Genomic Location: Ap1:27102829...27134318
NR annotation: XP_020626873.1, ER degradation-enhancing alpha-mannosidase-like protein 3 [Orbicella faveolata]
Species Astrangia poculata · all data for this species · gene families
| CDS |
| evm.model.Ap1.2652 |
| Transcript |
| evm.model.Ap1.2652 |
| Protein |
| evm.model.Ap1.2652 |
| UniProt accession | Description |
|---|---|
| Q6GQB9 | ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Xenopus laevis OX=8355 GN=edem3 PE=2 SV=2 |
| Q9BZQ6 | ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Homo sapiens OX=9606 GN=EDEM3 PE=1 SV=2 |
| Q2HXL6 | ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Mus musculus OX=10090 GN=Edem3 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005235 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01532 all species → | Glyco_hydro_47 | Glycosyl hydrolase family 47 | Repeat | Interproscan |
| PF02225 all species → | PA | PA domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036026 all species → | Homologous_superfamily | Seven-hairpin glycosidases | Interproscan |
| IPR012341 all species → | Homologous_superfamily | Six-hairpin glycosidase-like superfamily | Interproscan |
| IPR046450 all species → | Homologous_superfamily | PA domain superfamily | Interproscan |
| IPR044674 all species → | Family | ER degradation-enhancing alpha-mannosidase-like protein 1/2/3 | Interproscan |
| IPR001382 all species → | Family | Glycoside hydrolase family 47 | Interproscan |
| IPR003137 all species → | Domain | PA domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45679 all species → | ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004571 all species → | Molecular Function | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | Interproscan |
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0005975 all species → | Biological Process | carbohydrate metabolic process | Interproscan |
| GO:0004559 all species → | Molecular Function | alpha-mannosidase activity | Interproscan |
| GO:0005783 all species → | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:1904380 all species → | Biological Process | endoplasmic reticulum mannose trimming | Interproscan |
| GO:1904382 all species → | Biological Process | mannose trimming involved in glycoprotein ERAD pathway | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10086 | EDEM3; ER degradation enhancer, mannosidase alpha-like 3 | - | Lectins | ko04091 | deepkoala |
Transcript abundance of evm.model.Ap1.2652 across 49 RNA-seq samples of Astrangia poculata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organism · cold control | 14 | 0 | 0.00 | 0.00 | |
| whole organism · heat control | 12 | 0 | 0.00 | 0.00 | |
| whole organism · cold challenge | 12 | 0 | 0.00 | 0.00 | |
| whole organism · heat challenge | 11 | 0 | 0.00 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (APOCU_TPM,
StringTie quantification over 49 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
