Gene detail

Detailed information of evm.model.Ap11.210 in Astrangia poculata

Genomic Location: Ap11:2624627...2647883
NR annotation: XP_020600691.1, histone-lysine N-methyltransferase EZH2-like [Orbicella faveolata]
Species Astrangia poculata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

evm.model.Ap11.210

atggaaagtgatttaaaacgacttgctcggctagaatatctcaaacttcggcaatccaagcaaacggagaaagttgaagctgtaaagaattgttttacagaaaaccaacaagccataaaagagttgctatggaaacggaaacagatacaaggaagcgacaagcagcaagttgtgccgtttatttctccagctgagcagctcccttccacaagaaaatgctctgcctatagtgggtttggacatggtactcaacacactgttttaaggactctgtatgctgttcagccgctgccgcagttcttcacctggtctcctctacagcaaaactacatggttgaagatgagacagtcttgcataatattccgtacatgggagaggaggttttagaccaggatgggtcattcattgaagaacttattaaaaactacgaaggacgagtacacaacaccccagagcatgtgtttgatgaagcagcccttacagatgatctgcttgttcagctggttgaagccttgaagaaacacaagcagtctgccaagaataacacagaaactgaggcagcaaaggaaaaggagaaagaaaaaagtgaagattccaacatagttgctgaaaattccccaaaagatgaagagaaacctgcagaatcagcggagaaacatgatgaactgtttgacgccattgcatctctttttcctgataagggcttaatgggagctgaggtttatcgaaggtacaagaatgtgctggatcgtaaaaatggtgaactgccacctgaatgtacaccaaatattgacagtcccaaggcacaatctgtttcaagagaacaaagcttgcactcatttcatatgctgttctgtagaagatgttacaagtatgactgcttcatgcatggttggcgaacacttcccacgcagataaaacgaaagagtcctgttgacctacaagaaacaagtccttgtggagctgactgctatatgcatgtgaagaacttacatgaggaagagagcagtggtaagtcatctgaggcagtcagcaccagacgaaggagtcgagccagcagcaaggataataaaggagggaaaggaaactctaaaggatcaggatttcccagcccagacagtgcagcgactggtgacaacagtccagaacattctttggtgaccagtgaatggacaggagctgaggcgtcgttgttccgtgttcttaaaccaatctattgtaataactactgcagtattgcaaacttgattcactccaagacttgtaaggaggtgtacctgagggcattacaagagtcacacgagccattaccaacagctgatgatcaagacacaccaccaaggaaaaagaaaagaaagcacaggatgtggtctctacactgcagaaagattcaactgaaaaaagacagcacctctacgcatgtgtacaactacattccatgtgaccatcctggacagccttgtgatcaatcatgcatctgtgtagctacacaaaacttctgtgagaagttctgtcagtgcagcactgactgtcaaaatcgcttccctggctgccgctgtaaagcacagtgcaacaccaaacagtgcccatgcttcctagcggtcagagaatgtgacccagacctctgccaaacatgtggagctgattcatttgatggaacaactaacatttgctgtaggaatgtcggccttcaacgcggtcaaagaaagcatcttttactcgcgccttctgacgtggctggctggggaatttacatcaaggaatcttgtaaaaagaatgaattcattggcgaatactgcggagagatcatctctcaagacgaagcggaccgcagaggaaaggtttacgacaagtacatgtgcagcttcttgtttaatctaaacaatgacttcgttgtggacgctactcgtaaagggaacaaaatcaggttcgcaaaccattccatcagtccaaattgttacgccaaagtaatgatggtaaacggagatcacaggattggaatttttgccaaacgtgacattgaagatggagaggaactgttctttgattataggtacagtgccacggatgctctcaagtttgttggaatcgaacgagatgtagacttcgccttaagatga

Transcript

evm.model.Ap11.210

GTTCATAACACAGAAAATTTTGCGAGCGAGAGCAGTATGGAAAGTGATTTAAAACGACTTGCTCGGCTAGAATATCTCAAACTTCGGCAATCCAAGCAAACGGAGAAAGTTGAAGCTGTAAAGAATTGTTTTACAGAAAACCAACAAGCCATAAAAGAGTTGCTATGGAAACGGAAACAGATACAAGGAAGCGACAAGCAGCAAGTTGTGCCGTTTATTTCTCCAGCTGAGCAGCTCCCTTCCACAAGAAAATGCTCTGCCTATAGTGGGTTTGGACATGGTACTCAACACACTGTTTTAAGGACTCTGTATGCTGTTCAGCCGCTGCCGCAGTTCTTCACCTGGTCTCCTCTACAGCAAAACTACATGGTTGAAGATGAGACAGTCTTGCATAATATTCCGTACATGGGAGAGGAGGTTTTAGACCAGGATGGGTCATTCATTGAAGAACTTATTAAAAACTACGAAGGACGAGTACACAACACCCCAGAGCATGTGTTTGATGAAGCAGCCCTTACAGATGATCTGCTTGTTCAGCTGGTTGAAGCCTTGAAGAAACACAAGCAGTCTGCCAAGAATAACACAGAAACTGAGGCAGCAAAGGAAAAGGAGAAAGAAAAAAGTGAAGATTCCAACATAGTTGCTGAAAATTCCCCAAAAGATGAAGAGAAACCTGCAGAATCAGCGGAGAAACATGATGAACTGTTTGACGCCATTGCATCTCTTTTTCCTGATAAGGGCTTAATGGGAGCTGAGGTTTATCGAAGGTACAAGAATGTGCTGGATCGTAAAAATGGTGAACTGCCACCTGAATGTACACCAAATATTGACAGTCCCAAGGCACAATCTGTTTCAAGAGAACAAAGCTTGCACTCATTTCATATGCTGTTCTGTAGAAGATGTTACAAGTATGACTGCTTCATGCATGGTTGGCGAACACTTCCCACGCAGATAAAACGAAAGAGTCCTGTTGACCTACAAGAAACAAGTCCTTGTGGAGCTGACTGCTATATGCATGTGAAGAACTTACATGAGGAAGAGAGCAGTGGTAAGTCATCTGAGGCAGTCAGCACCAGACGAAGGAGTCGAGCCAGCAGCAAGGATAATAAAGGAGGGAAAGGAAACTCTAAAGGATCAGGATTTCCCAGCCCAGACAGTGCAGCGACTGGTGACAACAGTCCAGAACATTCTTTGGTGACCAGTGAATGGACAGGAGCTGAGGCGTCGTTGTTCCGTGTTCTTAAACCAATCTATTGTAATAACTACTGCAGTATTGCAAACTTGATTCACTCCAAGACTTGTAAGGAGGTGTACCTGAGGGCATTACAAGAGTCACACGAGCCATTACCAACAGCTGATGATCAAGACACACCACCAAGGAAAAAGAAAAGAAAGCACAGGATGTGGTCTCTACACTGCAGAAAGATTCAACTGAAAAAAGACAGCACCTCTACGCATGTGTACAACTACATTCCATGTGACCATCCTGGACAGCCTTGTGATCAATCATGCATCTGTGTAGCTACACAAAACTTCTGTGAGAAGTTCTGTCAGTGCAGCACTGACTGTCAAAATCGCTTCCCTGGCTGCCGCTGTAAAGCACAGTGCAACACCAAACAGTGCCCATGCTTCCTAGCGGTCAGAGAATGTGACCCAGACCTCTGCCAAACATGTGGAGCTGATTCATTTGATGGAACAACTAACATTTGCTGTAGGAATGTCGGCCTTCAACGCGGTCAAAGAAAGCATCTTTTACTCGCGCCTTCTGACGTGGCTGGCTGGGGAATTTACATCAAGGAATCTTGTAAAAAGAATGAATTCATTGGCGAATACTGCGGAGAGATCATCTCTCAAGACGAAGCGGACCGCAGAGGAAAGGTTTACGACAAGTACATGTGCAGCTTCTTGTTTAATCTAAACAATGACTTCGTTGTGGACGCTACTCGTAAAGGGAACAAAATCAGGTTCGCAAACCATTCCATCAGTCCAAATTGTTACGCCAAAGTAATGATGGTAAACGGAGATCACAGGATTGGAATTTTTGCCAAACGTGACATTGAAGATGGAGAGGAACTGTTCTTTGATTATAGGTACAGTGCCACGGATGCTCTCAAGTTTGTTGGAATCGAACGAGATGTAGACTTCGCCTTAAGATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q4V863	Histone-lysine N-methyltransferase EZH2 OS=Xenopus laevis OX=8355 GN=ezh2-b PE=2 SV=1
Q28D84	Histone-lysine N-methyltransferase EZH2 OS=Xenopus tropicalis OX=8364 GN=ezh2 PE=2 SV=1
Q15910	Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004328 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF21358 all species →	Ezh2_MCSS	Ezh2, MCSS domain	Domain	Interproscan
PF00856 all species →	SET	SET domain	Family	Interproscan
PF18264 all species →	preSET_CXC	CXC domain	Domain	Interproscan
PF18118 all species →	PRC2_HTH_1	Polycomb repressive complex 2 tri-helical domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR048358 all species →	Domain	EZH1/2, MCSS domain	Interproscan
IPR044439 all species →	Domain	EZH2, SET domain	Interproscan
IPR046341 all species →	Homologous_superfamily	SET domain superfamily	Interproscan
IPR001214 all species →	Domain	SET domain	Interproscan
IPR026489 all species →	Domain	CXC domain	Interproscan
IPR045318 all species →	Family	Histone-lysine N-methyltransferase EZH1/2-like	Interproscan
IPR033467 all species →	Domain	Tesmin/TSO1-like CXC domain	Interproscan
IPR041355 all species →	Domain	Pre-SET CXC domain	Interproscan
IPR041343 all species →	Domain	Polycomb repressive complex 2 subunit EZH1/EZH2, tri-helical domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45747 all species →	HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0046976 all species →	Molecular Function	histone H3K27 methyltransferase activity	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0003682 all species →	Molecular Function	chromatin binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006338 all species →	Biological Process	chromatin remodeling	Interproscan
GO:0031507 all species →	Biological Process	heterochromatin formation	Interproscan
GO:0035098 all species →	Cellular Component	ESC/E(Z) complex	Interproscan
GO:0042054 all species →	Molecular Function	histone methyltransferase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11430	EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2	EC:2.1.1.356	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.