Gene detail

Detailed information of XP_065646240.1 in Hydra vulgaris

Genomic Location: NC_088921.1:13592277...13619545
NR annotation: XP_012559069.2, glutamate--cysteine ligase regulatory subunit [Hydra vulgaris]
Species abbreviation HVULG · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P48507	Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1
O09172	Glutamate--cysteine ligase regulatory subunit OS=Mus musculus OX=10090 GN=Gclm PE=1 SV=1
P48508	Glutamate--cysteine ligase regulatory subunit OS=Rattus norvegicus OX=10116 GN=Gclm PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005404 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00248 all species →	Aldo_ket_red	Aldo/keto reductase family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036812 all species →	Homologous_superfamily	NADP-dependent oxidoreductase domain superfamily	Interproscan
IPR023210 all species →	Domain	NADP-dependent oxidoreductase domain	Interproscan
IPR032963 all species →	Family	Glutamate--cysteine ligase regulatory subunit	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13295 all species →	GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006750 all species →	Biological Process	glutathione biosynthetic process	Interproscan
GO:0017109 all species →	Cellular Component	glutamate-cysteine ligase complex	Interproscan
GO:0030234 all species →	Molecular Function	enzyme regulator activity	Interproscan
GO:0035226 all species →	Molecular Function	glutamate-cysteine ligase catalytic subunit binding	Interproscan
GO:0035229 all species →	Biological Process	positive regulation of glutamate-cysteine ligase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11205	GCLM; glutamate--cysteine ligase regulatory subunit	-	Ferroptosis	ko04216	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.