Gene detail

Detailed information of evm.model.Ap10.643 in Astrangia poculata

Genomic Location: Ap10:6756008...6765148
NR annotation: XP_020616828.1, DNA-(apurinic or apyrimidinic site) lyase 2-like [Orbicella faveolata]
Species Astrangia poculata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6DDT4	DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Xenopus laevis OX=8355 GN=apex2.L PE=1 SV=1
Q68G58	DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Mus musculus OX=10090 GN=Apex2 PE=1 SV=1
Q5E9N9	DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Bos taurus OX=9913 GN=APEX2 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006719 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF06839 all species →	zf-GRF	GRF zinc finger	Domain	Interproscan
PF03372 all species →	Exo_endo_phos	Endonuclease/Exonuclease/phosphatase family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR010666 all species →	Domain	Zinc finger, GRF-type	Interproscan
IPR004808 all species →	Family	AP endonuclease 1	Interproscan
IPR036691 all species →	Homologous_superfamily	Endonuclease/exonuclease/phosphatase superfamily	Interproscan
IPR020847 all species →	Binding_site	AP endonuclease 1, binding site	Interproscan
IPR005135 all species →	Domain	Endonuclease/exonuclease/phosphatase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22748 all species →	AP ENDONUCLEASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0004518 all species →	Molecular Function	nuclease activity	Interproscan
GO:0006281 all species →	Biological Process	DNA repair	Interproscan
GO:0003906 all species →	Molecular Function	DNA-(apurinic or apyrimidinic site) endonuclease activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006284 all species →	Biological Process	base-excision repair	Interproscan
GO:0008081 all species →	Molecular Function	phosphoric diester hydrolase activity	Interproscan
GO:0008311 all species →	Molecular Function	double-stranded DNA 3'-5' DNA exonuclease activity	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0004519 all species →	Molecular Function	endonuclease activity	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10772	APEX2; AP endonuclease 2	EC:3.1.11.2	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.