Gene detail

Detailed information of evm.model.Ap11.1023 in Astrangia poculata

Genomic Location: Ap11:11287101...11314569
NR annotation: XP_020614938.1, DNA topoisomerase 2-alpha-like [Orbicella faveolata]
Species abbreviation APOCU · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

evm.model.Ap11.1023

atggcggccgaaacaagtgctttgaaggagataatgaataatgaccataactctaccaacaaagatgcattggctgccaagaagaagaaacgaatgtcagtggagagaatctaccaaaagaagacacaacttgagcacattttgcttcgtccagatacttacattggatctgttgagccgatcaaacagaatatgtgggtctatgatgcagacatgggagctattgtcagtaaagagataacatttgtgcctggtctgtacaagatctttgatgaaatattagtcaatgccgctgataacaagcaaagagatccttccatgggctgtgttaaaatcactattgatgcggaaaacaactccatcagtgtatggaatgatggacgtggcatccctgtcgaaatgcacaaggaacaaaaggtgtttgtgccgacattgatttttggtcaccttctgacatccagtaactacaatgacgcagaaaagaaagtcacaggaggacgtaatggttatggtgcaaaactgtgcaacatttttagcacaaagtttgtcgtggagacttgttcgtctgaatcaggaaaaaagtttaaacagacctggtcaaataacatgggaaaagctgcagaaccaattataaaagatttcagtggaaaggattacacttgtattacattcaaacctgacttggcaaagtttaagatggagactcttgacagtgacacggttgcattgttgaccaggagggcgtacgatgtggctggctccaccagagggattggagtatatctgaatggaaagaaaatacctattaagtcattcaaagactatgttggactttatctgaaaggcagagatgacgaagaggaattagcactggactcagagaataaaaagcctactaattctgttgtccatgaagtagtgaataaccgctgggaagtttgtgtcacaactagcatgaagggcttccagcaagcaagctttgtcaacggcatagctacaacaaaggggggaacacatgtcaattatgtaacagaccaaatcgcagaaaaactcatggctgcggtaaagaagaagaacaagggaggtgtagaagtcaagccttttcagatcaagaaccacttgtggatctttgtcaactgtctgatagaaaacccaagctttgactcacaaacaaaggaaaatatgaccctgagagctaaagcatttggatcgaagtgtgaatttagtgacaagtttattaaacaggttactcagtgtggtgttgtggaacacatcatgaattgggtgaaatttaaagcacagactcaactcaacaagaaatgtcagaagggcaaacacagtaaaatccgcggcattcctaaacttgatgatgctaatgatgcaggtggtagaaactctcagcagtgcacattgattctgactgagggagactcggccaagacgctggctgtgagtggtttgagtgttgttggcagggaccagtttggtgtgtttccactgcgtggcaagctgttgaatgtcagggacgcatcgcacaagcagattcttgaaaatgcagaaatcaacaatctaatcaagattgttgggctgcaatacaacaagaagtattcaacagaagacgaccttaaaagtttgaggtatggccacattatgatcatgacagatcaggatcaagatggctcgcacataaaggggctcctgattaacttcatacacagtaactggccaaacctgacacgcttgccgtttttggaggagtttatcactcctattgttaaggtcagcaagggtaaagaggagaaatccttctatagcattccagaatatgaggaatggaaaaacagcacagacaatgccaaatcctggaaagtaaagtactataaggggttgggcacgagcactcctaaggaggcaaaagaatactttgctgacatgcgacgtcatcagattcagttccaccatgaaggcgctgcatgtgatgaagccatactcatggccttcagtaaaaagaaagttaatgacagaaaagactggcttaaccatgcaatggaagatcgcaagtggagaaaacaacaagggctgtcagaggtgtatttgtatgagaaagacacaaagtctgtttcatactctgactttgtcaacaaagaattagttttgttctcaaatgcagacaatgaacgatcaatcccatgtctagtagatggtttcaaaccaggacaaaggaaagttctctttacgtgtcttaaaaggaacgacaaaagagaagtcaaagttgctcagcttgcaggttcagttgcagaattgtcagcataccaccacggcgagcaaagtctcatgggcacaataatcaacttagcccaaaattttgtaggtagcaataatgttaatctactgcagccagttggccagtttggcacacgtatccatggcggcaaggatgctgccagtccccgttacatcttcaccatgcttagtcctttagcgaagcttctatttcctgcccatgacatgccaagcctgacatacttgtttgatgacaaccagcctgttgaaccagaatggtactgccctattcttcccacagttatggttaacggcgctgaggggattggtactggttatagtaccaaggtgccaaattttgatgtgcggcaagtcgtcagcaatctgaagaagatgatcaatggagaggaacctgaagagatgattccttcatacaaggacttcacaggcaccatttctcaaattgatacccacaaattccttgtgcaaggtaatgtggacgtgattgacagcaaaactgtagaaatctcagaacttccagttggcacgtggacccaatcttacaaagagaatgtgctggagccaatgcttcatggtacagagaaagtgcctccaatccttactgattacaaggaataccacacagatgtcaccgtgaagtttgtgctaagtatgacagaggacaagctggccgaggctgagcagtcaggactgcataagaaatttaaacttgaaagcacaatctccactagtaacatggttctgtttgatgctttgggttgtctgcgcaagtatgagtcaccaaaagacatacttaaagagttttttgagcttcgtttagaaaggtatgccatccgcaaagcatggctggaagggatgctgactgcagaatcatccaagctgagcagtcaagcccgctttatcttggaaaagattgacggacaaattattcttgaaaacagatccaagcgtgacattatcacatccctcgtacagcatggattcccatctgatccagtaaaagcttggaaagatctgcaaaaatcaaatgcacccgaagaagacgtggacgatgcctccagtgtggcgagctctgcctcaagtgctggtggcccggacttcaactatttattatctatgtcaatgctttctctctctagagagaaaaaggaagaactgctcaaggaacgagataataagatggaggagcttgagacattacgtggcaaatccccgcaggacctctggttagaggatcttgaactcttcctggaagagttggagaatgttgagcaacaggagagggaagatcaagaaatgtgtcttaaacctaaaggaggccgttcacagcagcagaaaaagaaaccctcaaagcaagctgcaaagaaacctgacaacaaacccaaggctcaggaaaagaagcctgctgttaatgctgaagaaaagcagaagaagaaagcagaaggccagggcaaagccacagcagctagcaagaaagcagagaagagcaacgactcatgggagtttgacgagggagataccgctcctcctgtgaagtcactggcagacagactggcgcagcggcaaaaactgcccagttcatcatcgtcttcagccggtagtggcactgagtcagtaggcagcagtgcctcaaggtccaagaagcagaccacgcttgagatgttcggtacaaagaagaaagcagccaagaaggctgctgcggaaagtgatgatgattttattatgcagtttagtgatgaagaggatgctgcgccgccacctgcgaagaggactgctagatcagctgctcctaaggccttttcaattagttctgatgatgatgatgatgatttaatggttacatcagcgaaaagccagaagaagtctaataatgcaagccttgacagtgatgcggagtcagataagagtgatgtacaggctacacgagctctcatacagaagctctctcctgctaaaccagcaaacactcttcagtcaaaagcaaaagagacttcagaagacagtgtagcgagcaagactacaaagaaacaaccttccaaagccaagcaaacagcaggggcagcaaagaagcccgccgcaaaaaaggcacaggcttcttctaaaggatctactggagatgagagtgctgatgctgacttgcaaaagaaacagacagctaagaaaggcaagggacgaaaaataatttcatcagcctttgatagcagtgaagactctgatgcagaaattgcttcctcaaagaaacctgcagctgctaaaggaaaggccataaagcctaaaaagtcacccccgaagaagtcaaaaccaacagcagaaagctccagcgacgatgaaccactggaaaaggctgtccagagccgatctcagcgcgctggcagagctaaagctactgtgaagtatttcgaggatgagagtgatagtgatgataaggagaatgataacacatggttagggtctgacagtgactttgatactgagtag

Transcript

evm.model.Ap11.1023

ATGGCGGCCGAAACAAGTGCTTTGAAGGAGATAATGAATAATGACCATAACTCTACCAACAAAGATGCATTGGCTGCCAAGAAGAAGAAACGAATGTCAGTGGAGAGAATCTACCAAAAGAAGACACAACTTGAGCACATTTTGCTTCGTCCAGATACTTACATTGGATCTGTTGAGCCGATCAAACAGAATATGTGGGTCTATGATGCAGACATGGGAGCTATTGTCAGTAAAGAGATAACATTTGTGCCTGGTCTGTACAAGATCTTTGATGAAATATTAGTCAATGCCGCTGATAACAAGCAAAGAGATCCTTCCATGGGCTGTGTTAAAATCACTATTGATGCGGAAAACAACTCCATCAGTGTATGGAATGATGGACGTGGCATCCCTGTCGAAATGCACAAGGAACAAAAGGTGTTTGTGCCGACATTGATTTTTGGTCACCTTCTGACATCCAGTAACTACAATGACGCAGAAAAGAAAGTCACAGGAGGACGTAATGGTTATGGTGCAAAACTGTGCAACATTTTTAGCACAAAGTTTGTCGTGGAGACTTGTTCGTCTGAATCAGGAAAAAAGTTTAAACAGACCTGGTCAAATAACATGGGAAAAGCTGCAGAACCAATTATAAAAGATTTCAGTGGAAAGGATTACACTTGTATTACATTCAAACCTGACTTGGCAAAGTTTAAGATGGAGACTCTTGACAGTGACACGGTTGCATTGTTGACCAGGAGGGCGTACGATGTGGCTGGCTCCACCAGAGGGATTGGAGTATATCTGAATGGAAAGAAAATACCTATTAAGTCATTCAAAGACTATGTTGGACTTTATCTGAAAGGCAGAGATGACGAAGAGGAATTAGCACTGGACTCAGAGAATAAAAAGCCTACTAATTCTGTTGTCCATGAAGTAGTGAATAACCGCTGGGAAGTTTGTGTCACAACTAGCATGAAGGGCTTCCAGCAAGCAAGCTTTGTCAACGGCATAGCTACAACAAAGGGGGGAACACATGTCAATTATGTAACAGACCAAATCGCAGAAAAACTCATGGCTGCGGTAAAGAAGAAGAACAAGGGAGGTGTAGAAGTCAAGCCTTTTCAGATCAAGAACCACTTGTGGATCTTTGTCAACTGTCTGATAGAAAACCCAAGCTTTGACTCACAAACAAAGGAAAATATGACCCTGAGAGCTAAAGCATTTGGATCGAAGTGTGAATTTAGTGACAAGTTTATTAAACAGGTTACTCAGTGTGGTGTTGTGGAACACATCATGAATTGGGTGAAATTTAAAGCACAGACTCAACTCAACAAGAAATGTCAGAAGGGCAAACACAGTAAAATCCGCGGCATTCCTAAACTTGATGATGCTAATGATGCAGGTGGTAGAAACTCTCAGCAGTGCACATTGATTCTGACTGAGGGAGACTCGGCCAAGACGCTGGCTGTGAGTGGTTTGAGTGTTGTTGGCAGGGACCAGTTTGGTGTGTTTCCACTGCGTGGCAAGCTGTTGAATGTCAGGGACGCATCGCACAAGCAGATTCTTGAAAATGCAGAAATCAACAATCTAATCAAGATTGTTGGGCTGCAATACAACAAGAAGTATTCAACAGAAGACGACCTTAAAAGTTTGAGGTATGGCCACATTATGATCATGACAGATCAGGATCAAGATGGCTCGCACATAAAGGGGCTCCTGATTAACTTCATACACAGTAACTGGCCAAACCTGACACGCTTGCCGTTTTTGGAGGAGTTTATCACTCCTATTGTTAAGGTCAGCAAGGGTAAAGAGGAGAAATCCTTCTATAGCATTCCAGAATATGAGGAATGGAAAAACAGCACAGACAATGCCAAATCCTGGAAAGTAAAGTACTATAAGGGGTTGGGCACGAGCACTCCTAAGGAGGCAAAAGAATACTTTGCTGACATGCGACGTCATCAGATTCAGTTCCACCATGAAGGCGCTGCATGTGATGAAGCCATACTCATGGCCTTCAGTAAAAAGAAAGTTAATGACAGAAAAGACTGGCTTAACCATGCAATGGAAGATCGCAAGTGGAGAAAACAACAAGGGCTGTCAGAGGTGTATTTGTATGAGAAAGACACAAAGTCTGTTTCATACTCTGACTTTGTCAACAAAGAATTAGTTTTGTTCTCAAATGCAGACAATGAACGATCAATCCCATGTCTAGTAGATGGTTTCAAACCAGGACAAAGGAAAGTTCTCTTTACGTGTCTTAAAAGGAACGACAAAAGAGAAGTCAAAGTTGCTCAGCTTGCAGGTTCAGTTGCAGAATTGTCAGCATACCACCACGGCGAGCAAAGTCTCATGGGCACAATAATCAACTTAGCCCAAAATTTTGTAGGTAGCAATAATGTTAATCTACTGCAGCCAGTTGGCCAGTTTGGCACACGTATCCATGGCGGCAAGGATGCTGCCAGTCCCCGTTACATCTTCACCATGCTTAGTCCTTTAGCGAAGCTTCTATTTCCTGCCCATGACATGCCAAGCCTGACATACTTGTTTGATGACAACCAGCCTGTTGAACCAGAATGGTACTGCCCTATTCTTCCCACAGTTATGGTTAACGGCGCTGAGGGGATTGGTACTGGTTATAGTACCAAGGTGCCAAATTTTGATGTGCGGCAAGTCGTCAGCAATCTGAAGAAGATGATCAATGGAGAGGAACCTGAAGAGATGATTCCTTCATACAAGGACTTCACAGGCACCATTTCTCAAATTGATACCCACAAATTCCTTGTGCAAGGTAATGTGGACGTGATTGACAGCAAAACTGTAGAAATCTCAGAACTTCCAGTTGGCACGTGGACCCAATCTTACAAAGAGAATGTGCTGGAGCCAATGCTTCATGGTACAGAGAAAGTGCCTCCAATCCTTACTGATTACAAGGAATACCACACAGATGTCACCGTGAAGTTTGTGCTAAGTATGACAGAGGACAAGCTGGCCGAGGCTGAGCAGTCAGGACTGCATAAGAAATTTAAACTTGAAAGCACAATCTCCACTAGTAACATGGTTCTGTTTGATGCTTTGGGTTGTCTGCGCAAGTATGAGTCACCAAAAGACATACTTAAAGAGTTTTTTGAGCTTCGTTTAGAAAGGTATGCCATCCGCAAAGCATGGCTGGAAGGGATGCTGACTGCAGAATCATCCAAGCTGAGCAGTCAAGCCCGCTTTATCTTGGAAAAGATTGACGGACAAATTATTCTTGAAAACAGATCCAAGCGTGACATTATCACATCCCTCGTACAGCATGGATTCCCATCTGATCCAGTAAAAGCTTGGAAAGATCTGCAAAAATCAAATGCACCCGAAGAAGACGTGGACGATGCCTCCAGTGTGGCGAGCTCTGCCTCAAGTGCTGGTGGCCCGGACTTCAACTATTTATTATCTATGTCAATGCTTTCTCTCTCTAGAGAGAAAAAGGAAGAACTGCTCAAGGAACGAGATAATAAGATGGAGGAGCTTGAGACATTACGTGGCAAATCCCCGCAGGACCTCTGGTTAGAGGATCTTGAACTCTTCCTGGAAGAGTTGGAGAATGTTGAGCAACAGGAGAGGGAAGATCAAGAAATGTGTCTTAAACCTAAAGGAGGCCGTTCACAGCAGCAGAAAAAGAAACCCTCAAAGCAAGCTGCAAAGAAACCTGACAACAAACCCAAGGCTCAGGAAAAGAAGCCTGCTGTTAATGCTGAAGAAAAGCAGAAGAAGAAAGCAGAAGGCCAGGGCAAAGCCACAGCAGCTAGCAAGAAAGCAGAGAAGAGCAACGACTCATGGGAGTTTGACGAGGGAGATACCGCTCCTCCTGTGAAGTCACTGGCAGACAGACTGGCGCAGCGGCAAAAACTGCCCAGTTCATCATCGTCTTCAGCCGGTAGTGGCACTGAGTCAGTAGGCAGCAGTGCCTCAAGGTCCAAGAAGCAGACCACGCTTGAGATGTTCGGTACAAAGAAGAAAGCAGCCAAGAAGGCTGCTGCGGAAAGTGATGATGATTTTATTATGCAGTTTAGTGATGAAGAGGATGCTGCGCCGCCACCTGCGAAGAGGACTGCTAGATCAGCTGCTCCTAAGGCCTTTTCAATTAGTTCTGATGATGATGATGATGATTTAATGGTTACATCAGCGAAAAGCCAGAAGAAGTCTAATAATGCAAGCCTTGACAGTGATGCGGAGTCAGATAAGAGTGATGTACAGGCTACACGAGCTCTCATACAGAAGCTCTCTCCTGCTAAACCAGCAAACACTCTTCAGTCAAAAGCAAAAGAGACTTCAGAAGACAGTGTAGCGAGCAAGACTACAAAGAAACAACCTTCCAAAGCCAAGCAAACAGCAGGGGCAGCAAAGAAGCCCGCCGCAAAAAAGGCACAGGCTTCTTCTAAAGGATCTACTGGAGATGAGAGTGCTGATGCTGACTTGCAAAAGAAACAGACAGCTAAGAAAGGCAAGGGACGAAAAATAATTTCATCAGCCTTTGATAGCAGTGAAGACTCTGATGCAGAAATTGCTTCCTCAAAGAAACCTGCAGCTGCTAAAGGAAAGGCCATAAAGCCTAAAAAGTCACCCCCGAAGAAGTCAAAACCAACAGCAGAAAGCTCCAGCGACGATGAACCACTGGAAAAGGCTGTCCAGAGCCGATCTCAGCGCGCTGGCAGAGCTAAAGCTACTGTGAAGTATTTCGAGGATGAGAGTGATAGTGATGATAAGGAGAATGATAACACATGGTTAGGGTCTGACAGTGACTTTGATACTGAGTAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P41515	DNA topoisomerase 2-alpha OS=Cricetulus griseus OX=10029 GN=TOP2A PE=2 SV=1
O42131	DNA topoisomerase 2-beta OS=Gallus gallus OX=9031 GN=TOP2B PE=2 SV=1
O46374	DNA topoisomerase 2-alpha OS=Sus scrofa OX=9823 GN=TOP2A PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002437 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00521 all species →	DNA_topoisoIV	DNA gyrase/topoisomerase IV, subunit A	Family	Interproscan
PF00204 all species →	DNA_gyraseB	DNA gyrase B	Domain	Interproscan
PF01751 all species →	Toprim	Toprim domain	Family	Interproscan
PF02518 all species →	HATPase_c	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	Domain	Interproscan
PF16898 all species →	TOPRIM_C	C-terminal associated domain of TOPRIM	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR050634 all species →	Family	DNA Topoisomerase II Enzyme	Interproscan
IPR013759 all species →	Homologous_superfamily	DNA topoisomerase, type IIA, subunit B, C-terminal	Interproscan
IPR002205 all species →	Domain	DNA topoisomerase, type IIA, domain A	Interproscan
IPR020568 all species →	Homologous_superfamily	Ribosomal protein uS5 domain 2-type superfamily	Interproscan
IPR001154 all species →	Family	DNA topoisomerase II, eukaryotic-type	Interproscan
IPR001241 all species →	Family	DNA topoisomerase, type IIA	Interproscan
IPR003594 all species →	Domain	Histidine kinase/HSP90-like ATPase	Interproscan
IPR013758 all species →	Homologous_superfamily	DNA topoisomerase, type IIA, domain A, alpha-beta	Interproscan
IPR014721 all species →	Homologous_superfamily	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	Interproscan
IPR018522 all species →	Conserved_site	DNA topoisomerase, type IIA, conserved site	Interproscan
IPR006171 all species →	Domain	TOPRIM domain	Interproscan
IPR013506 all species →	Domain	DNA topoisomerase, type IIA, subunit B, domain 2	Interproscan
IPR036890 all species →	Homologous_superfamily	Histidine kinase/HSP90-like ATPase superfamily	Interproscan
IPR013757 all species →	Homologous_superfamily	DNA topoisomerase, type IIA, alpha-helical domain superfamily	Interproscan
IPR034157 all species →	Domain	DNA topoisomerase 2, TOPRIM domain	Interproscan
IPR013760 all species →	Homologous_superfamily	DNA topoisomerase, type IIA-like domain superfamily	Interproscan
IPR031660 all species →	Domain	C-terminal associated domain of TOPRIM	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10169 all species →	DNA TOPOISOMERASE/GYRASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000712 all species →	Biological Process	resolution of meiotic recombination intermediates	Interproscan
GO:0000819 all species →	Biological Process	sister chromatid segregation	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0003918 all species →	Molecular Function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006265 all species →	Biological Process	DNA topological change	Interproscan
GO:0006259 all species →	Biological Process	DNA metabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K03164	TOP2; DNA topoisomerase II	EC:5.6.2.2	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.