Gene detail

Detailed information of XP_065670581.1 in Hydra vulgaris

Genomic Location: NC_088931.1:76905856...77014666
NR annotation: XP_047142948.1, LOW QUALITY PROTEIN: rho-associated protein kinase 2 [Hydra vulgaris]
Species Hydra vulgaris · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

LOC100212937

ATGACTGAAGTTGAAAAACGTTACCAAACTTTAGCTGAAAAACTACTAAAGCCAACTAATGAGCTCTACGTTGAGGGACTACTAGATACTGTGACATCATTGTACTATGAGTGCACATCATCTCATATCCGGAATGAGAAAAACTTTGAAAACTTTATGAAGCGATATGCTGCTGCTGCAGAAGAAATTACAAAATCTCGCATTAATATAAAAGATTTTCATGAGATAAAAGTTTTAGGTCAAGGTGCATTTGGTGAAGTTAAGCTGATGCGTCATAAAGATACCAAACAGCTATATGCAATGAAACTTCTCAGTAAATTTGAAATGATTAAAAAGTCTGAAGTTGCTTTTTTTTGGGAAGAGCGAGACATTATGGCACATGCAAATTCTGAATGGATTATGGCGATTCATTATGCTTTTCAAGATGATAAATATTTATACATGGCTATGGATTATATGCCAGGTGGTGATTTTGTTAGTCTCTTGTCTAATTATGATATTCCTGAAGATTGGGCTGCATTTTACATAGCAGAGTTAGTGTTAGCTATCGATGCTCTTCATAAGTATGGCTACGTTCACAGAGACATAAAACCAGACAACATGTTGTTAGATAAAAATGGCCATTTAAAGTTAGCAGATTTTGGTACCTGTATACGGATGGATAAAGATGGTTTAGTACACTCTGACACTGCTGTTGGCACTACTGATTACCTTTCACCTGAGGTTTTACTTACTGAACGTCATGGTCATGGTGTTTATGGACGTGAATGTGATTACTGGGCTGTTGGTGTAGTTTTATATGAACTTCTTGTTGGTGATCCACCTTTTCTTGATCAATCGTATGCTGGTACATATGAAAAAATCTTGAATCATAAAAATTCTCTTCAATTTCCAACTGACATTGAAATAAAGAGTGATTGCAAAAAAGTTATATGTGGATTTTTAACAACAAGAGAACATCGACTTGGTAGAAATGGGATAGATGAAATTAAAAGTTATAAGTTTTTTCAAAGGGAAGATTGGAACTGGGATAATATACGAAGCAATGTTGCCAAATTCACACCTGATTTAGATAGTGATATTGACACCAGAAATTTTGATGATTTTTCTGATCTAGAAAAAAAAAACACTGATACATTTGAATTATCAAAGGTTTTTACAGGAAATCATTTGCCATTCATTGGTTATACTTATTCAAAACATAACAGATTAATTGGAGGAAATCAGGGAACATCTGAAGAGAACAATAATAAGGTCCAAAGTTTGTTAACTAAAATCCGAGAAGTTGAAGATCAACTAAAAAACGAGAAAAATGCTAAAGATGAATCAGAAAAAATTTTAAAAAATTTAAAAAATAAGACACAGAAATTAACCAGTGATTGGGAAGCGGAGGTGGAACTACGCAAAAATGGGGAAGCAAAAATACGGGATTTAGAAAGAGCAGCTGCACTATACAAACATGACATAAAAGAAATACAACGTAAATTAGATGTTGAAACAGACACTAAAAAAAAATTTGAAGCAAAGTTTCAAGAGTTGCAAGCAAAGTTAGATAGTGAATCATCTACTAAAGAAGACAGCAATAAATTACAAAAAAAATTGATTATAGCAGAAAGAGAAAACAATGACTTGAAAGAAAAGTTAAGACTAGAGACAGAGGGAAATATAAAATGGAAAAAAATTGAGAACGATTATCGAAAAGCCCAAGCTGTTGCAGATCATGCCTTTAAGGAACTTTTCGAAAAAAACAAACTTTTAGGAATTGCTAAGACTGATATAGAAAAAGAGTTAATGAAAGTGCAAGCTGCTCTGCAAGCTGAAACAGCTGCTCTTAAACAGGCAAATAATCAATGTCGAGACTTTGAAAAACAAAATGCTTTATTGAAAGATGAAGTTGATCAATTAAGAACAAAATATAAAAGTGATGCCAATGCCATGCAAAAATTACAAGATGAACTTATTGCTGTTGAAAAATCCAAAGCTAGTATTGCGTTTGAGCTTAAACAGTTAAAGGTTAAATATGAAATGGAGAAAACAAACTTTACTAATCGACAGCTAAAAGAGACAGATGTAAAAAAAAAGCTATCAGAAGTTCAAATATTGGAAAAAGAGATTGGTGATATACAAAAAGAGCGAGAAGAAAGAATTCGTATTGAATCAAAAGCCGCAAATCTTGAGCGTCTAATTAATGACTTACAATTAGATTTAAAAAATATTAAACAAAAAAATGTAAGGCTAGAAGAAGACTATCAAGCAAGTCAAAATAAAATTGATAGTTTGAATAGCTTGATGAAAGATGAAAATGCAAATCGTAATGATATTCAAAATAAACTTAATACAGTAATAAGTGAATTGACAGCACAGAAGACTAAAGAACAACAATTAAAATCTGATCTTGATCGAACTCTTGAAGAAAAGAAACAACTACAAGAAGCATACAACAAGTTAAAAAATGCTTCTGCAGCAGATAATATTCAAATAAAAGAATTGCAAAATCAACTAGAGGCTGAGCAATACTTTTCTAATCTTTATAAAACACAAGCGCGAGAGCTAAATGAGCAAGTTGATGAACAACGTAAACAGTCGCATGATCTTCTAAATGATCTTCATATGTCACAGGAAGACCGAGCTTCTCTTTCAGCTCAACTTGAATTAGCAATAGCAAAAGCTGAGTCAGAAGATTTAGCAAGATCAATTGCAGAGGAGCAAATCTGTGATCTTGAAAAAGAAAAGACAATGCTTGAACTTGAAATTAAAGATTTACTTGCCAAACATAAAGCTGATAGTTTTGAAAAGTTCAAAACGTTGCAAGAGGCTGATGAAAAAATTAGAGTCCTAGAAACTGAACTTCAAAATGAAGTTCGCAAAAGAATTGAAAGTATTGAACAGATAAAAACTGATATTGTGGAAAAAAAACAAAATGAGGAAATTGAGGCGTTGAAAAAAGCTGTCAAGCAAGAGCAAACTTTAAAGATACAAGCAGTTAACAAGCTAGCAGAAAAGATGTCAGAAAGAAAAGAAATTTCTTCAAAAGGAAAAGGCAACAAAGTAACTTCAGCAGAGTTGAAGAAAAAAGAAAAAGAAAACAAAAGACTTCAATTGTTACTAGAGCAGGAAAAAAATAAGTACCAAATTACATTTACCAAACATCAAGGTCAAAATAGTGAATTAAATAAAGAATTGGAGAAGCAGAAGGAAGTATTAACTAAAGTTATGATGGAATTAGAATCCAAAGGCATGGTTATTGAACAGTTACAAGAAGATAACAAGAATTTAAATACAGAAATAGAAAACTTGAGAGCTTTAGTTCCAGTAGGTACAAATAGCAGCATACTTCATCCAGCAAATATGAAGTTAGAAGGTTGGTTGTCTATTCCAGAAAGGAGAGTTAAAAAAAATATGTTATGGAAGAAACAATATGTTGTTGTGAGTCAGCAAAAAATATTTTTCTTTAACAATGAACAAGACAAAGCAACAAATACACCAGCTATGATATTAGACATTGGAAAACTTTTTCATGTTCGATCAGTGACACAAGGCGATGTAATTAGAGTTGATGTAAAAGACATACCCAAAATATTTCAGATTTTGTATGCCAATGAAGGTGAAAGTAAAAATCCTGAGGAAAAAACAGAACAAGACCAATTGGAGCAAGATAAAGCTGCTGTCGTCATTCCTTTTAAAGATCATCAGTTTGTTGTCATGCACTATCATATGCCGAATGCCTGTGATATGTGTCAAAGACAAATGTGGCATATGATTAAACCACCATTAGCTGTAGAATGTCGAAGGTGTCGTGTAAAATGTCATAAGGATCACGTAGATGAAGAAGAAGATGTGATACAACCATGCAAAGTAACTGTTGATCTTGCTACTGCAAAAGATTTACTAATACTTGCTAATGATGTTGATGAGCAAAAAAAATGGGTACAGGAACTATCTAAAAAAATTATTCGCAAAGGTGTTGGAGCCTTAAAAAAGAACAGTGATGCCACTACTAACATAATGCCTCGAAACCATTCTAAATCCTTCAATGGGAAAGAAAAAAACTTAAATCGATCAGTATCTGTTACATCTGGTTACACTCCAATGCTCTTAAAGAAAGAATAA

Transcript

rna-XM_065814509.1

ATCCGTTAAGTAAATAGAATTGACGgatgtccaaaaaaaaaaaaaaaaaaagcgaaacaattttttgtatggCAAATTATAGAAAATAGTGATTTGATCCtttgataaatgttttacaaagttgaattttattattttgcgcAAGAATTGTCATTAGCTTAGATTTTCaggcaaaaaatgaaaatagtttgCCTCTAATATTTGAACTAGAATAAAATGACTGAAGTTGAAAAACGTTACCAAACTTTAGCTGAAAAACTACTAAAGCCAACTAATGAGCTCTACGTTGAGGGACTACTAGATACTGTGACATCATTGTACTATGAGTGCACATCATCTCATATCCGGAATgagaaaaactttgaaaactttatgaaGCGATATGCTGCTGCTGCAGAAGAAATTACAAAATCTCGCattaatataaaagattttcatGAGATAAAAGTTTTAGGTCAAGGTGCATTTGGTGAAGTTAAGCTGatgcGTCATAAAGATACCAAACAGCTATATGCAATGAAACTTCTCAGTAAATTTGAAATgattaaaaagtctgaagttgcttttttttggGAAGAGCGAGACATTATGGCACATGCAAATTCTGAATGGATTATGGCGaTTCATTATGCTTTTcaagatgataaatatttatacatggCTATGGATTATATGCCAGgtgGTGATTTTGTTAGTCTCTTGTCTAATTATGATATTCCTGAAGATTGGGCTGCATTTTACATAGCAGAGTTAGTGTTAGCTATCGATGCTCTTCATAAGTATGGCTACGTTCACAGAGACATAAAACCAGACAACATGTTGTTAGATAAAAATGGCCATTTAAAGTTAGCAGATTTTGGTACCTGTATACGGATGGATAAAGATGGTTTAGTACACTCTGACACTGCTGTTGGCACTACTGATTACCTTTCACCTGAGGTTTTACTTACTGAACGTCATGGTCATGGTGTTTATGGACGTGAATGTGATTACTGGGCTGTTGGTGTAGTTTTATATGAACTTCTTGTTggtgATCCACCTTTTCTTGATCAATCGTATGCTGGTACATATGaaaaaatcttgAATCATAAAAATTCTCTTCAATTTCCAACTGACATTGAAATAAAGAGTGAttgcaaaaaagttatatgtGGATTTTTAAcaacaagagaacaTCGACTTGGTAGAAATGGGATAGatgaaattaaaagttataagttttttcaaagggAAGATTGGAACTGGGATAATATACGAAGCAatgttGCCAAATTCACACCTGATTTAGATAGTGATATTGACACCAgaaattttgatgatttttctgatctagaaaaaaaaaacactgataCATTTGAATTATCAaaggtttttaCAGGAAATCATTTGCCATTCATTGGTTATACTTATTCAAAACATAACAGatTAATTGGAGGAAATCAGggaaCATCTGAAGAGAACAATAATAAGGTCCAAAGTTTGTTAACTAAAATCCGAGAAGTTGAAGATCAACTAAAAAACGAGAAAAATGCTAAAGatgaatcagaaaaaattttaaaaaatttaaaaaataagacacaGAAATTAACCAGTGATTGGGAAGCGgaggTGGAACTACGCAAAAATGGGGAAGCAAAAATACGGGATTTAGAAAGAGCAGCTGCACTATACAAACATGACATAAAAGAAATACAACGTAAATTAGATGTTGAAACagacactaaaaaaaaatttgaagcaaaGTTTCAAGAGTTGCAAGCAAAGTTAGATAGTGAATCATCTACTAAAGAAGACagcaataaattacaaaaaaaattgattatagcAGAAAGAGAAaacAATGACTTGAAAGAAAAGTTAAGACTAGAGACAGAGGGaaatataaaatggaaaaaaattgagAACGATTATCGAAAAGCCCAAGCTGTTGCAGATCATGCCTTTAAGGAActtttcgaaaaaaacaaacttttaggAATTGCTAAGactGATATAGAAAAAGAGTTAATGAAAGTGCAAGCTGCTCTGCAAGCTGAAACAGCTGCTCTTAAACAGGCAAATAATCAATGTCGagactttgaaaaacaaaatgcttTATTGAAAGATGAAGTTGATCAATTaagaacaaaatataaaagtgaTGCCAATGCCATGCAAAAATTACAAGATGAACTTATTGCTGTTGAAAAATCCAAAGCTAGTATTGCGTTTGAGCTTAAACAGTTAAAGGTTAAATATGAAATGGAGAAAACAAACTTTactaatCGACAGCTAAAAGAGacagatgtaaaaaaaaagctatcagAAGTTCAAATATTGGAAAAAGAgattggtGATATACAAAAAGAGCGAGAAGAAAGAATTCGTATTGAATCAAAAGCCGCAAATCTTGAGCGTCTAATTAATGACTTacaattagatttaaaaaatattaaacaaaaaaatgtaaggCTAGAAGAAGACTATCAAGCAAGTCAAAATAAaATTGATAGTTTGAATAGCTTGATGAAAGATGAAAATGCAAATCGTAAtgatattcaaaataaacttaatacaGTAATAAGTGAATTGACAGCACAGAAGACTAAAGAACAACAATTAAAATCTGATCTTGATCGAACTCTTGAAGAAAAGAAACAACTACAAGAAGCATAcaacaagttaaaaaatgcTTCTGCAGcagataatattcaaataaaagaattgcaAAATCAACTAGAGGCTGAGCAATACTTTTCTAATCTTTATAAAACACAAGCGCGAGAGCTAAATGAGCAAGTTGATGAACAACGTAAACAGTCGCATGATCTTCTAAATGATCTTCATATGTCACAGGAAGACCGAGCTTCTCTTTCAGCTCAACTTGAATTAGCAATAGCAAAAGCTGAGTCAGAAGATTTAGCAAGATCAATTGCAGAGGAGCAAATCTGTGATcttgaaaaagaaaagacaaTGCTTGAACTTGAAATTAAAGATTTACTTGCCAAACATAAAGCTGATAGTTTTGAAAAGTTCAAAACGTTGCAAGAGgCTGATGAAAAAATTAGAGTCCTAGAAACTGAACTTCAAAATGAAGTTCGCAAAAGAATTGAAAGTATTGAACAGATAAAAACTgATATtgtggaaaaaaaacaaaatgaggAAATTGAGGCGTTGAAAAAAGCTGTCAAGCAAGAGCAAACTTTAAAGATACAAGCAGTTAACAAGCTAGCAGAAAAGATGTcagaaagaaaagaaatttcttCAAAAGGAAAAGGCAACAAAGTAACTTCAGCAGagttgaagaaaaaagaaaaagaaaacaaaagacttCAATTGTTACTAGAGCAGgaaaaaaataagTACCAAATTACATTTACCAAACATCAAGGTCAAAATAGTGAATTAAATAAAgaATTGGAGAAGCAGAAGGAAGTATTAACTAAAGTTATGATGGAATTAGAATCCAAAGGCATGGTTATTGAACAGTTACAAGAAGATAACAAGAATTTAAATACAGAAATAGAAAACTTGAGAGCTTTAGTTCCAGTAGGTACAAATAGCAGCATACTTCATccagcaAATATGAAGTTAGAAGGTTGGTTGTCTATTCCAGAAAggagagttaaaaaaaatatgttatggAAGAAACAATATGTTGTTGTGagtcagcaaaaaatatttttctttaacaatgAACAAGACAAAGCAACAAATACACCAGCTATGATATTAGACATTGGaaaactttttcatGTTCGATCAGTGACACAAGGCGATGTAATTAGAGTTGATGTAAAAGACATACCCAAAATATTTCAGattttgtatGCCAATGAAGGTGAAAGTAAAAATCCTGAGGAAAAAACAGAACAAGACCAATTGGAGcaagATAAAGCTGCTGTCGTCATTCCTTTTAAAGATCATCAGTTTGTTGTCATGCACTATCATATGCCGAATGCCTGTGATATGTGTCAAAGACAAATGTGGCATATGATTAAACCACCATTAGCTGTAGAATGTCGAAggTGTCGTGTAAAATGTCATAAGGATCACGTAGATGAAGAAGAAGATGTGATACAACCATgcaaagtaactGTTGATCTTGCTACTGCAAAAGATTTACTAATACTTGCTAATGATGTTGATGAGCAAAAAAAATGGGTACAGGaactatctaaaaaaattattcgcaAAGGTGTTGGAGccttaaaaaagaaCAGTGATGCCACTACTAACATAATGCCTCGAAACCATTCTAAATCCTTCAATgggaaagaaaaaaacttaaatcgaTCAGTATCTGTTACATCTGGTTACACTCCAATGCTCTtaaagaaagaataatTTTGCCTGAATAATTTGAATAACACCTGATTGTTACATTACCACCGAGTTGAATAGTTCGGACTCACTGAGTTGATTTATGCATCAACAACGAGTAATTCGGCAATCATGTGATAGCTAACTGGTCTACCTAAAATATAGAAGATATCAGAATTAAagaatgaatattttaaaaattcaaaggCTGCACTCTTTAATCTATTTGGTTCCTTGCCGTTTATATATCAATTCACCACAGACATAAAGCGTTTCACACAACAAAGGTCAATGAAAACTTgcaaattttgaacaaaaagttcCAAGATCGAGCTACTATTGTTGTAGTAgtctataaaaacaaaaatataaaaaacgaaTATAGAAATTTGATACTTTTTATGCCaatgtgttaaattttttttaaaaagaatcttcttttttattattattatta

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O75116	Rho-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=ROCK2 PE=1 SV=4
Q62868	Rho-associated protein kinase 2 OS=Rattus norvegicus OX=10116 GN=Rock2 PE=1 SV=2
O77819	Rho-associated protein kinase 1 OS=Oryctolagus cuniculus OX=9986 GN=ROCK1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002746 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08912 all species →	Rho_Binding	Rho Binding	Coiled-coil	Interproscan
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF00433 all species →	Pkinase_C	Protein kinase C terminal domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR015008 all species →	Domain	ROCK, Rho binding domain	Interproscan
IPR050839 all species →	Family	Rho-associated Serine/Threonine Kinase	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR000961 all species →	Domain	AGC-kinase, C-terminal	Interproscan
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR017892 all species →	Domain	Protein kinase, C-terminal	Interproscan
IPR046349 all species →	Homologous_superfamily	C1-like domain superfamily	Interproscan
IPR002219 all species →	Domain	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22988 all species →	MYOTONIC DYSTROPHY S/T KINASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0031267 all species →	Molecular Function	small GTPase binding	Interproscan
GO:0000281 all species →	Biological Process	mitotic cytokinesis	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005856 all species →	Cellular Component	cytoskeleton	Interproscan
GO:0007266 all species →	Biological Process	Rho protein signal transduction	Interproscan
GO:0018107 all species →	Biological Process	peptidyl-threonine phosphorylation	Interproscan
GO:0030866 all species →	Biological Process	cortical actin cytoskeleton organization	Interproscan
GO:0031032 all species →	Biological Process	actomyosin structure organization	Interproscan
GO:0048598 all species →	Biological Process	embryonic morphogenesis	Interproscan
GO:0072518 all species →	Molecular Function	Rho-dependent protein serine/threonine kinase activity	Interproscan
GO:1901888 all species →	Biological Process	regulation of cell junction assembly	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K17388	ROCK2; Rho-associated protein kinase 2	EC:2.7.11.1	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_065670581.1 across 60 RNA-seq samples of Hydra vulgaris. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

60Samples

60TPM > 0

8Conditions

19.5Max TPM

9.8Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Regenerating head · dmso treatment	18	18	7.94	14.83
Regenerating head · 25uM U0126 treatment	15	15	8.49	13.99
Regenerating foot · dmso treatment	9	9	10.83	14.03
Regenerating foot · 25uM U0126 treatment	8	8	11.06	13.65
Regenerating head · u0126 treatment	3	3	4.68	9.53
Whole animal · 25uM U0126 treatment	3	3	17.45	18.20
Whole animal · dmso treatment	3	3	17.65	19.47
Regenerating foot · u0126 treatment	1	1	10.93	10.93

Per sample · hover a bar for the full sample record

Show the sample table (60 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR36435309	Regenerating head · dmso treatment	Regenerating head	3hpa	dmso treatment	SRP654941	14.83
SRR36435272	Regenerating head · dmso treatment	Regenerating head	12hpa	dmso treatment	SRP654941	13.29
SRR36435285	Regenerating head · dmso treatment	Regenerating head	0hpa	dmso treatment	SRP654941	13.15
SRR36435307	Regenerating head · dmso treatment	Regenerating head	3hpa	dmso treatment	SRP654941	12.14
SRR36435284	Regenerating head · dmso treatment	Regenerating head	0hpa	dmso treatment	SRP654941	11.87
SRR36435306	Regenerating head · dmso treatment	Regenerating head	1.5hpa	dmso treatment	SRP654941	11.80
SRR36435308	Regenerating head · dmso treatment	Regenerating head	3hpa	dmso treatment	SRP654941	10.75
SRR36435304	Regenerating head · dmso treatment	Regenerating head	1.5hpa	dmso treatment	SRP654941	10.17
SRR36435286	Regenerating head · dmso treatment	Regenerating head	0hpa	dmso treatment	SRP654941	8.17
SRR36435305	Regenerating head · dmso treatment	Regenerating head	1.5hpa	dmso treatment	SRP654941	7.19
SRR36435277	Regenerating head · dmso treatment	Regenerating head	8hpa	dmso treatment	SRP654941	6.74
SRR36435310	Regenerating head · dmso treatment	Regenerating head	0hpa	dmso treatment	SRP654941	6.59
SRR36435273	Regenerating head · dmso treatment	Regenerating head	12hpa	dmso treatment	SRP654941	5.03
SRR36435279	Regenerating head · dmso treatment	Regenerating head	8hpa	dmso treatment	SRP654941	3.84
SRR36435313	Regenerating head · dmso treatment	Regenerating head	0hpa	dmso treatment	SRP654941	2.96
SRR36435280	Regenerating head · dmso treatment	Regenerating head	8hpa	dmso treatment	SRP654941	1.72
SRR36435271	Regenerating head · dmso treatment	Regenerating head	12hpa	dmso treatment	SRP654941	1.67
SRR36435312	Regenerating head · dmso treatment	Regenerating head	0hpa	dmso treatment	SRP654941	1.00
SRR36435296	Regenerating head · 25uM U0126 treatment	Regenerating head	1.5hpa	25uM U0126 treatment	SRP654941	13.99
SRR36435303	Regenerating head · 25uM U0126 treatment	Regenerating head	0hpa	25uM U0126 treatment	SRP654941	13.87
SRR36435281	Regenerating head · 25uM U0126 treatment	Regenerating head	0hpa	25uM U0126 treatment	SRP654941	13.63
SRR36435299	Regenerating head · 25uM U0126 treatment	Regenerating head	3hpa	25uM U0126 treatment	SRP654941	12.81
SRR36435294	Regenerating head · 25uM U0126 treatment	Regenerating head	1.5hpa	25uM U0126 treatment	SRP654941	11.26
SRR36435275	Regenerating head · 25uM U0126 treatment	Regenerating head	8hpa	25uM U0126 treatment	SRP654941	9.77
SRR36435295	Regenerating head · 25uM U0126 treatment	Regenerating head	1.5hpa	25uM U0126 treatment	SRP654941	9.46
SRR36435302	Regenerating head · 25uM U0126 treatment	Regenerating head	0hpa	25uM U0126 treatment	SRP654941	6.99
SRR36435301	Regenerating head · 25uM U0126 treatment	Regenerating head	0hpa	25uM U0126 treatment	SRP654941	6.29
SRR36435282	Regenerating head · 25uM U0126 treatment	Regenerating head	0hpa	25uM U0126 treatment	SRP654941	5.96
SRR36435298	Regenerating head · 25uM U0126 treatment	Regenerating head	3hpa	25uM U0126 treatment	SRP654941	5.94
SRR36435283	Regenerating head · 25uM U0126 treatment	Regenerating head	0hpa	25uM U0126 treatment	SRP654941	5.44
SRR36435276	Regenerating head · 25uM U0126 treatment	Regenerating head	8hpa	25uM U0126 treatment	SRP654941	4.35
SRR36435297	Regenerating head · 25uM U0126 treatment	Regenerating head	3hpa	25uM U0126 treatment	SRP654941	4.23
SRR36435274	Regenerating head · 25uM U0126 treatment	Regenerating head	8hpa	25uM U0126 treatment	SRP654941	3.42
SRR36435265	Regenerating foot · dmso treatment	Regenerating foot	1.5hpa	dmso treatment	SRP654941	14.03
SRR36435322	Regenerating foot · dmso treatment	Regenerating foot	0hpa	dmso treatment	SRP654941	12.93
SRR36435300	Regenerating foot · dmso treatment	Regenerating foot	3hpa	dmso treatment	SRP654941	12.75
SRR36435266	Regenerating foot · dmso treatment	Regenerating foot	1.5hpa	dmso treatment	SRP654941	12.07
SRR36435278	Regenerating foot · dmso treatment	Regenerating foot	3hpa	dmso treatment	SRP654941	12.01
SRR36435289	Regenerating foot · dmso treatment	Regenerating foot	3hpa	dmso treatment	SRP654941	11.30
SRR36435267	Regenerating foot · dmso treatment	Regenerating foot	1.5hpa	dmso treatment	SRP654941	8.53
SRR36435311	Regenerating foot · dmso treatment	Regenerating foot	0hpa	dmso treatment	SRP654941	7.46
SRR36435323	Regenerating foot · dmso treatment	Regenerating foot	0hpa	dmso treatment	SRP654941	6.35
SRR36435321	Regenerating foot · 25uM U0126 treatment	Regenerating foot	0hpa	25uM U0126 treatment	SRP654941	13.65
SRR36435315	Regenerating foot · 25uM U0126 treatment	Regenerating foot	1.5hpa	25uM U0126 treatment	SRP654941	12.46
SRR36435314	Regenerating foot · 25uM U0126 treatment	Regenerating foot	1.5hpa	25uM U0126 treatment	SRP654941	11.12
SRR36435317	Regenerating foot · 25uM U0126 treatment	Regenerating foot	3hpa	25uM U0126 treatment	SRP654941	10.99
SRR36435320	Regenerating foot · 25uM U0126 treatment	Regenerating foot	0hpa	25uM U0126 treatment	SRP654941	10.97
SRR36435316	Regenerating foot · 25uM U0126 treatment	Regenerating foot	1.5hpa	25uM U0126 treatment	SRP654941	10.09
SRR36435318	Regenerating foot · 25uM U0126 treatment	Regenerating foot	3hpa	25uM U0126 treatment	SRP654941	9.76
SRR36435319	Regenerating foot · 25uM U0126 treatment	Regenerating foot	3hpa	25uM U0126 treatment	SRP654941	9.41
SRR36435269	Regenerating head · u0126 treatment	Regenerating head	12hpa	u0126 treatment	SRP654941	9.53
SRR36435270	Regenerating head · u0126 treatment	Regenerating head	12hpa	u0126 treatment	SRP654941	2.93
SRR36435268	Regenerating head · u0126 treatment	Regenerating head	12hpa	u0126 treatment	SRP654941	1.57
SRR36435288	Whole animal · 25uM U0126 treatment	Whole animal	12h	25uM U0126 treatment	SRP654941	18.20
SRR36435287	Whole animal · 25uM U0126 treatment	Whole animal	12h	25uM U0126 treatment	SRP654941	17.19
SRR36435290	Whole animal · 25uM U0126 treatment	Whole animal	12h	25uM U0126 treatment	SRP654941	16.96
SRR36435291	Whole animal · dmso treatment	Whole animal	12h	dmso treatment	SRP654941	19.47
SRR36435292	Whole animal · dmso treatment	Whole animal	12h	dmso treatment	SRP654941	17.66
SRR36435293	Whole animal · dmso treatment	Whole animal	12h	dmso treatment	SRP654941	15.82
SRR36435264	Regenerating foot · u0126 treatment	Regenerating foot	0hpa	u0126 treatment	SRP654941	10.93

Source: CnidoSite RNA-seq expression matrices (HVULG_TPM, StringTie quantification over 60 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Hydra vulgaris tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	49	XP_065672791.1	0.977270746982279
Negatively correlated	11	NP_001274728.1	-0.829386700918902

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Hydra vulgaris, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

Dataset	Tissue / stage	Cells	Cell types	This gene	Marker of
HVULG_siebert_atlas	Whole animals · Adult (whole animal)	25,438	42	not in this dataset	–

A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

Peak calls overlapping this gene

Assay	Sample	Peaks	Region
ChIP-seq	H3K27ac_regenerating_head_0hr	2	Promoter (2-3kb) 1 · Promoter (<=1kb) 1
	H3K27ac_regenerating_head_4hr	2	Promoter (<=1kb) 1 · Intron 1
	H3K27ac_regenerating_head_6hr	2	Intron 2
	H3K27ac_whole_polyp_24hr_DMSO_control	1	Promoter (<=1kb) 1
	H3K27ac_wholeAnimal	1	Promoter (2-3kb) 1
	H3K4me2_regenerating_head_0hr	1	Intron 1
	H3K4me2_regenerating_head_4hr	1	Intron 1
	H3K4me2_regenerating_head_6hr	1	Intron 1
	H3K4me2_wholeAnimal	6	Intron 3 · Promoter (<=1kb) 2 · Promoter (1-2kb) 1
	H3K4me3_regenerating_head_0hr	1	Promoter (<=1kb) 1
	H3K4me3_regenerating_head_4hr	1	Intron 1
	H3K4me3_regenerating_head_6hr	1	Promoter (<=1kb) 1
	H3K4me3_wholeAnimal	1	Intron 1
	H4K20me1_regenerating_tips_8hrs	1	Intron 1
	H4K20me1_whole_polyp_ALP_treated	7	Intron 5 · Promoter (<=1kb) 1 · Exon 1

Browse the full epigenomic landscape of this species: ChIP-seq.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →