Gene detail

Detailed information of XP_044183609.1 in Acropora millepora

Genomic Location: NC_058076.1:11918115...11934150
NR annotation: XP_044183609.1, peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase-like [Acropora millepora]
Species Acropora millepora · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_044183609.1

ATGGCCTCCCCTACTCACGGAAATGCGATTGTTGTCGAAGAGGATGGCAAGTTTCAACAGTACATCGATGTGGCTGGAAACAGACTGGTTGTGGTGGATTTTTCCGCTCCTTGGTGTGGCCCATGCCGTATGATGGCCCCCATTTTTGCGCAGTTGAGTATCAAGTATTCAGCGGCAATTTTTTTGACAGTTGACACGGACCAGTGTAAGACAACTGCAAAAGTCAATGGTATCAGAGTTATGCCAACATTCTTCTTTTACAAGAACAGAAGGAAGGTTGATGAAATGCAAGGAGCAGATGCCAGAGGGCTGGAAGATAGAATCAACCAGTGGATTGGGGGTGCTGTGGACACTGTAGTTGTTGATTCCAAACGAGTGGCAATAGGGCGGAACTGGGATTGTTTTGAACAGCTACTAGACAATCCTCCAGAAGTGTTCATGGATGCTTCACAGCTGCTTCTCAAGTTTGCATCCAACATTATCAACAGCCCTGACAATCCAAAGTTCCGCACCATACGAGTGGGCAACAAGATCTTCCAATCGCGTCTTCTTCCTGTTAATGGCGCTGTGGAATGTCTTTTTACCATGGGATTCCAAGAGCGAGGTGATCAGCTTGTTTGCCCACAAGGTGAATCATTGGAGAAAATGCTGATTCTCCACGATACGTTGAATGATGAGAGAAGCCATCGCAGTGTTAGCCAGGAGCCGCCGTCAAGAACACAAGGATTCCACCCCTTAGGCTGCCCAGCAGAAATCATGACAGGGTGTGAGCAACCTTCTATCCTTCCAAGTTCACCAACCGCCCCAACGGATCAGAGACAGGAAAGAGATTTTCTACTCAGACTTCAAAGCTTTTTACAGCATGTCCTTCTTTACGAAGATGAAAATTTGCAAAGACAAACGCGAAACATCATTCCCTTGGCGGAATTAATGGAAAAAGCCAAAGAGTCCAGCGAAAAAACCAAGCAAGCTGGAGATTCTGGTGTCGATGAACGAGATTGTCTTATTTTAGTGCTTCTTGACTGGTTCAAGGGTTCGTTTTTCCAGTGGGTGGACAAGCCCCTCTGTGCGTACTGTGGCTCTATGACATTTGCCATTGGGGTTGTTCAACCGACACCTGAAGAAGCTTTCTGGGGAGCTGGGAATGTGGAAAGCTACAAATGTCAGAATTGTGGCAAGAAAACAAGATTCCCTCGCTACAATCACCCGGCAAAACTCTTAGAAACTCGTCAGGGGAGGTGTGGTGAGTGGGCCAACTGCTTCACGCTGATTTGCCGCGCTATGGGATTCGAGTCGCGTCACGTGCTTGACTGGACAGATCACGTGTGGACGGAAATTTACTCCGAGGCACAGCAGAGATGGCTGCACTGTGATGCGTGCGAAAACAGCTGTGATAAGCCACTTATTTACGAGGCTGGCTGGGGAAAGAAGCTCTCTTACATCATTGCATTCTCTCATGAACAAGTGTTAGATGTGACTTGGCGCTACTCCGCCAAACACGACGAGGTTCGCAAGGCGAGAACGTTAGTCACGGAGGAGTGGCTGGAAAAGACCCTTGCGAAATTGACAGAAGAGCGTCAAAGGAACTTAACTGAAGACAGAAGGAAAGTTTTGATGGATCGCCAGGTGAAGGAACTGGTGGAGTTTTTTACCATAAAAACAGTTCGTGATGGCGAGCTCCAAGGACGAGTGTCTGGTGACTTGGCGTGGAGACTGTTACGAGGAGAAACGAGGCCAGAAATAGAAGAATACAATCACGCACCTTATATTTATAAACCCACAGAGATGGAAATCAGGGAAAAGAGACTACGGTTTTGCTTCAACTGCGTGATAAACAAGTATCTGAGAGGTTTTGAAAGAAAACTTGACATCTCAGACTGGCAGTCCAGAGCCGCTGGCTTCAATGCAATAACGCGGAAAGTGGAGACGGATTGGAAAATGACTTACTTGTCGAGAACAGAATCCTCTCCAACGGGTTCCATCTCGTGGCAAGTTGATTTAAGCTCCTGTGATCTAGAGATTGATAGCGTTACTGTGGTAGCGACAAGCGACACGTTTCATTCTGGACAAGTAGAATGGAAACTAAGCGGAGACGAGGAGAGTCAAAGCGAGATACTTTCTGGAGGACGAGAATCGACCATTACGTCAGTTCTCAGTGGCTCTAAGACTCTCAAACTCACAGCCACCCTGAGTGGCGGGAAAGGAAACGTCGCCTGGCAACACGCACAGCTATTTCGTCAACCACTCGACAGCCAGAGCGACTACCCACTCGATGTTGCGATCTTCCTCCGAGAACCGACTCGGGACACCCAACTCTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9JI78	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Mus musculus OX=10090 GN=Ngly1 PE=1 SV=2
Q96IV0	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Homo sapiens OX=9606 GN=NGLY1 PE=1 SV=1
Q4R6F3	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Macaca fascicularis OX=9541 GN=NGLY1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002148 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00085 all species →	Thioredoxin	Thioredoxin	Domain	Interproscan
PF09409 all species →	PUB	PUB domain	Domain	Interproscan
PF01841 all species →	Transglut_core	Transglutaminase-like superfamily	Family	Interproscan
PF04721 all species →	PAW	PNGase C-terminal domain, mannose-binding module PAW	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR008979 all species →	Homologous_superfamily	Galactose-binding-like domain superfamily	Interproscan
IPR013766 all species →	Domain	Thioredoxin domain	Interproscan
IPR038765 all species →	Homologous_superfamily	Papain-like cysteine peptidase superfamily	Interproscan
IPR017937 all species →	Conserved_site	Thioredoxin, conserved site	Interproscan
IPR050883 all species →	Family	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	Interproscan
IPR002931 all species →	Domain	Transglutaminase-like	Interproscan
IPR018997 all species →	Domain	PUB domain	Interproscan
IPR036249 all species →	Homologous_superfamily	Thioredoxin-like superfamily	Interproscan
IPR036339 all species →	Homologous_superfamily	PUB-like domain superfamily	Interproscan
IPR006588 all species →	Domain	Peptide N glycanase, PAW domain	Interproscan
IPR038680 all species →	Homologous_superfamily	PAW domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12143 all species →	PEPTIDE N-GLYCANASE PNGASE -RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000224 all species →	Molecular Function	peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0006515 all species →	Biological Process	protein quality control for misfolded or incompletely synthesized proteins	Interproscan
GO:0006516 all species →	Biological Process	glycoprotein catabolic process	Interproscan
GO:0006517 all species →	Biological Process	protein deglycosylation	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01456	E3.5.1.52, NGLY1, PNG1; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase	EC:3.5.1.52	Protein processing in endoplasmic reticulum	ko04141	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.