Gene detail

Detailed information of XP_044181861.1 in Acropora millepora

Genomic Location: NC_058074.1:604858...621225
NR annotation: XP_044181861.1, disks large homolog 5-like [Acropora millepora]
Species Acropora millepora · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_044181861.1

ATGTTAGCCATGGAGGAAGGTTATAAGAAATTGATAGAGCGACACAGGGATAGATTTAGAAGCGCAATAACGGTGGAAAGGCTCTTGGCTGCTCTTGTTTTCAGCCATGTTGTTAACTGCGAAGAAGCACAGCTACTTCAAAGCGAACATCCTACGCAACGAGTGGACCGATTGTTAGATGTCATTCAAAGGAAAGACTATGAAACATTCAAGAAGTTCTGTGTGGTTTTAGAGAGCACATATCCTTACATGTTGAATTGTATGTTCCTCGGAGTTGAGCCCCCGACAAGCAAAACAACTGTCACACCTCATCTCAGGGCGGACCAAAACCAAGCTACAGATAATTCAGACGACAGTTCTCGTCATATTCAATGCATGGGTCCAGCACATCGAGTCAGTGTTGGACGGAGTATAAGCATGGTAGGTCACCAGGATCGTGTTCTCATGCTGAGAAATGAGCTGAAGACGGTCAGACAAGATTTGGAAAGAGTTTCAACACAGTTGCTAAAAACAGAAGCAGAACGGGATGCTTATAAGAAAATTATTGATCTTGAAACAGGAGATTCAGAGAAGAACTCGAATTCAGCAATTGGAAAGTTGCAGGAAAATGACAGAGATAATGAATTTGAACGTCTTAAAAAGCAGTATGTTGAAAACCTAAGAGAGCTTGAAATGTTGCGATATGAGAATTCTGGAATCTCAGAAAAGTATGAGGAAGTCTGTCAACAGTGTGAAAATAATCGGAAATACAAAACACTGTATCAGAATTTACAAAGACGGTTTGAGCAAATTAACATGGAGCGCAACAAACTCCAGCAGGAGTACGAAGAGATTGTTTTGCTGAGGGAGAGAGAAAAAATTGAAATGAAGGACAATCAACAGTATGAGAAATATCTCAAAAATCAAGCAGGGAATACTGGGTTTGATAAGTATGATTCTCACCAGAAAGATTTTGAAGGCCTTCAAGATGATTACAGAGATCTCAGGTCCAAATATAAGCTCTTATTTAACAGATTTCAAAACTTGGAAGGGGACTATTCAGCTTTAAAAATTCAATTTGATGACGTGCTGCATGAGCGCGAATCATTGCTAATGGAGAGAAATGGACTCAAACAACAATCTGATGCAGCAATAAAGAAATACGACAAAGCCATGAAAGATTGTGAAATTGCAATGAAGAAGTCAATTCAAGAAAAGCAACAGGCACAGCAGCAACGGGACTCTGCGCTGAGAGAATGTGATCAGGTAATGGCTCTTCAAGTGAAAACAGCAAAAGACATCACAAAGTTAACAGAGGAAAGGAATGCTGCTGTGAGTGAATATAAGTTAGTTATGAGTGAAAGAGACACCGTGCACCTTGAAATTGAAAATCTTCATGACGAGCTGTCAAATTTGCGTAAGACCAATGAAAACCTCAAGAGGGATTATGCAGACTTGCAGAACCACTTGGAAGATACACAAGGAGAAATCTCTCTCTTAGTGGAAGAACGCATGCAAGTGAACAAGGAGGTACAGAATCTAAAAGAAAGGCTACATTTGGCTGTGCTAGAAAAGGAGAGCCTTTTGAAGGAACAGAGGAAACTTAAGGAAGACAATGACATGTTTAAACAGGAGAGAAATGTTGCAAGAAAGGAACGTAGTGAAGCAATTATCCACAGAGATAAGATTTTGAAAGAATGCTTTGAGATTAAGCGAAAGCATCAACTTGCAATCAAAGGGGAAAATGAAAGTGAATCATTGAGAAAACAGTTTGATGCTCTTACAAAAGAACTGACTGATGCATTAAATAAGATTGAAGATGCAAAAAGGACAAGGGATTGTGCCTTAAATGATCGAGATAAAGTGACAAAAGAGTATGAGCTGCTGAAAATCAGATTTGACAAAATGCAGTCTGACAGGGATCAGGCAGTCAGTGAACTGGCAGACCTTCGCCATGAGTCTGAACACATTCAAAGGAAACATGCCGAAGCAGTAGCTGAGTTGTTTGAGCTGCGCAGTCACATTGAGGTGCAATTGAATCAAGGAAGTCTCTTATCAAGTAGGGATTCAGCTATTGACACTGACTGCAATGATTGGGAAACAGAGTCAGTTGTTCTAGAGAGGGTGAATTTGGATGATGATCTTGGAATTGCAATCGCTGGTGGAAAAGACAAACCTGCATTGCCTAACAGCAGCTCCATTGTTATAACTAATATTGCAAAAGGGAGCATTGCTGATGGAAAGCTCAGGGTGAATGACTGCGTTCTGAAGGTCAATAACACTGATTTGACGAACGTGGAATACTGCACTGCTGTTCAAGCAATCAGTCGTGGCGATGTCATAAACATGACTGTGAAGAGAAGGAGGTTAAATGGTTCCCACTCACTGCTTCATCCTGTTTTTTTAATTCTAAGAAACAATAAAGAGATGGGCATTCGAGTTGACAGTACAAGTCACATCACAGCCATTTTGCCTGGAAGTGCAGCAGCAGATGATGGAACAGTGGCTGTTGGAGATAGGATTGTAACTATTAATGGCACATCAGTCGAAAATCTCAGCAAAACTGAAGTTGAAAGTCTCTTGTCAACAAGCTTTCTAAACTTGACTGTTCAGAAATTGTCAGGAACCTCATCTCAAACCCAAGTACTTCAATCTCTTCTTGAGGAGATCAATGAGAAAATAATAAGGCAAGAAAATGACATTTGCCGGGAAGCTGAATTCACCAGGGAGAAAATAAGGAACTCAGGGAGTTTAAATGAGCTGCAGTTGTCTCAGCAGGAGTCATCTTCTGCATATTTCTCAGGAAAAAGCTCACCTCTACCTGATGACCAAATATCATCCACACCAGACTCTTTTTCTGAACCAGTTTTACATTCAACTTCTTCGTTGACTCCTCTTTATGAAGAGCGATTGAATGGAAAACAAACTGACTCGAGTGGTGACCTTTCCACCGAGGAAGGCAGTTCACCTCATCTTGGTGCAGCACCTCGCAGCCACTTCAAGTTTAGAAAACCTTTGGAGCGATCACGTCCGCTTACTCATTCACCTCGGTTTCCAATGCCTGTACAGTTATCACACAAGGAAAAACCAACACCTCCTGTACGAAGTCGTTCCTACATGTCTGCTATAACTTCACCAACGCATGAAATGTCCAACACAAGTTCTCAAGAAGATGACATGTACATGATGCCCTCACTGGGCCCGGCGTCACTATCAGACTCTTCACATCATGAAGCCAGTGAACCGACTGTGGTCATGCGGAAAAAAACTGAGTCATATTTTCGTAATACTGGTTTACGTCCTCAGTCAGCCCCTTCCTCAAGACATCACCAGGCTGTGTCAGGAAGTAGCCCTGTATTAAGCAGTTTTGAATGCTATTCTGCTAGCCATGGAGATCCCCTTGCACTTACTACATCCAAATCAAGTACTGTTGGCCATCCTGCAAGTGTGGCTGTTTTAAAATCAACACCTGTCCAATGTTATACTGCAAAAAGCCATTCATTGCATAGTTGTGAAGCACTTCCAGCTGAGAGCCAACAGTGTGTTCCTGTGCAGTGTAACAGCCGACAAAAACAGTCAAGATTGAAGGGAGATAGTCACACCACAGACCGGCACAGTCGGCAAGGCTCATATCACAGTGCAGAAGGAGGAAGTGAACATAATGGCCACCACTTCTGTGGCTATGAAACAGCATCAAAGTCAAAGCACAAGCTAAAACGAATCAGTTTGCCAAACTCTTCATCATATGTCCAATCTTCCAATGCAACAACATCCAGTTTTTGCAGCGCATCTGTTGGTTCAGCATACTCTACTTCATCAGGTCGCACCACACCAATAGTGATTCCGTCAACTCCAATTGTACCAGCCAATGAGGGTGGCCCTGCTTTGGCTTTTGACTTTAGTGGTCCACTGACATCAACAGAGGACCCTTTGAACAGGGATCATGAACCACGTCTTGTGCACATTGAAAAGAAAGATACACTAGGGATTTCCATTGCAGCAGCATGTCAGGGTGGGGTTATTGTCTCTTCCGTTACTGAGGGAAGTGTTGCTGCGAAAGCAGGACTCAAATATGGTGATCAGTTGCTAGAGTATAATGGTGTCAACTTGAGATGTGCGACATACGAGCAGGCAGCAATGATCCTAAAACAGTCTGGAAACAGTGTGACCATACTCGCGCAGTTTAATCCTGATAAGTTCAAAGACACGTCAGAATCTTTATCCAGCCAATCAGAAGCAAGCACCACATGCAGTACACCAGTCAATAGGAAGAAACACGAGAGCAGTAGCAGCACTCCACCAATCAGAAAGAAAGGCGAGATTCTACCAATCATTGACAACGAACCTCCGGGTGATCTGCGTTATGTATTCTTCACAAAGAGTCCAAGCTCATTAGGTTTCAGTATTACAGGTGGCAATGCTACTGGTATATTTGTATCAGAGATTCAAGCTGATGATGAGGCTGTTAAATCATCTGGACTCAGAGTTGGTGATCACTTGCTAGAACTTAATGGTGTGGATTTAACATCTGTGACTGCAGAGCAAGCCATGTTGGAGTTATGCAAGCCCACAGAGACAGTGCAAATATTACTTCAATATAATCCCACTAAATTCAACTCTCTCAGAGATCAACCAGGAGACTCTTTTTATGTCAGGGCCCTGTTTGATCGTACACAACACTTAAAAGATGAGCTGAGTTTCAAGAAGGGGGACATCCTTTATGTCACGGACACAATGTACAATGGCCACATGGGCTGTTGGAGAGCATGCCTTGTAAATGAAGAAGATGCACAGAGAAGGGAAATTGGAATGGTGCCAAGTCGAATGAAAGCCGAACAGGAGATTCTTTTACGCAGAAGTCTGGTTCATGGAGATGAGTACAAACTGAGTGGAAGAAGAAGCTTCTTTCGAAGAAGTAAAAAAGGCAGCCATGGAATGTCAGTGAACCATTCACGAGAGGGCAGTGACTCTGCCAACAGCATAACAACAAGCTGTACAGATCTAGGAATAGCTTCCTACCAAACAGTGGACAAACTAGACGGTCATATTCCAAGAGCAGTTATTTTGTTTGGTCCTTTAGTTGACGTTTTATATGACAAACTCTGCGAAGAGGTTCCGTACAAGTTTGTGCAGTGCAAGCCAGAAATAGTAAATCTTCCAGAGGAGACGGTAGAGAAAGGAGTGGCAGAAGGGACATTAGTTGATTATTCTTGGAAAGGACGTCAGCTCTCCTGCACAACAATGGCATCCATAAAACAAGTAGTTGACAAGCACTGCTTGTTGGACGTCACTCCATCAGCAGTGGAGAGGCTTCATGCGCTACAAGTTTACCCAATTATTTTGTTCATCAAGTTCAAATCTTCCAAACACATCAGGGATCAGAGAGATGGTAGATATGTCAGAGAAAAAATTAGCCACAGGCAAGCAAAAGATATACTGGAATCCATGGTGAAATTGGAACACGAGTTTAAACACCTTTTCAATGGAGTTGTTCATGGAGGCAGCATCAGCAACATGTGTTCGCAGATACAAGAGATGGTGGATGAGCAACAGAAAAAAGCAGTATGGGTCCCACTACCCAATGTCTAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8TDM6	Disks large homolog 5 OS=Homo sapiens OX=9606 GN=DLG5 PE=1 SV=4
E9Q9R9	Disks large homolog 5 OS=Mus musculus OX=10090 GN=Dlg5 PE=1 SV=1
A0A0G2K2P5	Tight junction protein ZO-1 OS=Rattus norvegicus OX=10116 GN=Tjp1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003808 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF07653 all species →	SH3_2	Variant SH3 domain	Domain	Interproscan
PF00595 all species →	PDZ	PDZ domain	Domain	Interproscan
PF00625 all species →	Guanylate_kin	Guanylate kinase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036034 all species →	Homologous_superfamily	PDZ superfamily	Interproscan
IPR001478 all species →	Domain	PDZ domain	Interproscan
IPR008144 all species →	Domain	Guanylate kinase-like domain	Interproscan
IPR001452 all species →	Domain	SH3 domain	Interproscan
IPR001315 all species →	Domain	CARD domain	Interproscan
IPR011029 all species →	Homologous_superfamily	Death-like domain superfamily	Interproscan
IPR053004 all species →	Family	MAGUK Family Regulators of Signaling Pathways	Interproscan
IPR036028 all species →	Homologous_superfamily	SH3-like domain superfamily	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR008145 all species →	Domain	Guanylate kinase/L-type calcium channel beta subunit	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46360 all species →	DISKS LARGE HOMOLOG 5	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0042981 all species →	Biological Process	regulation of apoptotic process	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0035331 all species →	Biological Process	negative regulation of hippo signaling	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K24050	DLG5; discs large protein 5	-	Hippo signaling pathway - fly	ko04391	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.