Detailed information of XP_065666797.1 in Hydra vulgaris

Genomic Location: NC_088930.1:30303927...30347616
NR annotation: XP_047136656.1, GTP-binding protein 4 [Hydra vulgaris]
Species Hydra vulgaris · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q99ME9GTP-binding protein 4 OS=Mus musculus OX=10090 GN=Gtpbp4 PE=1 SV=3
Q9BZE4GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3
Q9V411Nucleolar GTP-binding protein 1 OS=Drosophila melanogaster OX=7227 GN=Non1 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004362 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF17835
all species →
NOG1_NNOG1 N-terminal helical domainDomainInterproscan
PF08155
all species →
NOGCTNOGCT (NUC087) domainDomainInterproscan
PF06858
all species →
NOG1Nucleolar GTP-binding protein 1 (NOG1)FamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR041623
all species →
DomainNOG1, N-terminal helical domainInterproscan
IPR012973
all species →
DomainNOG, C-terminalInterproscan
IPR027417
all species →
Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan
IPR010674
all species →
DomainNucleolar GTP-binding protein 1, Rossman-fold domainInterproscan
IPR024926
all species →
FamilyNucleolar GTP-binding protein 1Interproscan
IPR006073
all species →
DomainGTP binding domainInterproscan
IPR005225
all species →
DomainSmall GTP-binding protein domainInterproscan
IPR031167
all species →
DomainOBG-type guanine nucleotide-binding (G) domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR45759
all species →
NUCLEOLAR GTP-BINDING PROTEIN 1Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005525
all species →
Molecular FunctionGTP bindingInterproscan
GO:0003723
all species →
Molecular FunctionRNA bindingInterproscan
GO:0003924
all species →
Molecular FunctionGTPase activityInterproscan
GO:0005730
all species →
Cellular ComponentnucleolusInterproscan
GO:0042273
all species →
Biological Processribosomal large subunit biogenesisInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K06943NOG1; nucleolar GTP-binding protein-Ribosome biogenesisko03009deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_065666797.1 across 60 RNA-seq samples of Hydra vulgaris. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

60Samples
60TPM > 0
8Conditions
263.0Max TPM
219.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Regenerating head · dmso treatment 18 18 208.32 258.87
Regenerating head · 25uM U0126 treatment 15 15 211.54 263.03
Regenerating foot · dmso treatment 9 9 223.65 252.95
Regenerating foot · 25uM U0126 treatment 8 8 234.62 254.34
Regenerating head · u0126 treatment 3 3 205.96 224.61
Whole animal · 25uM U0126 treatment 3 3 251.80 261.55
Whole animal · dmso treatment 3 3 247.33 261.26
Regenerating foot · u0126 treatment 1 1 239.51 239.51

Per sample · hover a bar for the full sample record

Show the sample table (60 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR36435285 Regenerating head · dmso treatment Regenerating head 0hpa dmso treatment SRP654941 258.87
SRR36435309 Regenerating head · dmso treatment Regenerating head 3hpa dmso treatment SRP654941 248.78
SRR36435308 Regenerating head · dmso treatment Regenerating head 3hpa dmso treatment SRP654941 241.30
SRR36435272 Regenerating head · dmso treatment Regenerating head 12hpa dmso treatment SRP654941 240.98
SRR36435284 Regenerating head · dmso treatment Regenerating head 0hpa dmso treatment SRP654941 236.59
SRR36435286 Regenerating head · dmso treatment Regenerating head 0hpa dmso treatment SRP654941 229.22
SRR36435304 Regenerating head · dmso treatment Regenerating head 1.5hpa dmso treatment SRP654941 228.85
SRR36435306 Regenerating head · dmso treatment Regenerating head 1.5hpa dmso treatment SRP654941 218.29
SRR36435307 Regenerating head · dmso treatment Regenerating head 3hpa dmso treatment SRP654941 216.38
SRR36435273 Regenerating head · dmso treatment Regenerating head 12hpa dmso treatment SRP654941 210.02
SRR36435313 Regenerating head · dmso treatment Regenerating head 0hpa dmso treatment SRP654941 206.09
SRR36435305 Regenerating head · dmso treatment Regenerating head 1.5hpa dmso treatment SRP654941 199.96
SRR36435279 Regenerating head · dmso treatment Regenerating head 8hpa dmso treatment SRP654941 197.74
SRR36435310 Regenerating head · dmso treatment Regenerating head 0hpa dmso treatment SRP654941 195.68
SRR36435277 Regenerating head · dmso treatment Regenerating head 8hpa dmso treatment SRP654941 190.89
SRR36435280 Regenerating head · dmso treatment Regenerating head 8hpa dmso treatment SRP654941 171.39
SRR36435312 Regenerating head · dmso treatment Regenerating head 0hpa dmso treatment SRP654941 135.25
SRR36435271 Regenerating head · dmso treatment Regenerating head 12hpa dmso treatment SRP654941 123.52
SRR36435281 Regenerating head · 25uM U0126 treatment Regenerating head 0hpa 25uM U0126 treatment SRP654941 263.03
SRR36435299 Regenerating head · 25uM U0126 treatment Regenerating head 3hpa 25uM U0126 treatment SRP654941 239.17
SRR36435275 Regenerating head · 25uM U0126 treatment Regenerating head 8hpa 25uM U0126 treatment SRP654941 236.18
SRR36435296 Regenerating head · 25uM U0126 treatment Regenerating head 1.5hpa 25uM U0126 treatment SRP654941 232.87
SRR36435303 Regenerating head · 25uM U0126 treatment Regenerating head 0hpa 25uM U0126 treatment SRP654941 232.26
SRR36435302 Regenerating head · 25uM U0126 treatment Regenerating head 0hpa 25uM U0126 treatment SRP654941 229.59
SRR36435295 Regenerating head · 25uM U0126 treatment Regenerating head 1.5hpa 25uM U0126 treatment SRP654941 224.57
SRR36435294 Regenerating head · 25uM U0126 treatment Regenerating head 1.5hpa 25uM U0126 treatment SRP654941 214.21
SRR36435298 Regenerating head · 25uM U0126 treatment Regenerating head 3hpa 25uM U0126 treatment SRP654941 213.66
SRR36435301 Regenerating head · 25uM U0126 treatment Regenerating head 0hpa 25uM U0126 treatment SRP654941 202.79
SRR36435282 Regenerating head · 25uM U0126 treatment Regenerating head 0hpa 25uM U0126 treatment SRP654941 199.39
SRR36435276 Regenerating head · 25uM U0126 treatment Regenerating head 8hpa 25uM U0126 treatment SRP654941 197.14
SRR36435283 Regenerating head · 25uM U0126 treatment Regenerating head 0hpa 25uM U0126 treatment SRP654941 177.98
SRR36435297 Regenerating head · 25uM U0126 treatment Regenerating head 3hpa 25uM U0126 treatment SRP654941 165.34
SRR36435274 Regenerating head · 25uM U0126 treatment Regenerating head 8hpa 25uM U0126 treatment SRP654941 144.89
SRR36435300 Regenerating foot · dmso treatment Regenerating foot 3hpa dmso treatment SRP654941 252.95
SRR36435266 Regenerating foot · dmso treatment Regenerating foot 1.5hpa dmso treatment SRP654941 244.17
SRR36435267 Regenerating foot · dmso treatment Regenerating foot 1.5hpa dmso treatment SRP654941 236.90
SRR36435278 Regenerating foot · dmso treatment Regenerating foot 3hpa dmso treatment SRP654941 233.45
SRR36435265 Regenerating foot · dmso treatment Regenerating foot 1.5hpa dmso treatment SRP654941 221.96
SRR36435289 Regenerating foot · dmso treatment Regenerating foot 3hpa dmso treatment SRP654941 219.91
SRR36435322 Regenerating foot · dmso treatment Regenerating foot 0hpa dmso treatment SRP654941 208.15
SRR36435311 Regenerating foot · dmso treatment Regenerating foot 0hpa dmso treatment SRP654941 205.18
SRR36435323 Regenerating foot · dmso treatment Regenerating foot 0hpa dmso treatment SRP654941 190.18
SRR36435320 Regenerating foot · 25uM U0126 treatment Regenerating foot 0hpa 25uM U0126 treatment SRP654941 254.34
SRR36435319 Regenerating foot · 25uM U0126 treatment Regenerating foot 3hpa 25uM U0126 treatment SRP654941 246.47
SRR36435316 Regenerating foot · 25uM U0126 treatment Regenerating foot 1.5hpa 25uM U0126 treatment SRP654941 240.76
SRR36435315 Regenerating foot · 25uM U0126 treatment Regenerating foot 1.5hpa 25uM U0126 treatment SRP654941 237.58
SRR36435318 Regenerating foot · 25uM U0126 treatment Regenerating foot 3hpa 25uM U0126 treatment SRP654941 235.50
SRR36435317 Regenerating foot · 25uM U0126 treatment Regenerating foot 3hpa 25uM U0126 treatment SRP654941 235.09
SRR36435314 Regenerating foot · 25uM U0126 treatment Regenerating foot 1.5hpa 25uM U0126 treatment SRP654941 221.62
SRR36435321 Regenerating foot · 25uM U0126 treatment Regenerating foot 0hpa 25uM U0126 treatment SRP654941 205.60
SRR36435270 Regenerating head · u0126 treatment Regenerating head 12hpa u0126 treatment SRP654941 224.61
SRR36435269 Regenerating head · u0126 treatment Regenerating head 12hpa u0126 treatment SRP654941 219.38
SRR36435268 Regenerating head · u0126 treatment Regenerating head 12hpa u0126 treatment SRP654941 173.88
SRR36435290 Whole animal · 25uM U0126 treatment Whole animal 12h 25uM U0126 treatment SRP654941 261.55
SRR36435288 Whole animal · 25uM U0126 treatment Whole animal 12h 25uM U0126 treatment SRP654941 248.60
SRR36435287 Whole animal · 25uM U0126 treatment Whole animal 12h 25uM U0126 treatment SRP654941 245.24
SRR36435291 Whole animal · dmso treatment Whole animal 12h dmso treatment SRP654941 261.26
SRR36435293 Whole animal · dmso treatment Whole animal 12h dmso treatment SRP654941 257.02
SRR36435292 Whole animal · dmso treatment Whole animal 12h dmso treatment SRP654941 223.71
SRR36435264 Regenerating foot · u0126 treatment Regenerating foot 0hpa u0126 treatment SRP654941 239.51

Source: CnidoSite RNA-seq expression matrices (HVULG_TPM, StringTie quantification over 60 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Hydra vulgaris tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated18XP_065675249.10.946478243948074
Negatively correlated20XP_065667357.1-0.765719377880581

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Hydra vulgaris, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

DatasetTissue / stageCellsCell typesThis geneMarker of
HVULG_siebert_atlasWhole animals · Adult (whole animal)25,43842not in this dataset

A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

Peak calls overlapping this gene

AssaySamplePeaksRegion
ChIP-seqH3K27ac_head1Intron 1
H3K27ac_regenerating_head_4hr3Intron 2 · Promoter (<=1kb) 1
H3K27ac_regenerating_head_6hr1Promoter (<=1kb) 1
H3K4me2_regenerating_head_0hr1Promoter (<=1kb) 1
H3K4me3_head1Promoter (<=1kb) 1
H3K4me3_regenerating_head_0hr1Promoter (<=1kb) 1
H3K4me3_regenerating_head_24hr2Intron 1 · Promoter (<=1kb) 1
H3K4me3_whole_polyp_24hr_DMSO_control3Promoter (<=1kb) 2 · Promoter (1-2kb) 1
H3K4me3_wholeAnimal1Intron 1
H4K20me1_regenerating_tips_24hrs1Intron 1
H4K20me1_regenerating_tips_8hrs3Intron 2 · Promoter (2-3kb) 1
H4K20me1_whole_polyp_ALP_treated5Intron 4 · Promoter (2-3kb) 1

Browse the full epigenomic landscape of this species: ChIP-seq.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
TOP