAACCATTAGAGCTGTGGATCAGAGAACGGGAGTTGAAAGATGGAACTTTTCTGTAGGACAGCATGACATTAGCTTTCTGGAGGCCATTTTTAGCGATGATGACGACAGCAAATGTTCATCCCAGGACGATGAAGAGTTTGTGGATTGGAACATTCGTGTGTCTATTTCCGGTGGTCTGGTTGCTGCAGTCCGCTCATATGGTTTAAAAGAAACTGAAGAAGTGTTATGGAGTCACCAGTTTGATGCTCCAATAGCTGCGGTATGGAGGTTGAATGGAGGGTACATTGAGCCAGTGAGCATTCTATCGCAAGAGGTTATGCCGCAACTTGTTGACTCCTCCTCCCAACAAGCTCTTCCTCAAGGTCCAGTTATGTATATAGGAAAACATGATGGTCAAGTCTACATTCAAACTTCAGAGTCCTTCACCCCTGCTCAGGAGAAGCCTGCACAATTTGGTGTTATCAGGGAAAAGAAAGCTGTACAGAGTATTAAATCTCAACAGATAACATGGCGGCCATACTTGACAAGCTCACCATCTCGCACCCCAACTGTTGTCACTAAAGACTTGGCTGTCTGGAATCCACTGGATTATCCATTTGACAATGGGTACTTCTTGTATGGGGAAGTGATGCCTGTGATTCCACCACACACTTGCAAGAATGACCAAAATATTATTTCAGAGGGTCAAGAAAACGTTTTTGACAGAGATGACAAAACTCCAGTTGCTCACTCTGATAGGTCATCATGGTGGTTTGGTGCAATATTTGTCACAGTGGCTTTTGCTGTTTTGCTCCAGTTTGTTATTCGTTTTTTCCACAATAGAAACAAGAAGAATGTGAGGGAATGTGGTGCGTTGATGCAGTTGCAGCGAATGCCATCCAAAGCATCAACTTCTTCCTTCGAGACTGTCATGGGACTTCCTTCACCTTCCACACGCGGTAGCTTAACATCAACAAATTCTTTTTCCTCAAGGTATTTAACAGACTTTGAGCATGAGTGCTGCCTTGGTAAAGGTGGTTTTGGAGTAGTTTTCCAGGCAAAGAACAAGCTAGATGACTGTCAATATGCCATAAAAATGATCCGCCTACCAAACTGTGATGAGGCCTTAGAGAAAGTTATGCGTGAAGTAAAAGCACTTGCCAAACTGGAGCATCCCAGCATTGTACGCTATTACAACACTTGGCGTGAGGCGCCTCCTGATGGATGGCAGGATGAAGTCTATGCAAAAATGTATGAAGAGGGCTCACCTTGGGGAATTTCCTCTGAAAGTCCCTCAAATGGTTCAGGGATTGAATTCAAGGCTGAATCTACAGATAATATCATTGATAGGAATGATATACAAAAAAATAAGTCAGGAAGGCAGAGAAGGAAAAAGACTTACTCAAGCAGCAAATCTTGGAATTCTTCACATAGTTCAATAATTGTTAAGGATGACTGCTCGGTTGAGGAAATTGGGAATGAAGAGTCAATTAATATTCACCAGTTTGAAAATGAAGCAATTTTGGCAGGTCATGAAATGAGTGACTCGTTTAGCGTAGAGTTTGCTTCTTCAAGCCACAAAGGCTTGACAACCAAGAAAAATGGATTCAACAAGGACCTAATAGTAGAAGATTGTGCATCTAACAGTATTATTTTCAAGGATTCTGATGCAAGTCATATTCAGGATGAGGGTGATATTAAATCCCATTCAACTGAGGAAGTTGAAAGCTCAAGTTCAAAGGATAAAGGCTTTTCAGATGAAATGCATTTCACTTCGTCACACCACTCCTTGCTTTCAAGAGAAAAGCACAAATGCCAAAACAAAAACTGCAGTGCAGAAAAACTATCAGCACCATTGTACGTGTTTATACAGATGCAGTTGTGTAAGACGGAGAGCTTAAAGGACTGGTTAAAAGCCAATTTTGAAAGAAACCACGTCTTTTGTATAAGAGTGTTTGAACAGATCCTAGATGCTGTGGAATACTTTCACGGACGAGGATTAATGCACCGAGATTTAAAGCCATCCAACATTTTCTTTTCGCTGGATGGATCAGTAAAAGTTGGTGATTTTGGACTGGTTACTGCTCACTCCTCTGAGAACAACATAGACATTTCTTTGAAAGGCACTCCGATGGATGACACAAACCACACCAGTCAAGTGGGAACTCAGTTATATATGAGTCCAGAACAGATAGATGGCGGGGTGTATTCACACAAAGTAGATATCTTTTCACTGGGACTGATCTTCTTTGAGTTATTTTGTCCGTTTGGAACTCAAATGGAAAGAATCAAGGTCATGGGTGGTGTAAAACAAAGAGTTCTCCCAGCAGATTTTACAGAGAAGATGCTGCTTCAGTCGGAATTGGTTCAGTGGCTTTTGTCCGCCTCTCCCATGGCAAGACCAAACGCCACAGAAGTAAAGAACAGCTACCTTCTAAAGCAAATCAGACACGCTATCACGCCAAGTAATACTGACAGCATTCGTTCAGTGACACATTAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9Z1Z1	Eukaryotic translation initiation factor 2-alpha kinase 3 OS=Rattus norvegicus OX=10116 GN=Eif2ak3 PE=1 SV=1
Q9Z2B5	Eukaryotic translation initiation factor 2-alpha kinase 3 OS=Mus musculus OX=10090 GN=Eif2ak3 PE=1 SV=1
Q9NZJ5	Eukaryotic translation initiation factor 2-alpha kinase 3 OS=Homo sapiens OX=9606 GN=EIF2AK3 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004196 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR050339 all species →	Family	Cell Cycle and Stress Response Kinase	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR018391 all species →	Repeat	Pyrrolo-quinoline quinone beta-propeller repeat	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR011047 all species →	Homologous_superfamily	Quinoprotein alcohol dehydrogenase-like superfamily	Interproscan
IPR015943 all species →	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11042 all species →	EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0004694 all species →	Molecular Function	eukaryotic translation initiation factor 2alpha kinase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08860	EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3	EC:2.7.11.1	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.