Genomic Location: sc0000016_pilon:2651813...2668174
NR annotation: XP_029204415.1, egl nine homolog 1-like isoform X4 [Acropora millepora]
Species Acropora hyacinthus · all data for this species · gene families
| CDS |
| ahya_s0016.g187.t2 |
| Transcript |
| ahya_s0016.g187.t2 |
| Protein |
| ahya_s0016.g187.t2 |
| UniProt accession | Description |
|---|---|
| P59722 | Egl nine homolog 1 (Fragment) OS=Rattus norvegicus OX=10116 GN=Egln1 PE=2 SV=2 |
| Q9GZT9 | Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1 |
| Q91YE3 | Egl nine homolog 1 OS=Mus musculus OX=10090 GN=Egln1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001346 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13640 all species → | 2OG-FeII_Oxy_3 | 2OG-Fe(II) oxygenase superfamily | Domain | Interproscan |
| PF01753 all species → | zf-MYND | MYND finger | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002893 all species → | Domain | Zinc finger, MYND-type | Interproscan |
| IPR044862 all species → | Domain | Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain | Interproscan |
| IPR005123 all species → | Domain | Oxoglutarate/iron-dependent dioxygenase | Interproscan |
| IPR006620 all species → | Domain | Prolyl 4-hydroxylase, alpha subunit | Interproscan |
| IPR051559 all species → | Family | Hypoxia-inducible factor prolyl hydroxylases | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12907 all species → | EGL NINE HOMOLOG-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005506 all species → | Molecular Function | iron ion binding | Interproscan |
| GO:0016705 all species → | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Interproscan |
| GO:0031418 all species → | Molecular Function | L-ascorbic acid binding | Interproscan |
| GO:0008198 all species → | Molecular Function | ferrous iron binding | Interproscan |
| GO:0031543 all species → | Molecular Function | peptidyl-proline dioxygenase activity | Interproscan |
| GO:0071456 all species → | Biological Process | cellular response to hypoxia | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K09592 | EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase | EC:1.14.11.29 | Renal cell carcinoma | ko05211 | deepkoala |
Transcript abundance of ahya_s0016.g187.t2 across 51 RNA-seq samples of Acropora hyacinthus. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| animal tissue · AH06 community | 17 | 0 | 0.00 | 0.00 | |
| animal tissue · AH75 community | 17 | 0 | 0.00 | 0.00 | |
| animal tissue · AH88 community | 17 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR4029951 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029952 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029953 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029954 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029955 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029956 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029957 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029958 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029959 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029963 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029974 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029985 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029996 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029998 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029999 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4030000 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4030001 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029960 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029961 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029962 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029964 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029965 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029966 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029967 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029968 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029969 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029970 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029971 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029972 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029973 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029975 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029976 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029977 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029978 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029979 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029980 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029981 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029982 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029983 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029984 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029986 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029987 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029988 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029989 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029990 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029991 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029992 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029993 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029994 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029995 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029997 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (AHYAC_TPM,
StringTie quantification over 51 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora hyacinthus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Acropora hyacinthus network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora hyacinthus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |