Genomic Location: sc0000056_pilon:239256...276450
NR annotation: UBR69922.1, NF-kB [Acropora cervicornis]
Species Acropora hyacinthus · all data for this species · gene families
| CDS |
| ahya_s0056.g8.t2 |
| Transcript |
| ahya_s0056.g8.t2 |
| Protein |
| ahya_s0056.g8.t2 |
| UniProt accession | Description |
|---|---|
| Q04861 | Nuclear factor NF-kappa-B p105 subunit OS=Gallus gallus OX=9031 GN=NFKB1 PE=2 SV=2 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit OS=Homo sapiens OX=9606 GN=NFKB1 PE=1 SV=2 |
| Q6F3J0 | Nuclear factor NF-kappa-B p105 subunit OS=Canis lupus familiaris OX=9615 GN=NFKB1 PE=2 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000719 (this species only) · gene tree & orthology |
| Transcription factor family | RHD · all TF in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00531 all species → | Death | Death domain | Domain | Interproscan |
| PF00023 all species → | Ank | Ankyrin repeat | Repeat | Interproscan |
| PF12796 all species → | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| PF00554 all species → | RHD_DNA_bind | Rel homology DNA-binding domain | Domain | Interproscan |
| PF16179 all species → | RHD_dimer | Rel homology dimerisation domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036770 all species → | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR000488 all species → | Domain | Death domain | Interproscan |
| IPR011029 all species → | Homologous_superfamily | Death-like domain superfamily | Interproscan |
| IPR011539 all species → | Domain | Rel homology domain, DNA-binding domain | Interproscan |
| IPR002110 all species → | Repeat | Ankyrin repeat | Interproscan |
| IPR000451 all species → | Family | NF-kappa-B/Dorsal | Interproscan |
| IPR008967 all species → | Homologous_superfamily | p53-like transcription factor, DNA-binding domain superfamily | Interproscan |
| IPR033926 all species → | Domain | NFkappaB IPT domain | Interproscan |
| IPR013783 all species → | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR002909 all species → | Domain | IPT domain | Interproscan |
| IPR014756 all species → | Homologous_superfamily | Immunoglobulin E-set | Interproscan |
| IPR032397 all species → | Domain | Rel homology dimerisation domain | Interproscan |
| IPR037059 all species → | Homologous_superfamily | Rel homology domain (RHD), DNA-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24169 all species → | NUCLEAR FACTOR NF-KAPPA-B PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0007165 all species → | Biological Process | signal transduction | Interproscan |
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0003700 all species → | Molecular Function | DNA-binding transcription factor activity | Interproscan |
| GO:0006355 all species → | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0000978 all species → | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Interproscan |
| GO:0000981 all species → | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K02580 | NFKB1; nuclear factor NF-kappa-B p105 subunit | - | Transcription factors | ko03000 | deepkoala |
Transcript abundance of ahya_s0056.g8.t2 across 51 RNA-seq samples of Acropora hyacinthus. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| animal tissue · AH06 community | 17 | 0 | 0.00 | 0.00 | |
| animal tissue · AH75 community | 17 | 0 | 0.00 | 0.00 | |
| animal tissue · AH88 community | 17 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR4029951 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029952 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029953 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029954 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029955 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029956 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029957 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029958 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029959 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029963 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029974 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029985 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029996 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029998 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029999 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4030000 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4030001 | animal tissue · AH06 community | animal tissue | not recorded | AH06 community | SRP082036 | 0.00 |
| SRR4029960 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029961 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029962 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029964 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029965 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029966 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029967 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029968 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029969 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029970 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029971 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029972 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029973 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029975 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029976 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029977 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029978 | animal tissue · AH75 community | animal tissue | not recorded | AH75 community | SRP082036 | 0.00 |
| SRR4029979 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029980 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029981 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029982 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029983 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029984 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029986 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029987 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029988 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029989 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029990 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029991 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029992 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029993 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029994 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029995 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
| SRR4029997 | animal tissue · AH88 community | animal tissue | not recorded | AH88 community | SRP082036 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (AHYAC_TPM,
StringTie quantification over 51 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora hyacinthus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Acropora hyacinthus network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora hyacinthus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |