Gene detail

Detailed information of XP_044184082.1 in Acropora millepora

Genomic Location: NC_058077.1:4962495...4991952
NR annotation: XP_044184082.1, histone-lysine N-methyltransferase SETDB1-like isoform X2 [Acropora millepora]
Species Acropora millepora · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_044184082.1

ATGACTGACAAAACACTTCAGAAGAAAACCAAATACAAAGTCAAGTTTGACAAAGGATCGAGAGGGCTTTTGTCGTCCAATCATATTGCTTTGGAAAGCTACCCACACCCATCAGTGTTGAATGTGGGAAGCCGTGTTGTAGCACTAAGACCTAGGGACACAGCCGAAGAAAATGCTTCTTGGCGGAAACCTTCTACAGGGATTTATGGCAAACTAGATGTGTTATATGCTGGAATAGTAGCTGAGAATGCTTGTACTGAAAACAAGAACAGATTTCTCGTTTTCTTTGATGATGGTTTTGCACAGTATCTGCCTGTCAAGAAGCTCCACCATGTTTTCCACACAGGAACAAAGGCTTGGGATGAAGTAGCTGAACATTCCAGAGAGTTTATTCAAGAATATCTTGAAGAATTTCCCAATCGCCCAATGGTGAAGCTTAAAGCCGGCCAGTGGGTGAAAACAGAGTGGAGAGGCCAGTGGTTGAAAGCAAGAGTTGTGCAGCTGGACTGCAGTTTAGTTAAGATGTTGTTTCAGATAGATAACCGCTCAGAATGGCTTTACAGAGGATCAACTAGATTGGGACCTTTATTTAGTGCCTTGGTTGATGGCAAGATTTCCACAGCCAGGAAGAAGAGGTCACGTAAACTGACAAGAGGGAAGACTACCGAGCCTTTCATTGACTACAGTATCACAAAGCCATGTCTGGGAATTTCACCTTACAGCAAAACAGATCCCAATGGCGAAGAGCAGCGAAAGCTGGAAGAAAAGCGACAGCAAACACAACTTGAGCAGCAGCGACAACACGAGCATCAAGAACAGATCAGAGACGAGAATAACAAGATGTCAGCCTCAACGGTTCCTGCCAAAACTACAAATACGAGTAGTAATCAGGCAAATGTGGCCAGCACTTTGAGTGCCCCCACGACATCTTCAACAATGACATCAGCTACTGAAAATGTCAAAACATCCTCAACAGTTACAACTGAATTGTCTGCACCAAGGTCACAGGTCACTGGGCCTACTGATAATGCAAACGCAGGACCAACAACAGGCGGTGTAAAAGAGACTCCGGGTTCAGTGGAGTCAAGTAATTCAGTAACGCTGAACGATTCTCAGTCTAAGAGCAGCTGTGAAGGCAGTAGCCATGCAACTCCTCCATCATCACTGGGCCAACAAAGTACTGCAACTATTAGCAAATGCGGGAATGTTTCATGCATTGGGTGTTGCAACTGCGGTAACAGCTCTTTGTCAGCTATCCAAGCCAGCCATGCAAGGAAGAAAACCAACGCAGGTTTAGTCATCACAAAGGACCGTTTGCAAAGATCCAGTGGGGTTGAAGTTATTGACTTGGAGGGCGACGCCACAGCCGGGCTGGTCAGTGTTTCCATGGAAACAGACCATATACTAGATTCATTGACGTCGCAAAAAACTGAGTCATGGGAAGCTCCTTGGCTTCGAGCCAATCGACGAGATGCTAGAAGCACTGGCAGAGCTCGCGTCCCTGCTTTCCAAATCCCAGTAAACAGCAAACAAAAGCAGGACGCCGCTTCTTTGATCCAAGAAAGGCTGAAACAAAGAGAAAAGAAGAAGCCCGGAGTGAGTGAAGCACCTGGGTACCCTGCGCTTTCCTCCAAGCCTGCGATAAAAGGACCCCATAGATGTAGCAAGCTTTGTAATTCAACCCTGAGTATTTCAGATCTGGAAAGGGTGAAACACAATCCGAGAGCAATCCCTCTCTTGCTCAAATGGAAAAGAGAAATAGCGCAACGTCATCCTGGCAATAAGAAAACTGTGTACTATCGAACGCCATGCAACAAAAGACTGAGATCATTTGCAGAGCTTGCAAATTATTTGGCAATAACCGAAGCTGCCAATGTAACGATAGATCAATTCAGTTTTGACCCGGATGTATCTTGTAAAGACACGGTGTACAGAGATGTGGTGCCCATTTGTCCTGACATTTCCCGCAGCGAAGAAAAAATCCAAATCTCGGTTGTTAATGAAGTGGACACGTGCTTTCCGCCACCAATTGATTACGTCTCAAAGAGGATTCTCGCTGAAGGAGTCAACGTGGTTCTTGATCCAGGTTTCTTGGCATGCTGTGACTGTACAGACAATTGTCAGGATAAGTCCAAATGCTCATGCTCGCAACTGACAATCCAAGCGTCTGCTTCCGTGGGAGGCAAAGAGGATTCAACCACTGGTTATGAATTCCGCATGCTCAGGGAATGTGTCCAGACAGGCATTTACGAATGCAATGGGAACTGTGCATGCGGGCCCCAGTGCTTTAATCGTGTTGTTCAGAACGGCATTCAACTTCGATTACAAGTGTTTAAGACGGAAAACAGGGGCTGGGGTTTGCGGTGCCTGGATGACATTCCTATGGGAACGTTTGTTTGTACCTATGCGGGGCAAATTCTCAACGAAGACATGGCCAACAAGGAAGGAAGAGATTTTGGAGATGAGTACTTGGCGGAATTGGATCATATCGAGGTTGTGGAAAAAGCGAAAGAAGGCTACGAGTCTAACGTATCAGATTTAGAAGAAGATGACAATGTCATTTACCAAACTTTGGGCGGAGATACTTCCTCTTCCGCCAGTCCTTCTGAAAACAGTGGCGAAAGTTCGCTGTCTGAAGAAGAGTCATCGGAGGCTGACTCGGTGCTAAGTGAAGACAGTTTCAGTTCAGGAAAAAGGCCAAAACAAGAAGACTGCATGAACACCAACCAGAAGCCACAAAGACGCAAGAAAAGAAAGAGATCATCGAAGAAATGTGAGAAGAAAGCAAGGGTTGTGCAGGGAGAGGAAGGTGAACGTGAATCAAAAGCAGAAGTTTTATCATCGAACCCCGCCGATGAAAAATGGTGTTACATAGCTTTGAAACGTAACCATGACAACCAGAAAGAGGCGGCCGCGTTTTTGAAGAAAATGATGAAAGGCGAGGTTACCTCAAAGAGTGGAGTCCAGGCTATCGTAGATCTAGCCGTTGTGAAGACGGAAGGAAAAAATGAAAAACAAAAAGAAGCAGAAAAATTCAAGCAAGAGATGGATGGAGAGGAGAAGAACGTTAGCCAGAGCAGTGACTTCGATTTTGACGAAGTAGAGGAGTCGTTTTTGCGGAAAATGCGAGTAAATGCTCTGCAGAGTGAATCAGGGAATGATGCTACGAATTCAGCTCATGAAACTAAGGACATTAAAAAACCCTGCAAACAGCGCACGGATCACAGCATCGAGGAACACTACGTGAACATCATTGATTTGACAAGCGAACCTGAGGCTGACACCGGCAAACAAAACGTACCTTTAGAAACTATTGAAGTACAGCCGAAATCAAATGTGAAGGAAACACCACTGACCAAACTAGATGCTACGTCTACTCTGTTGTTGCGAGAACCTTGTCAACCGGATAAAATCCAGAAAAAGCCTGGTAATCAGGAAGCAAATGCAAACTCTGAGACTGTCCCCGCTCCTTCACTTATTTCTGTCGAGGATCTTTCAAAACTCGCGGCGAAAAATCCCACAGTATCGGACGAGCCGCCAGTTCTAACAAAAATGAATCCTTCTCCACGGAATTCTCTTGAAGAAATGATTTCTCGGTTAAAGACGCGTGTATTTACTACACAAAAGTCTTCGTCAGCTGCCAGTTTAAACGAAACTGAAGGACCAGCTGATATGGGCTTTGAAACACCAATTGCCGACGCAGTAGACAATTGCTCGATTGATAAATCCTCAGGAAAGGTAGACAATTCATTGAAGTTTTCGGGGGAGCCAATATCCGATCCATCTTCGCCCGATACAGAAAACATCGAGTCATGTCCGCCCTCTCCATCGAGTTTGCACTCCGATGTGTCGAAGACCGAGTCTCTGGACCGGAAGTCAGAGGTGTCAACCGGAAGCTCGAGACGCAGCACTGGAGTGTCGTCAAAGCCACCCGCCAAAAGATTAAAAACAAACAAGCCCAAGATTCACTACTCTCGCTCTCATCCCAAACCCTCCACAACCAACCCTTCAATGAAAGCCTCACCCAACACACCATCGCCCTCACGCCCCTCTCTGTCGCGCCAGTCCTCGGCCAGTAGCAAGAAAATGAGCACTAGGTTGATGTTTGGAGAAGAGCACTGCTATGTCATCGACGCTAAGGCATATGGGAACTGTGGTCGATATTTGAATCATAGCTGTACCCCAAACTTGTTTGTCCAGAATGTGTTCGTAGACACTCATGACCTTCGTTTTCCCTGGGTTGCCTTCTTCACTCAACAGAATGTGCCTGCCGGAACCGAATTGACGTGGGACTATGCTTATGAGGTGGGAAGCGTCAAAGGCAAAGTACTGCACTGCTATTGCGGGTCAGCGGAGTGCCGTGGAAGGCTGCTGTGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O88974	Histone-lysine N-methyltransferase SETDB1 OS=Mus musculus OX=10090 GN=Setdb1 PE=1 SV=1
Q15047	Histone-lysine N-methyltransferase SETDB1 OS=Homo sapiens OX=9606 GN=SETDB1 PE=1 SV=1
Q6INA9	Histone-lysine N-methyltransferase SETDB1 OS=Xenopus laevis OX=8355 GN=setdb1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002134 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00856 all species →	SET	SET domain	Family	Interproscan
PF18358 all species →	Tudor_4	Histone methyltransferase Tudor domain	Domain	Interproscan
PF01429 all species →	MBD	Methyl-CpG binding domain	Domain	Interproscan
PF05033 all species →	Pre-SET	Pre-SET motif	Family	Interproscan
PF18359 all species →	Tudor_5	Histone methyltransferase Tudor domain 1	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR046341 all species →	Homologous_superfamily	SET domain superfamily	Interproscan
IPR051516 all species →	Family	Histone-lysine N-methyltransferase SETDB	Interproscan
IPR007728 all species →	Domain	Pre-SET domain	Interproscan
IPR001214 all species →	Domain	SET domain	Interproscan
IPR041292 all species →	Domain	Histone methyltransferase, Tudor domain 2	Interproscan
IPR001739 all species →	Domain	Methyl-CpG DNA binding	Interproscan
IPR041291 all species →	Domain	Histone methyltransferase, Tudor domain 1	Interproscan
IPR003616 all species →	Domain	Post-SET domain	Interproscan
IPR016177 all species →	Homologous_superfamily	DNA-binding domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46024 all species →	HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0010629 all species →	Biological Process	negative regulation of gene expression	Interproscan
GO:0046974 all species →	Molecular Function	histone H3K9 methyltransferase activity	Interproscan
GO:0051567 all species →	Biological Process	obsolete histone H3-K9 methylation	Interproscan
GO:0070828 all species →	Biological Process	heterochromatin organization	Interproscan
GO:0090309 all species →	Biological Process	obsolete positive regulation of DNA methylation-dependent heterochromatin formation	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0042054 all species →	Molecular Function	histone methyltransferase activity	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11421	SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase	EC:2.1.1.366	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.